Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Hynek Strnad"'
Autor:
Imtissal Krayem, Yahya Sohrabi, Helena Havelková, Elena S. Gusareva, Hynek Strnad, Marie Čepičková, Valeryia Volkova, Iryna Kurey, Jarmila Vojtíšková, Milena Svobodová, Peter Demant, Marie Lipoldová
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Leishmaniasis, a disease caused by parasites of Leishmania spp., endangers more than 1 billion people living in endemic countries and has three clinical forms: cutaneous, mucocutaneous, and visceral. Understanding of individual differences in suscept
Externí odkaz:
https://doaj.org/article/3e718d78d1e24996b2ce7247054e2c1b
Autor:
Václav Šmíd, Karel Dvořák, Kamila Stehnová, Hynek Strnad, Josep Rubert, Jan Stříteský, Barbora Staňková, Milena Stránská, Jana Hajšlová, Radan Brůha, Libor Vítek
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17226 (2023)
The pathogenesis of non-alcoholic fatty liver disease (NAFLD) is associated with abnormalities of liver lipid metabolism. On the contrary, a diet enriched with n-3 polyunsaturated fatty acids (n-3-PUFAs) has been reported to ameliorate the progressio
Externí odkaz:
https://doaj.org/article/8dc7c626a1274dd2ac170c0229c75454
Autor:
Petr Soukal, Štěpánka Hrdá, Anna Karnkowska, Rafał Milanowski, Jana Szabová, Miluše Hradilová, Hynek Strnad, Čestmír Vlček, Ivan Čepička, Vladimír Hampl
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Euglenids represent a group of protists with diverse modes of feeding. To date, only a partial genomic sequence of Euglena gracilis and transcriptomes of several phototrophic and secondarily osmotrophic species are available, while primarily
Externí odkaz:
https://doaj.org/article/9485f77f444f443da288a4ac83180e3a
Autor:
Imtissal Krayem, Yahya Sohrabi, Eliška Javorková, Valeriya Volkova, Hynek Strnad, Helena Havelková, Jarmila Vojtíšková, Aigerim Aidarova, Vladimír Holáň, Peter Demant, Marie Lipoldová
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Differences in frequencies of blood cell subpopulations were reported to influence the course of infections, atopic and autoimmune diseases, and cancer. We have discovered a unique mouse strain B10.O20 containing extremely high frequency of myeloid-d
Externí odkaz:
https://doaj.org/article/8e0953753a104350a2d56780f5471812
Autor:
Sona Hubackova, Miroslav Pribyl, Lenka Kyjacova, Alena Moudra, Rastislav Dzijak, Barbora Salovska, Hynek Strnad, Vojtech Tambor, Terezie Imrichova, Jiri Svec, Pavel Vodicka, Radka Vaclavikova, Lukas Rob, Jiri Bartek, Zdenek Hodny
Publikováno v:
Molecular Oncology, Vol 13, Iss 7, Pp 1467-1489 (2019)
Radiation and chemotherapy represent standard‐of‐care cancer treatments. However, most patients eventually experience tumour recurrence, treatment failure and metastatic dissemination with fatal consequences. To elucidate the molecular mechanisms
Externí odkaz:
https://doaj.org/article/245b820657594210941ebc8f6ccbec17
Autor:
Martin Palus, Yahya Sohrabi, Karl W. Broman, Hynek Strnad, Matyáš Šíma, Daniel Růžek, Valeriya Volkova, Martina Slapničková, Jarmila Vojtíšková, Lucie Mrázková, Jiří Salát, Marie Lipoldová
Publikováno v:
BMC Neuroscience, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Tick-borne encephalitis (TBE) is the main tick-borne viral infection in Eurasia. Its manifestations range from inapparent infections and fevers with complete recovery to debilitating or fatal encephalitis. The basis of this hetero
Externí odkaz:
https://doaj.org/article/633680645c54450f98e56610ebc84b4e
Autor:
Jakub Ridl, Jachym Suman, Serena Fraraccio, Miluse Hradilova, Michal Strejcek, Tomas Cajthaml, Andrea Zubrova, Tomas Macek, Hynek Strnad, Ondrej Uhlik
Publikováno v:
Standards in Genomic Sciences, Vol 13, Iss 1, Pp 1-10 (2018)
Abstract In this study, following its isolation from contaminated soil, the genomic sequence of Pseudomonas alcaliphila strain JAB1 (=DSM 26533), a biphenyl-degrading bacterium, is reported and analyzed in relation to its extensive degradative capabi
Externí odkaz:
https://doaj.org/article/4fe52b643de348c9b8f28c08e12b0668
Autor:
Helena Gbelcová, Silvie Rimpelová, Zdeněk Knejzlík, Jana Šáchová, Michal Kolář, Hynek Strnad, Vanda Repiská, Walter Cosimo D’Acunto, Tomáš Ruml, Libor Vítek
Publikováno v:
Lipids in Health and Disease, Vol 16, Iss 1, Pp 1-10 (2017)
Abstract Background Statin treatment of hypercholesterolemia is accompanied also with depletion of the mevalonate intermediates, including farnesyl pyrophosphate (FPP) and geranylgeranyl pyrophosphate (GGPP) necessary for proper function of small GTP
Externí odkaz:
https://doaj.org/article/1564237be422436784cf65eb07216dd9
Publikováno v:
Molecules, Vol 26, Iss 12, p 3528 (2021)
Statins have been widely used for the treatment of hypercholesterolemia due to their ability to inhibit HMG-CoA reductase, the rate-limiting enzyme of de novo cholesterol synthesis, via the so-called mevalonate pathway. However, their inhibitory acti
Externí odkaz:
https://doaj.org/article/c244182daf034fcaba7cfcb59a3d4577
Autor:
Shohag Bhargava, Brian Cox, Christiana Polydorou, Veronika Gresakova, Vladimir Korinek, Hynek Strnad, Radislav Sedlacek, Trevor Allan Epp, Kallayanee Chawengsaksophak
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Gastrulation initiates with the formation of the primitive streak, during which, cells of the epiblast delaminate to form the mesoderm and definitive endoderm. At this stage, the pluripotent cell population of the epiblast undergoes very rap
Externí odkaz:
https://doaj.org/article/a75928153f674212b2fdce97ae6ec453