Zobrazeno 1 - 10
of 356
pro vyhledávání: '"Hynda K. Kleinman"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
It has been accepted for many years that tumor cells spread via the circulation to distant sites. The latency period between treatment and tumor recurrence has been attributed to dormant cells in distant organs that emerge and grow as metastatic tumo
Externí odkaz:
https://doaj.org/article/43bfd2dafb1c451db817eceedb822fe9
Autor:
Chae Eun Kim, Hynda K. Kleinman, Gabriel Sosne, George W Ousler, Kyeongsoon Kim, Sinwook Kang, Jaewook Yang
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract This study evaluated the clinical activity of RGN-259 (thymosin β4) in comparison with cyclosporine A (CsA), diquafosol (DQS), and lifitegrast (LFA) in a murine model of dry eye. The model was NOD.B10-H2 b mice in a 30–40% humidified envi
Externí odkaz:
https://doaj.org/article/209b22d9f1ca4439aacdcb974310bacf
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-9 (2017)
Abstract Neuronal Ceroid Lipofuscinosis (NCL), also known as Batten disease, is a group of genetically distinct lysosomal disorders that mainly affect the central nervous system, resulting in progressive motor and cognitive decline primarily in child
Externí odkaz:
https://doaj.org/article/e67ddb93f0df4fe1a7008a5e8aa42403
Autor:
Hynda K. Kleinman
Publikováno v:
Career Options in the Pharmaceutical and Biomedical Industry ISBN: 9783031149108
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1bfbcdbbf04c74fbdf2676e86ee1cf7
https://doi.org/10.1007/978-3-031-14911-5_18
https://doi.org/10.1007/978-3-031-14911-5_18
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627020
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9619d7b2d6e4d1239d5f1a9c0a2206d3
https://doi.org/10.1007/978-1-0716-2703-7_7
https://doi.org/10.1007/978-1-0716-2703-7_7
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2572
The mechanism of cancer cell migration from the primary tumor toward secondary sites is not fully understood. In addition to intravascular cellular migration, angiotropic extravascular migratory metastasis (EVMM) has been recognized as a metastatic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5faed15ea35e85fbcfa561ba5ebe1bd
https://pubmed.ncbi.nlm.nih.gov/36161410
https://pubmed.ncbi.nlm.nih.gov/36161410
Publikováno v:
J Cell Commun Signal
Basement membranes are thin sheets of extracellular matrix with many diverse roles in the body. Those in normal tissue are also highly insoluble and resist attempts to extract and characterize their components. A mouse tumor, the EHS tumor, has provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b21f5d5f80286c2f0e62235c817d14
https://doi.org/10.1007/s12079-021-00643-1
https://doi.org/10.1007/s12079-021-00643-1
Autor:
Gabriel Sosne, Hynda K. Kleinman, Clark Springs, Robert Hollis Gross, Jihye Sung, Shinwook Kang
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 554
We determined the efficacy and safety of 0.1% RGN-259 ophthalmic solution (containing the regenerative protein thymosin ß4) in promoting the healing of persistent epithelial defects in patients with Stages 2 and 3 neurotrophic keratopathy. Complete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec6c99de81d05e43cf2f8fe102e9a5d
https://doi.org/10.3390/ijms24010554
https://doi.org/10.3390/ijms24010554
Publikováno v:
European Journal of Dermatology. 29:459-467
Thymosin β4 is a naturally-occurring regenerative protein present in almost all cells and body fluids, including wound fluid. In multiple preclinical injury models, it promotes dermal repair and tissue regeneration. Thymosin β4 acts by increasing k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6edebb3e0a1bf41ed561908f9dc65c
https://doi.org/10.1684/ejd.2019.3642
https://doi.org/10.1684/ejd.2019.3642
Publikováno v:
Current eye research. 45(11)
Purpose: This study aimed to determine the effect of thymosin beta 4 (Tβ4) on human corneal epithelial cell migration and the downstream signaling pathways. Tβ4 has a role in tissue development, ce...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262586f7cbfd4d5a4d8bde266bbf8be1
https://pubmed.ncbi.nlm.nih.gov/32223337
https://pubmed.ncbi.nlm.nih.gov/32223337