Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hymavathi Reddy Vari"'
Autor:
Carol Dangelmaier, Hymavathi Reddy Vari, Dhruv N Vajipayajula, Manal Elzoheiry, Monica Wright, Ashvin Iyer, Alexander Y Tsygankov, Satya P Kunapuli
Publikováno v:
Platelets, Vol 35, Iss 1 (2024)
Receptor-induced tyrosine phosphorylation of spleen tyrosine kinase (Syk) has been studied extensively in hematopoietic cells. Metabolic mapping and high-resolution mass spectrometry, however, indicate that one of the most frequently detected phospho
Externí odkaz:
https://doaj.org/article/0bbd4456bd874d078cc934ff7055b695
Autor:
Pankaj Kumar Singh, Carol A. Dangelmaier, Hymavathi Reddy Vari, Alexander Y. Tsygankov, Satya P. Kunapuli
Publikováno v:
Platelets, Vol 34, Iss 1 (2023)
Alternate splicing is among the regulatory mechanisms imparting functional diversity in proteins. Studying protein isoforms generated through alternative splicing is therefore critical for understanding protein functions in many biological systems. S
Externí odkaz:
https://doaj.org/article/59a190ce04fa438db5cc20248019132a
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 3, Pp n/a-n/a (2022)
Abstract Background C‐type lectin receptor family members play a role in many cells including platelets, where they are crucial in the separation of lymphatic and blood vessels during development. The C‐type lectin‐like receptor 2 (CLEC‐2) re
Externí odkaz:
https://doaj.org/article/72d0ccdac96641efbe161bda7ed217b2
Publikováno v:
ERJ Open Research. 9:00694-2022
BackgroundAirway epithelial cells from patients with COPD show suboptimal innate immune responses to nontypeableHaemophilus influenzae(NTHi) and Toll-like receptor (TLR)2 ligands despite expressing TLR2 similar to normal airway epithelial cells, but
Toll-like receptors (TLR) play a pivotal role in stimulating innate immune responses of airway epithelial cells to bacterial and viral infections. Airway epithelial cells from patients with chronic obstructive pulmonary disease (COPD) show suboptimal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ae5df15f82db5039cd4c03c285f21c4
https://doi.org/10.21203/rs.3.rs-1734139/v1
https://doi.org/10.21203/rs.3.rs-1734139/v1
Autor:
Uma S. Sajjan, Sudhir Kotnala, Joao Gimenes-Junior, Wuyan Li, Nathaniel Xander, Hymavathi Reddy Vari, Nicole Owuar
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Forkhead transcription factor class O (FOXO)3a, which plays a critical role in a wide variety of cellular processes, was also found to regulate cell-type-specific antiviral responses. Airway epithelial cells express FOXO3a and play an important role
Autor:
Nathaniel Xander, Wuyan Li, Hymavathi Reddy Vari, Nathaniel Marchetti, Rewees Eskandar, Sudhir Bolla, Umadevi S. Sajjan
Publikováno v:
J Immunol
IFN responses to viral infection are necessary to establish intrinsic antiviral state, but if unchecked can lead to heightened inflammation. Recently, we showed that TLR2 activation contributes to limitation of rhinovirus (RV)–induced IFN response
Autor:
John C, Kostyak, Benjamin, Mauri, Carol, Dangelmaier, Hymavathi Reddy, Vari, Akruti, Patel, Monica, Wright, Haritha, Reddy, Alexander Y, Tsygankov, Satya P, Kunapuli
Publikováno v:
Journal of Biological Chemistry. 298:102189
Immune cells express receptors bearing an immune tyrosine activation motif (ITAM) containing two YXXL motifs or hemITAMs containing only one YXXL motif. Phosphorylation of the ITAM/hemITAM is mediated by Src family kinases allowing for the binding an