Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Hyman M. Schipper"'
Autor:
Marisa Cressatti, Hyman M. Schipper
Publikováno v:
NeuroSci, Vol 3, Iss 2, Pp 284-299 (2022)
α-Synuclein is a key driver of the pathogenesis of Parkinson disease (PD). Heme oxygenase-1 (HO-1), a stress protein that catalyzes the conversion of heme to biliverdin, carbon monoxide and free ferrous iron, is elevated in PD-affected neural tissue
Externí odkaz:
https://doaj.org/article/9a0ade33d33340b7aff6c9b643907b20
Autor:
Heather Pekeles, Hamid Y. Qureshi, Hemant K. Paudel, Hyman M. Schipper, Mervyn Gornistky, Howard Chertkow
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 10, Iss 1, Pp 53-60 (2018)
Abstract Introduction Total tau (t‐tau) and phosphorylated tau (p‐tau) are abnormally elevated in the brain and cerebrospinal fluid of individuals with Alzheimer's disease (AD). Tau is also present in the salivary gland tissue and saliva, and sal
Externí odkaz:
https://doaj.org/article/315ed81fcb7f4bd2a9c7cf5d0e4525c8
Autor:
Jing Chen-Roetling, Pramod Kamalapathy, Yang Cao, Wei Song, Hyman M. Schipper, Raymond F. Regan
Publikováno v:
Neurobiology of Disease, Vol 102, Iss , Pp 140-146 (2017)
Pharmacotherapies that increase CNS expression of heme oxygenase-1 (HO-1) and other antioxidant proteins have improved outcome in experimental models of spontaneous intracerebral hemorrhage (ICH). In order to more specifically investigate the relatio
Externí odkaz:
https://doaj.org/article/47792c23248747779c35dc979a72f341
Autor:
Hyman M. Schipper, Wei Song
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 3, Pp 5400-5419 (2015)
Heme oxygenase-1 (HO-1) is a 32 kDa protein which catalyzes the breakdown of heme to free iron, carbon monoxide and biliverdin. The Hmox1 promoter contains numerous consensus sequences that render the gene exquisitely sensitive to induction by divers
Externí odkaz:
https://doaj.org/article/54c1a2c3503741aab6f690d7aedf668f
Autor:
Olivier C. Maes, Steven Kravitz, Yogesh Mawal, Haixiang Su, Adrienne Liberman, Khalil Mehindate, Dan Berlin, Demetrios J. Sahlas, Howard M. Chertkow, Howard Bergman, Calvin Melmed, Hyman M. Schipper
Publikováno v:
Neurobiology of Disease, Vol 24, Iss 1, Pp 89-100 (2006)
Heme oxygenase-1 (HO-1) mRNA and protein levels are diminished in Alzheimer disease (AD) blood, cerebrospinal fluid (CSF) and choroid plexus. Herein, the presence of a heme oxygenase-1 suppressor (HOS) factor was ascertained by astroglial bioassay, b
Externí odkaz:
https://doaj.org/article/5d306103714642e195e2f1cd40755d9e
Autor:
Hyman M. Schipper
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2010 (2010)
Decreased 𝛽-amyloid1-42 and increased phospho-tau protein levels in the cerebrospinal fluid (CSF) are currently the most accurate chemical neurodiagnostics of sporadic Alzheimer disease (AD). A report (2007) of the Third Canadian Consensus Confere
Externí odkaz:
https://doaj.org/article/b99b49446667423889495a832558b3f2
Autor:
Hyman M. Schipper, Jinsong Jiao, Gheorghe Roman, Jason Z. Vlahakis, Guoan Liu, Bin Xu, Yingjie Xu, Wei Song, Jie Su, Walter A. Szarek, Ajay Gupta, Tarek A. Bismar, Moulay A. Alaoui-Jamali
Supplementary Figure 1 from A Novel Experimental Heme Oxygenase-1–Targeted Therapy for Hormone-Refractory Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b51fa2689f9f3c8c227c89a8d074805
https://doi.org/10.1158/0008-5472.22381164.v1
https://doi.org/10.1158/0008-5472.22381164.v1
Autor:
Hyman M. Schipper, Jinsong Jiao, Gheorghe Roman, Jason Z. Vlahakis, Guoan Liu, Bin Xu, Yingjie Xu, Wei Song, Jie Su, Walter A. Szarek, Ajay Gupta, Tarek A. Bismar, Moulay A. Alaoui-Jamali
Supplementary Figure 4 from A Novel Experimental Heme Oxygenase-1–Targeted Therapy for Hormone-Refractory Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61494a7562f2eea4958f4e37c26425c8
https://doi.org/10.1158/0008-5472.22381155
https://doi.org/10.1158/0008-5472.22381155
Autor:
Hyman M. Schipper, Jinsong Jiao, Gheorghe Roman, Jason Z. Vlahakis, Guoan Liu, Bin Xu, Yingjie Xu, Wei Song, Jie Su, Walter A. Szarek, Ajay Gupta, Tarek A. Bismar, Moulay A. Alaoui-Jamali
Supplementary Methods, Figure Legends 1-4 from A Novel Experimental Heme Oxygenase-1–Targeted Therapy for Hormone-Refractory Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d807dec060348a0f0ce07d32079a8f
https://doi.org/10.1158/0008-5472.22381152.v1
https://doi.org/10.1158/0008-5472.22381152.v1
Autor:
Hyman M. Schipper, Jinsong Jiao, Gheorghe Roman, Jason Z. Vlahakis, Guoan Liu, Bin Xu, Yingjie Xu, Wei Song, Jie Su, Walter A. Szarek, Ajay Gupta, Tarek A. Bismar, Moulay A. Alaoui-Jamali
Supplementary Figure 2 from A Novel Experimental Heme Oxygenase-1–Targeted Therapy for Hormone-Refractory Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc2ee4a833ab94afcbb485954fe4c92
https://doi.org/10.1158/0008-5472.22381161.v1
https://doi.org/10.1158/0008-5472.22381161.v1