Evaluating the efficacy of a priming dose of cyclophosphamide prior to pembrolizumab to treat metastatic triple negative breast cancer

Autor: Karen McKinnon, Kristen Cowens, Dante Bortone, Lisa Carey, Trevor Jolly, Hyman Muss, Katherine Reeder-Hayes, Rebecca Kaltman, Rachel Jankowitz, Vinay Gudena, Oludamilola Olajide, Charles Perou, Carey K Anders, Mark G Woodcock, Amanda E D Van Swearingen, Dominic T Moore, Maria J Sambade, Sonia Laurie, Alexander Robeson, Oleg Kolupaev, Luz A Cuaboy, Amy L Garrett, Benjamin C Calhoun, Alec D Wilkinson, E Claire Dees, Benjamin G Vincent, Jonathan S Serody

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)

Purpose Triple negative breast cancer (TNBC) is characterized by the presence of immune cells in the tumor microenvironment, however, the response to single-agent immune checkpoint inhibitor (ICI) therapy is modest. Preclinical models have demonstrat

Externí odkaz: https://doaj.org/article/4b4477f689454bc2b5fe6bd317c412e0

Performance of cellular senescence measure, p16, and DNA methylation clocks in a clinically relevant model of age acceleration

Autor: Mina S. Sedrak, Anne Knecht, Susan L. Strum, Canlan Sun, Yuan Chun Ding, Jingran Ji, Thomas A. White, Kirsten Nyrop, Nathan K. LeBrasseur, Susan L. Neuhausen, Natalia Mitin, Hyman Muss

Cellular senescence and DNA methylation are primary aging mechanisms emerging as a potential means of monitoring human aging and evaluating interventions thought to either accelerate or slow an individual’s aging trajectory. However, it is largely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e84c3135e09a828e2be0c9d8073d91c
https://doi.org/10.1101/2023.05.06.23289535

NCCN Virtual Patient Advocacy Summit: Cancer Across the Lifespan

Autor: Kara, Martin, Alyssa A, Schatz, Jan S, White, Hyman, Muss, Aarati, Didwania, Leigh, Gallo, Robert W, Carlson

Publikováno v: Journal of the National Comprehensive Cancer Network. 19:1395-1400

Patients with cancer have widely divergent experiences throughout their care from screening through survivorship. Differences in care delivery and outcomes may be due to varying patient preferences, patient needs according to stage of life, access to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34332815ff7855fdb7017ca96d21f28a
https://doi.org/10.6004/jnccn.2021.7087

Supporting Patients with Cancer after Dobbs v. Jackson Women's Health Organization

Autor: Andrew G Shuman, Matti S Aapro, Benjamin Anderson, Katherine Arbour, Pedro C Barata, Aditya Bardia, Eduardo Bruera, Bruce A Chabner, Herbert Chen, Edwin Choy, Pierfranco Conte, Giuseppe Curigliano, Don Dizon, Eileen O’Reilly, Antonio Tito Fojo, Hans Gelderblom, Timothy A Graubert, Jayne S Gurtler, Evan Hall, Fred R Hirsch, Ahmed Idbaih, David H Ilson, Michael Kelley, Carlo La Vecchia, Heinz Ludwig, Beverly Moy, Hyman Muss, Frans Opdam, Rebecca D Pentz, Marshall R Posner, Jeffrey S Ross, Adrian Sacher, Suresh Senan, Enrique Soto-Perez-de-Celis, Kenneth K Tanabe, Jan B Vermorken, Eric Wehrenberg-Klee, Susan E Bates

Publikováno v: The Oncologist. AlphaMed Press
The oncologist
Shuman, A G, Aapro, M S, Anderson, B, Arbour, K, Barata, P C, Bardia, A, Bruera, E, Chabner, B A, Chen, H, Choy, E, Conte, P, Curigliano, G, Dizon, D, O'Reilly, E, Tito Fojo, A, Gelderblom, H, Graubert, T A, Gurtler, J S, Hall, E, Hirsch, F R, Idbaih, A, Ilson, D H, Kelley, M, La Vecchia, C, Ludwig, H, Moy, B, Muss, H, Opdam, F, Pentz, R D, Posner, M R, Ross, J S, Sacher, A, Senan, S, Perez de Celis, E S, Tanabe, K K, Vermorken, J B, Wehrenberg-Klee, E & Bates, S E 2022, ' Supporting Patients with Cancer after Dobbs v. Jackson Women's Health Organization ', The Oncologist . https://doi.org/10.1093/oncolo/oyac165

In the context of cancer, whether or not to choose pregnancy termination represents a difficult and multifaceted decision. In this editorial, members of The Oncologist editorial team attempt to contextualize the potential implications of the recent S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ecc854d9ed429acd22943cfd187fb8
https://hdl.handle.net/1887/3563468

Treatment decision conversations, symptoms, and functional status in older adults with advanced cancer: An exploratory study utilizing mixed methods

Autor: Lorinda A, Coombs, Sarah, Neller, Christina, Wilson, Paul, Mihas, Daniel, Reuland, Hyman, Muss, Kathi, Mooney

Publikováno v: Journal of Geriatric Oncology. 14:101414

Adults 65 years of age or older with metastatic cancer face complicated treatment decisions. Few studies have explored the process with oncology clinicians during clinic encounters. Our exploratory study evaluated whether symptom burden or functional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ee5ba0c8192a2659bf22be010661b5
https://doi.org/10.1016/j.jgo.2022.12.002