Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Hylde, Zirpoli"'
Publikováno v:
Frontiers in Neurology, Vol 11 (2021)
Therapeutic hypothermia (HT) is a currently accepted treatment for neonatal asphyxia and is a promising strategy in adult stroke therapy. We previously reported that acute administration of docosahexaenoic acid (DHA) triglyceride emulsion (tri-DHA) p
Externí odkaz:
https://doaj.org/article/03664fea1d354677806e16f8d2ffc468
Autor:
Karen M. O'Shea, Radha Ananthakrishnan, Qing Li, Nosirudeen Quadri, Devi Thiagarajan, Gopalkrishna Sreejit, Lingjie Wang, Hylde Zirpoli, Juan Francisco Aranda, Arthur S. Alberts, Ann Marie Schmidt, Ravichandran Ramasamy
Publikováno v:
EBioMedicine, Vol 26, Iss C, Pp 165-174 (2017)
The biochemical, ionic, and signaling changes that occur within cardiomyocytes subjected to ischemia are exacerbated by reperfusion; however, the precise mechanisms mediating myocardial ischemia/reperfusion (I/R) injury have not been fully elucidated
Externí odkaz:
https://doaj.org/article/a4833b9b626f400b8610176c912adfc6
Autor:
Devi Thiagarajan, Nosirudeen Quadri, Shabnam Jawahar, Hylde Zirpoli, Carmen Hurtado del Pozo, Raquel López‐Díez, Syed Nurul Hasan, Gautham Yepuri, Paul F. Gugger, Brian S. Finlin, Philip A. Kern, Kenneth Gabbay, Ann Marie Schmidt, Ravichandran Ramasamy
Publikováno v:
Obesity. 30:1647-1658
Aldose reductase (AKR1B1 in humans; Akr1b3 in mice), a key enzyme of the polyol pathway, mediates lipid accumulation in the murine heart and liver. The study objective was to explore potential roles for AKR1B1/Akr1b3 in the pathogenesis of obesity an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::904d5d3d26df57e3d54d4f48cbddddd3
https://doi.org/10.1002/oby.23496
https://doi.org/10.1002/oby.23496
Autor:
Korapat Mayurasakorn, Zoya V Niatsetskaya, Sergey A Sosunov, Jill J Williams, Hylde Zirpoli, Iliyan Vlasakov, Richard J Deckelbaum, Vadim S Ten
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160870 (2016)
Treatment with triglyceride emulsions of docosahexaenoic acid (tri-DHA) protected neonatal mice against hypoxia-ischemia (HI) brain injury. The mechanism of this neuroprotection remains unclear. We hypothesized that administration of tri-DHA enriches
Externí odkaz:
https://doaj.org/article/25908a8bcdaf4ecc90ae9ce63fff873f
Autor:
Hylde Zirpoli, Denny Joseph Kollareth Manual, Sergey A Sosunov, Sundas Rashid, Jesse Ng, Nasi Huang, Jaroslav Lralovec, Korapat Mayurasakorn, James A Hamilton, Vadim S Ten, Richard J Deckelbaum
Publikováno v:
Stroke. 53
Introduction: Omega-3 (n-3) fatty acids (FAs), specifically docohexaenoic acid (DHA) and eicosapentaenoic acid (EPA), act as bioactive unsaturated lipids with pleiotropic effects, affording neuroprotection in ischemic brain injury. Hypothesis: We rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8feba75231e15b083d08e1007845e02d
https://doi.org/10.1161/str.53.suppl_1.tp250
https://doi.org/10.1161/str.53.suppl_1.tp250
Autor:
Rishi R, Agrawal, Delfina, Larrea, Yimeng, Xu, Lingyan, Shi, Hylde, Zirpoli, Leslie G, Cummins, Valentina, Emmanuele, Donghui, Song, Taekyung D, Yun, Frank P, Macaluso, Wei, Min, Steven G, Kernie, Richard J, Deckelbaum, Estela, Area-Gomez
Publikováno v:
Cellular and molecular neurobiology.
Traumatic brain injury (TBI) can lead to neurodegenerative diseases such as Alzheimer's disease (AD) through mechanisms that remain incompletely characterized. Similar to AD, TBI models present with cellular metabolic alterations and modulated cleava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4629d395a6236709d40a2447d21de976
https://pubmed.ncbi.nlm.nih.gov/36571634
https://pubmed.ncbi.nlm.nih.gov/36571634
Autor:
Hylde Zirpoli, Mariane Abdillahi, Nosirudeen Quadri, Radha Ananthakrishnan, Lingjie Wang, Rosa Rosario, Zhengbin Zhu, Richard J Deckelbaum, Ravichandran Ramasamy
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116274 (2015)
Dietary n-3 fatty acids (FAs) may reduce cardiovascular disease risk. We questioned whether acute administration of n-3 rich triglyceride (TG) emulsions could preserve cardiac function and decrease injury after ischemia/reperfusion (I/R) insult. We u
Externí odkaz:
https://doaj.org/article/8bfdb80efdbd4289a5d6456aec1c00d2
Autor:
Rishi R. Agrawal, Delfina Larrea, Yimeng Xu, Lingyan Shi, Hylde Zirpoli, Leslie G. Cummins, Valentina Emmanuele, Donghui Song, Taekyung D. Yun, Frank P. Macaluso, Wei Min, Steven G. Kernie, Richard J. Deckelbaum, Estela Area-Gomez
Publikováno v:
Cellular and molecular neurobiology, vol 43, iss 5
23 p.-5 fig.-3 tab.-1 graph. abst.
Traumatic brain injury (TBI) can lead to neurodegenerative diseases such as Alzheimer’s disease (AD) through mechanisms that remain incompletely characterized. Similar to AD, TBI models present with cellular
Traumatic brain injury (TBI) can lead to neurodegenerative diseases such as Alzheimer’s disease (AD) through mechanisms that remain incompletely characterized. Similar to AD, TBI models present with cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a876e62e597700eaec7f7abd0330a1fa
https://doi.org/10.1101/2020.11.13.381756
https://doi.org/10.1101/2020.11.13.381756
Autor:
Charles N. Serhan, Vadim S. Ten, Richard J. Deckelbaum, Zequn Liu, Charlotte C. Jouvene, Hylde Zirpoli, Rajasekhar Ramakrishnan, Denny Joseph Manual Kollareth
Publikováno v:
Prostaglandins Leukot Essent Fatty Acids
We recently reported that acute injection of docosahexaenoic acid (DHA) triglyceride emulsions (tri-DHA) conferred neuroprotection after hypoxic-ischemic (HI) injury in a neonatal mouse stroke model. We showed that exogenous DHA increased concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc27bb4f22e69808bd390b9cdfdbb1d
https://pubmed.ncbi.nlm.nih.gov/33038830
https://pubmed.ncbi.nlm.nih.gov/33038830
Cardiovascular diseases are a leading cause of death worldwide. Polyunsaturated fatty acids (PUFA), particularly n−3 PUFA, are widely regarded as cardioprotective. We review and compare evidence on the benefits, and in some cases adverse effects, o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e6606c32d419664cd0f76922886023f
https://doi.org/10.1016/b978-0-12-819404-1.00021-x
https://doi.org/10.1016/b978-0-12-819404-1.00021-x