Acute Exercise Improves Insulin Clearance and Increases the Expression of Insulin-Degrading Enzyme in the Liver and Skeletal Muscle of Swiss Mice.

Autor: Mirian A Kurauti, Ricardo Freitas-Dias, Sandra M Ferreira, Jean F Vettorazzi, Tarlliza R Nardelli, Hygor N Araujo, Gustavo J Santos, Everardo M Carneiro, Antonio C Boschero, Luiz F Rezende, José M Costa-Júnior

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0160239 (2016)

The effects of exercise on insulin clearance and IDE expression are not yet fully elucidated. Here, we have explored the effect of acute exercise on insulin clearance and IDE expression in lean mice. Male Swiss mice were subjected to a single bout of

Externí odkaz: https://doaj.org/article/6e483a6754274371a90ef65c60c84ecf

The MicroRNA miR-696 is regulated by SNARK and reduces mitochondrial activity in mouse skeletal muscle through Pgc1α inhibition

Autor: André L. Queiroz, Sarah J. Lessard, Amanda T. Ouchida, Hygor N. Araujo, Dawit A. Gonçalves, Dimitrius Santiago P. Simões Fróes Guimarães, Bruno G. Teodoro, Kawai So, Enilza M. Espreafico, Michael F. Hirshman, Luciane C. Alberici, Isis do Carmo Kettelhut, Laurie J. Goodyear, Leonardo R. Silveira

Publikováno v: Molecular Metabolism, Vol 51, Iss , Pp 101226- (2021)

Objective: MicroRNAs (miRNA) are known to regulate the expression of genes involved in several physiological processes including metabolism, mitochondrial biogenesis, proliferation, differentiation, and cell death. Methods: Using “in silico” anal

Externí odkaz: https://doaj.org/article/f16977abeca54a81845fd637f904eadd

Regulation of Lin28a-miRNA

Autor: Hygor N, Araujo, Tanes I, Lima, Dimitrius Santiago P S F, Guimarães, Andre G, Oliveira, Bianca C, Favero-Santos, Renato C S, Branco, Rafaela Mariano, da Silva Araújo, Alvaro F B, Dantas, Alex, Castro, Mara Patrícia T, Chacon-Mikahil, Elaine, Minatel, Murilo V, Geraldo, Everardo Magalhães, Carneiro, Alice C, Rodrigues, Vihang A, Narkar, Leonardo R, Silveira

Publikováno v: Am J Physiol Cell Physiol

Lin28a/miRNA let-7b-5p pathway has emerged as a key regulators of energy homeostasis in the skeletal muscle. However, the mechanism through which this pathway is regulated in the skeletal muscle has remained unclear. We have found that 8 wk of aerobi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::995d4f8045bc81785d64f342142d09e6
https://pubmed.ncbi.nlm.nih.gov/32697599

Offspring from trained male mice inherit improved muscle mitochondrial function through PPAR co-repressor modulation

Autor: Ricardo, Freitas-Dias, Tanes I, Lima, Jose Maria, Costa-Junior, Luciana M, Gonçalves, Hygor N, Araujo, Flavia M M, Paula, Gustavo J, Santos, Renato Chaves Souto, Branco, Kristy, Ou, Klaus H, Kaestner, Leonardo R, Silveira, Camila A M, Oliveira, Antonio C, Boschero, Claudio C, Zoppi, Everardo M, Carneiro

Publikováno v: Life Sciences. 291:120239

Aim Investigate whether inheritance of improved skeletal muscle mitochondrial function and its association with glycemic control are multigenerational benefits of exercise.Male Swiss mice were subjected to 8 weeks of endurance training and mated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff895796986437346103015e38483e43
https://doi.org/10.1016/j.lfs.2021.120239

The MicroRNA miR-696 is regulated by SNARK and reduces mitochondrial activity in mouse skeletal muscle through Pgc1α inhibition

Autor: Bruno G. Teodoro, Dawit A. P. Gonçalves, Kawai So, Sarah J. Lessard, Isis do Carmo Kettelhut, Enilza Maria Espreáfico, Leonardo R. Silveira, Laurie J. Goodyear, Luciane C. Alberici, Dimitrius Santiago P.S.F. Guimarães, André L. Queiroz, Hygor N. Araujo, Michael F. Hirshman, Amanda Tomie Ouchida

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Molecular Metabolism, Vol 51, Iss, Pp 101226-(2021)
Molecular Metabolism

Objective MicroRNAs (miRNA) are known to regulate the expression of genes involved in several physiological processes including metabolism, mitochondrial biogenesis, proliferation, differentiation, and cell death. Methods Using “in silico” analys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ac309ab2d58d1d494d13c13eb8600a
https://doi.org/10.1016/j.molmet.2021.101226