Výsledky vyhledávání - "Hygor N, Araujo"

Akademický článek

The MicroRNA miR-696 is regulated by SNARK and reduces mitochondrial activity in mouse skeletal muscle through Pgc1α inhibition

Autor: André L. Queiroz, Sarah J. Lessard, Amanda T. Ouchida, Hygor N. Araujo, Dawit A. Gonçalves, Dimitrius Santiago P. Simões Fróes Guimarães, Bruno G. Teodoro, Kawai So, Enilza M. Espreafico, Michael F. Hirshman, Luciane C. Alberici, Isis do Carmo Kettelhut, Laurie J. Goodyear, Leonardo R. Silveira

Publikováno v: Molecular Metabolism, Vol 51, Iss , Pp 101226- (2021)

Objective: MicroRNAs (miRNA) are known to regulate the expression of genes involved in several physiological processes including metabolism, mitochondrial biogenesis, proliferation, differentiation, and cell death. Methods: Using “in silico” anal

Externí odkaz: https://doaj.org/article/f16977abeca54a81845fd637f904eadd

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Phytomodulatory proteins isolated from Calotropis procera latex promote glycemic control by improving hepatic mitochondrial function in HepG2 cells

Autor: Hygor N. Araujo, Ariclécio Cunha de Oliveira, Regina de Jesus das Neves, Tanes I. Lima, Renata Prado Vasconcelos, Paula Alexandre de Freitas, Keciany Alves de Oliveira, Marina Gabrielle Guimarães de Almeida, André Gustavo de Oliveira, Márcio V. Ramos, Leonardo R. Silveira, Bianca Cristine Favero-Santos, Dimitrius Santiago P.S.F. Guimarães

Publikováno v: Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 29, Iss 9, Pp 1061-1069 (2021)

The medicinal uses of Calotropis procera are diverse, yet some of them are based on effects that still lack scientific support. Control of diabetes is one of them. Recently, latex proteins from C. procera latex (LP) have been shown to promote in vivo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589b5f0bac9dfc1fd17b68bf7d99c68a
http://europepmc.org/articles/PMC8463474

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Akademický článek

Acute Exercise Improves Insulin Clearance and Increases the Expression of Insulin-Degrading Enzyme in the Liver and Skeletal Muscle of Swiss Mice.

Autor: Mirian A Kurauti, Ricardo Freitas-Dias, Sandra M Ferreira, Jean F Vettorazzi, Tarlliza R Nardelli, Hygor N Araujo, Gustavo J Santos, Everardo M Carneiro, Antonio C Boschero, Luiz F Rezende, José M Costa-Júnior

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0160239 (2016)

The effects of exercise on insulin clearance and IDE expression are not yet fully elucidated. Here, we have explored the effect of acute exercise on insulin clearance and IDE expression in lean mice. Male Swiss mice were subjected to a single bout of

Externí odkaz: https://doaj.org/article/6e483a6754274371a90ef65c60c84ecf

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Regulation of Lin28a-miRNA

Autor: Hygor N, Araujo, Tanes I, Lima, Dimitrius Santiago P S F, Guimarães, Andre G, Oliveira, Bianca C, Favero-Santos, Renato C S, Branco, Rafaela Mariano, da Silva Araújo, Alvaro F B, Dantas, Alex, Castro, Mara Patrícia T, Chacon-Mikahil, Elaine, Minatel, Murilo V, Geraldo, Everardo Magalhães, Carneiro, Alice C, Rodrigues, Vihang A, Narkar, Leonardo R, Silveira

Publikováno v: Am J Physiol Cell Physiol

Lin28a/miRNA let-7b-5p pathway has emerged as a key regulators of energy homeostasis in the skeletal muscle. However, the mechanism through which this pathway is regulated in the skeletal muscle has remained unclear. We have found that 8 wk of aerobi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::995d4f8045bc81785d64f342142d09e6
https://pubmed.ncbi.nlm.nih.gov/32697599

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Regulation of Lin28a-miRNA let-7b-5p pathway in skeletal muscle cells by peroxisome proliferator-activated receptor delta

Autor: Dimitrius Santiago P.S.F. Guimarães, Leonardo R. Silveira, Hygor N. Araujo, Renato Chaves Souto Branco, Alex Castro, Tanes I. Lima, André Gustavo de Oliveira, Alice Cristina Rodrigues, Murilo Vieira Geraldo, R. Araújo, Mara Patrícia Traina Chacon-Mikahil, Alvaro F B Dantas, Bianca Cristine Favero-Santos, Vihang A. Narkar, Everardo M. Carneiro, Elaine Minatel

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c44802e74e8f03ee495809bc3b611cd

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Offspring from trained male mice inherit improved muscle mitochondrial function through PPAR co-repressor modulation

Autor: Ricardo, Freitas-Dias, Tanes I, Lima, Jose Maria, Costa-Junior, Luciana M, Gonçalves, Hygor N, Araujo, Flavia M M, Paula, Gustavo J, Santos, Renato Chaves Souto, Branco, Kristy, Ou, Klaus H, Kaestner, Leonardo R, Silveira, Camila A M, Oliveira, Antonio C, Boschero, Claudio C, Zoppi, Everardo M, Carneiro

Publikováno v: Life Sciences. 291:120239

Aim Investigate whether inheritance of improved skeletal muscle mitochondrial function and its association with glycemic control are multigenerational benefits of exercise.Male Swiss mice were subjected to 8 weeks of endurance training and mated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff895796986437346103015e38483e43
https://doi.org/10.1016/j.lfs.2021.120239

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Role of NCoR1 in mitochondrial function and energy metabolism

Autor: André Gustavo de Oliveira, Tanes I. Lima, Eveline Soares Menezes, Bianca C. Favero, Rafael Rossi Valentim, Hygor N. Araujo, Leonardo R. Silveira, R. Araújo

Publikováno v: Cell Biology International. 42:734-741

Mitochondrial number and shape are constantly changing in response to increased energy demands. The ability to synchronize mitochondrial pathways to respond to energy fluctuations within the cell is a central aspect of mammalian homeostasis. This dyn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::043e7547ea01351311b0d37cff2de932
https://doi.org/10.1002/cbin.10973

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The MicroRNA miR-696 is regulated by SNARK and reduces mitochondrial activity in mouse skeletal muscle through Pgc1α inhibition

Autor: Bruno G. Teodoro, Dawit A. P. Gonçalves, Kawai So, Sarah J. Lessard, Isis do Carmo Kettelhut, Enilza Maria Espreáfico, Leonardo R. Silveira, Laurie J. Goodyear, Luciane C. Alberici, Dimitrius Santiago P.S.F. Guimarães, André L. Queiroz, Hygor N. Araujo, Michael F. Hirshman, Amanda Tomie Ouchida

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Molecular Metabolism, Vol 51, Iss, Pp 101226-(2021)
Molecular Metabolism

Objective MicroRNAs (miRNA) are known to regulate the expression of genes involved in several physiological processes including metabolism, mitochondrial biogenesis, proliferation, differentiation, and cell death. Methods Using “in silico” analys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ac309ab2d58d1d494d13c13eb8600a
https://doi.org/10.1016/j.molmet.2021.101226

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MicroRNA miR-222 mediates pioglitazone beneficial effects on skeletal muscle of diet-induced obese mice

Autor: Tanes Imamura de Lima, Bruna Araújo dos Santos, Leonardo R. Silveira, Érica de Sousa, Mariana de Mendonça, Ailma Oliveira da Paixão, Alexandre R. Spagnol, Hygor N. Araujo, Gilson Masahiro Murata, Dimitrius Santiago P.S.F. Guimarães, Alice Cristina Rodrigues

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Pioglitazone belongs to the class of drugs thiazolidinediones (TZDs) and is an oral hypoglycemic drug, used in the treatment of type 2 diabetes, which improves insulin sensitivity in target tissues. Adipose tissue is the main target of pioglitazone,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4133fed5a64f42f6d61ffb86945e90
https://pubmed.ncbi.nlm.nih.gov/31770568

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