Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Hyeonyeong Im"'
Autor:
Yoon Keun Cho, Young Cheol Yoon, Hyeonyeong Im, Yeonho Son, Minsu Kim, Abhirup Saha, Cheoljun Choi, Jaewon Lee, Sumin Lee, Jae Hyun Kim, Yun Pyo Kang, Young-Suk Jung, Hong Koo Ha, Je Kyung Seong, James G. Granneman, Sung Won Kwon, Yun-Hee Lee
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Dysregulation of plasmalogen metabolism in adipose tissue is associated with metabolic diseases. Here the authors characterize the role of adipocyte TMEM86A as a lysoplasmalogenase and show its deletion is protective against high fat diet induced met
Externí odkaz:
https://doaj.org/article/2c56b34324264a9f91f13814bde9ec28
Publikováno v:
Nutrition & Metabolism, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Adipose tissue thermogenesis is a potential therapeutic target to increase energy expenditure and thereby combat obesity. The aim of the present study was to investigate the thermogenic and anti-obesity effects of heat-transformed
Externí odkaz:
https://doaj.org/article/63b17b96cd6d48a8aed0df0808fa785f
Autor:
Yeonho Son, Cheoljun Choi, Cheol Song, Hyeonyeong Im, Yoon Keun Cho, Ju Seung Son, Sungug Joo, Yoonjoe Joh, Young Jae Lee, Je Kyung Seong, Yun-Hee Lee
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Cell death-inducing DNA fragmentation factor-like effector A (CIDEA) is a lipid droplet-associated protein and is a known marker of the thermogenic capacity of brown/beige adipocytes. To monitor the expression of CIDEA in live mice in a non-
Externí odkaz:
https://doaj.org/article/b8ad4613a74f4a8b8b944e3624538d61
Autor:
Kyungmin Kim, Hyeonyeong Im, Yeonho Son, Minjae Kim, Sushil Kumar Tripathi, Lak Shin Jeong, Yun-Hee Lee
Publikováno v:
International Journal of Obesity. 46:2128-2136
Background and objectives A2A adenosine receptor (A2AAR)-mediated signaling in adipose tissues has been investigated as a potential target for obesity-related metabolic diseases. LJ-4378 has been developed as a dual-acting ligand with A2AAR agonist a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3241ff05529ce55685550ac746416dc
https://doi.org/10.1038/s41366-022-01224-x
https://doi.org/10.1038/s41366-022-01224-x
Autor:
Juhyeong Han, Young Suk Jung, Ji Hyun Park, Abhirup Saha, James G. Granneman, Minsu Kim, Jeanho Yun, Sangkyu Lee, Cheoljun Choi, Kyung-Min Kim, Yeonho Son, Eun Ju Bae, Yoon Keun Cho, Yun Hee Lee, Doeun Kim, Hyeonyeong Im, Mi-Ock Lee, Je Kyung Seong
Publikováno v:
Nature Metabolism. 3:428-441
Obesity reduces adipocyte mitochondrial function, and expanding adipocyte oxidative capacity is an emerging strategy to improve systemic metabolism. Here, we report that serine/threonine-protein kinase 3 (STK3) and STK4 are key physiological suppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d64e3097e6cee2e9f518d62414f7fb2
https://doi.org/10.1038/s42255-021-00362-2
https://doi.org/10.1038/s42255-021-00362-2
Publikováno v:
Archives of Pharmacal Research
The high incidence of obesity has increased the need to discover new therapeutic targets to combat obesity and obesity-related metabolic diseases. Obesity is defined as an abnormal accumulation of adipose tissue, which is one of the major metabolic o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28db2dcc25db7532e1cab164a1def7c8
http://europepmc.org/articles/PMC7907040
http://europepmc.org/articles/PMC7907040
Publikováno v:
Nutritionmetabolism. 19(1)
Background Adipose tissue thermogenesis is a potential therapeutic target to increase energy expenditure and thereby combat obesity. The aim of the present study was to investigate the thermogenic and anti-obesity effects of heat-transformed green te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc06fd260b09f090152bf1077ab923a0
https://pubmed.ncbi.nlm.nih.gov/35241108
https://pubmed.ncbi.nlm.nih.gov/35241108
Autor:
Yeonho Son, Cheoljun Choi, Abhirup Saha, Ji-Hyun Park, Hyeonyeong Im, Yoon Keun Cho, Je Kyung Seong, Rayanne B. Burl, Elizabeth A. Rondini, James G. Granneman, Yun-Hee Lee
Publikováno v:
Metabolism: clinical and experimental. 130
The mobilization and catabolism of lipid energy is a central function of adipocytes that is under the control of the β-adrenergic signaling pathway, and defects in β-adrenergic signaling in adipocytes have been linked to obesity and obesity-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5418b8a93164d5fa20ad5f983cac68c
https://pubmed.ncbi.nlm.nih.gov/35150731
https://pubmed.ncbi.nlm.nih.gov/35150731
Autor:
Minsu Kim, Yeonho Son, Kyung-Min Kim, Je Kyung Seong, Jin Young Kim, Jung Weon Lee, Yun Hee Lee, Yoon Keun Cho, Hyeonyeong Im, Abhirup Saha, Juhyeong Han, Cheoljun Choi
Publikováno v:
Diabetes
Transmembrane 4 L six family member 5 (TM4SF5) functions as a sensor for lysosomal arginine levels and activates the mammalian target of rapamycin complex 1 (mTORC1). While the mTORC1 signaling pathway plays a key role in adipose tissue metabolism, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18818f97defb251a4d157fb485b135e4
https://doi.org/10.2337/figshare.14831082.v1
https://doi.org/10.2337/figshare.14831082.v1
Autor:
Cheoljun Choi, Yeonho Son, Young Jae Lee, Yoonjoe Joh, Yun Hee Lee, Cheol Song, Hyeonyeong Im, Sungug Joo, Ju Seung Son, Je Kyung Seong, Yoon Keun Cho
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Cell death-inducing DNA fragmentation factor-like effector A (CIDEA) is a lipid droplet-associated protein and is a known marker of the thermogenic capacity of brown/beige adipocytes. To monitor the expression of CIDEA in live mice in a non-invasive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5019146a223362311c40c392fdaccad7
https://pubmed.ncbi.nlm.nih.gov/34531447
https://pubmed.ncbi.nlm.nih.gov/34531447