Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hyeongtaek, Lim"'
Autor:
Zoric, Marija R., Basera, Pooja, Palmer, Levi D., Aitbekova, Aisulu, Powers-Riggs, Natalia, Hyeongtaek Lim, Wenhui Hu, Garcia-Esparza, Angel T., Sarker, Hori, Abild-Pedersen, Frank, Atwater, Harry A., Cushing, Scott K., Bajdich, Michal, Cordones, Amy A.
Publikováno v:
ACS Nano; 7/30/2024, Vol. 18 Issue 30, p19538-19548, 11p
Autor:
Marco E. Reinhard, Michael W. Mara, Thomas Kroll, Hyeongtaek Lim, Ryan G. Hadt, Roberto Alonso-Mori, Matthieu Chollet, James M. Glownia, Silke Nelson, Dimosthenis Sokaras, Kristjan Kunnus, Tim Brandt van Driel, Robert W. Hartsock, Kasper S. Kjaer, Clemens Weninger, Elisa Biasin, Leland B. Gee, Keith O. Hodgson, Britt Hedman, Uwe Bergmann, Edward I. Solomon, Kelly J. Gaffney
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
The dissociation mechanism of the heme axial ligand in heme proteins is not yet fully understood. The authors investigate the photodissociation dynamics of the bond between heme Fe and methionine S in ferrous cytochrome c using femtosecond time-resol
Externí odkaz:
https://doaj.org/article/b36cfbe98c1e409a802196ff2da67f18
Autor:
Keith O. Hodgson, Maxime A. Siegler, Markus Lerch, Kenneth D. Karlin, Wesley J. Transue, Jung Yoon C. Lee, Britt Hedman, Siegfried Schindler, Adam Neuba, Patrick Josephs, Ryan E. Cowley, Mayukh Bhadra, Hyeongtaek Lim, Gerald Henkel, Edward I. Solomon
Publikováno v:
J Am Chem Soc
The central role of cupric superoxide intermediates proposed in hormone and neurotransmitter biosynthesis by noncoupled binuclear copper monooxygenases like dopamine-β-monooxygenase has drawn significant attention to the unusual methionine ligation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587901fb9cf5b97346398fce7589fa13
https://doi.org/10.1021/jacs.1c00260
https://doi.org/10.1021/jacs.1c00260
Autor:
Kristjan Kunnus, Hyeongtaek Lim, Thomas Kroll, Robert W. Hartsock, Dimosthenis Sokaras, Britt Hedman, Leland B. Gee, Kelly J. Gaffney, Silke Nelson, Clemens Weninger, James M. Glownia, Michael W. Mara, Ryan G. Hadt, Elisa Biasin, Tim Brandt van Driel, Uwe Bergmann, Edward I. Solomon, Marco Reinhard, Keith O. Hodgson, Matthieu Chollet, Kasper S. Kjær, Roberto Alonso-Mori
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature Communications
Nature Communications
The dynamics of photodissociation and recombination in heme proteins represent an archetypical photochemical reaction widely used to understand the interplay between chemical dynamics and reaction environment. We report a study of the photodissociati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5caaefb3f747ff4fc4d9473dc120a0e3
https://doaj.org/article/b36cfbe98c1e409a802196ff2da67f18
https://doaj.org/article/b36cfbe98c1e409a802196ff2da67f18
Autor:
Julien Lafrance-Vanasse, Mason J. Appel, Hyeongtaek Lim, Carolyn R. Bertozzi, Chi Lin Tsai, John A. Tainer, Katlyn K. Meier, Britt Hedman, Edward I. Solomon, Keith O. Hodgson
Publikováno v:
Proceedings of the National Academy of Sciences. 116:5370-5375
The formylglycine-generating enzyme (FGE) is required for the posttranslational activation of type I sulfatases by oxidation of an active-site cysteine to C α -formylglycine. FGE has emerged as an enabling biotechnology tool due to the robust utilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d9bf00a1e0426ecfeea9735473642e7
https://doi.org/10.1073/pnas.1818274116
https://doi.org/10.1073/pnas.1818274116
Autor:
Michael L. Baker, Hyeongtaek Lim, Dalia R Biswas, Dimosthenis Sokaras, Britt Hedman, David M. Dooley, Maxime A. Siegler, Mayukh Bhadra, Kenneth D. Karlin, Thomas Kroll, Sunghee Kim, Keith O. Hodgson, Tsu-Chien Weng, Ryan E. Cowley, Edward I. Solomon
Publikováno v:
Inorg Chem
Cu(I) active sites in metalloproteins are involved in O(2) activation, but their O(2) reactivity is difficult to study due to the Cu(I) d(10) closed shell which precludes the use of conventional spectroscopic methods. Kβ X-ray emission spectroscopy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef041baaa7d4d55479b69284c1d3734
https://europepmc.org/articles/PMC7799175/
https://europepmc.org/articles/PMC7799175/
Autor:
Britt Hedman, Keith O. Hodgson, Kenneth D. Karlin, Savita Sharma, Pierre Moënne-Loccoz, Hirotoshi Matsumura, Andrew W. Schaefer, Hyeongtaek Lim, Edward I. Solomon
Publikováno v:
Journal of the American Chemical Society. 139:17421-17430
Peroxynitrite (−OON═O, PN) is a reactive nitrogen species (RNS) which can effect deleterious nitrative or oxidative (bio)chemistry. It may derive from reaction of superoxide anion (O2•–) with nitric oxide (·NO) and has been suggested to form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cbf970b2aebe98403518d14ac687b6d
https://doi.org/10.1021/jacs.7b08468
https://doi.org/10.1021/jacs.7b08468
Autor:
Dimosthenis Sokaras, Edward I. Solomon, Hyeongtaek Lim, Robert W. Hartsock, Britt Hedman, Uwe Bergmann, Keith O. Hodgson, Kelly J. Gaffney, Michael W. Mara, Silke Nelson, James M. Glownia, Kristjan Kunnus, Marco Reinhard, Ryan G. Hadt, Roberto Alonso-Mori, Matthieu Chollet, Thomas Kroll
Publikováno v:
Science. 356:1276-1280
Sulfur's balancing act in cytochrome c Cytochrome c enzymes have two distinct functions that depend on the position of a methionine residue. When the sulfur in the methionine side chain coordinates with iron in the enzyme's active site, the protein i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a6a5e42bd78469dee4f2561cba8784
https://doi.org/10.1126/science.aam6203
https://doi.org/10.1126/science.aam6203
Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O
Autor:
Mason J, Appel, Katlyn K, Meier, Julien, Lafrance-Vanasse, Hyeongtaek, Lim, Chi-Lin, Tsai, Britt, Hedman, Keith O, Hodgson, John A, Tainer, Edward I, Solomon, Carolyn R, Bertozzi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(12)
The formylglycine-generating enzyme (FGE) is required for the posttranslational activation of type I sulfatases by oxidation of an active-site cysteine to C(α)-formylglycine. FGE has emerged as an enabling biotechnology tool due to the robust utilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f0633c33169343265d07d7e8650615c8
https://pubmed.ncbi.nlm.nih.gov/30824597
https://pubmed.ncbi.nlm.nih.gov/30824597
Autor:
Savita K, Sharma, Andrew W, Schaefer, Hyeongtaek, Lim, Hirotoshi, Matsumura, Pierre, Moënne-Loccoz, Britt, Hedman, Keith O, Hodgson, Edward I, Solomon, Kenneth D, Karlin
Publikováno v:
Journal of the American Chemical Society. 139(48)
Peroxynitrite (−OON═O, PN) is a reactive nitrogen species (RNS) which can effect deleterious nitrative or oxidative (bio)chemistry. It may derive from reaction of superoxide anion (O2•−) with nitric oxide (·NO) and has been suggested to form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::962ee803d911f07bf298e137e3151953
https://pubmed.ncbi.nlm.nih.gov/29091732
https://pubmed.ncbi.nlm.nih.gov/29091732