Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Hyeongsun Moon"'
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 4, Pp 538-547 (2020)
Cancer: Inflammatory enzyme linked to skin and esophageal tumors Drugs that block a pro-inflammatory enzyme implicated in cancer initiation and progression could help suppress the development of skin and esophageal cancers that arise from abnormal sq
Externí odkaz:
https://doaj.org/article/1e006bd90b4f418c8b2ad19d12b2d899
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Cellular extrinsic environmental factors contribute to tumour development. Here, the authors show that gastric acid stress stimulates tumour formation from a defined tumour-competent Krt5 + /Krt15 + foregut basal progenitor cell population.
Externí odkaz:
https://doaj.org/article/7869f89b2952464bb4c94fa9d186093f
Autor:
Hyeongsun Moon, Andrew C. White
Publikováno v:
Molecular & Cellular Oncology, Vol 5, Iss 2 (2018)
The relationship between melanocyte stem cells (MCSCs) and melanoma has been unclear. We recently demonstrated that melanoma-prone MCSCs are able to initiate cutaneous melanoma following stem cell activation through ultraviolet-B (UVB) exposure or na
Externí odkaz:
https://doaj.org/article/f4536e68cac447fdbf46198ccefd3c86
Autor:
Kerry L. Inder, Jayde E. Ruelcke, Lara Petelin, Hyeongsun Moon, Eunju Choi, James Rae, Antje Blumenthal, Dietmar Hutmacher, Nicholas A. Saunders, Jennifer L. Stow, Robert G. Parton, Michelle M. Hill
Publikováno v:
Journal of Extracellular Vesicles, Vol 3, Iss 0, Pp 1-14 (2014)
Background: Tumour-derived extracellular vesicles (EVs) play a role in tumour progression; however, the spectrum of molecular mechanisms regulating EV secretion and cargo selection remain to be fully elucidated. We have reported that cavin-1 expressi
Externí odkaz:
https://doaj.org/article/164358b6992a4288a8cbaf67ae06edd9
Publikováno v:
Experimental Dermatology. 28:83-85
Sirt5 is known to functionally regulate mitochondrial proteins by altering posttranslational modifications, including lysine desuccinylation. While roles for Sirt5 as either a tumor promoter or suppressor, or in chemoresistance, have been implicated
Publikováno v:
The Journal of Veterinary Medical Science
Reduction in glomerular filtration rate (GFR) is a common complication in advanced stages of heart failure (HF). The convenient and precise assessment for GFR would be useful for early detection of renal impairment in HF dogs. Our hypothesis of this
Publikováno v:
The Journal of investigative dermatology. 140(8)
Publikováno v:
Journal of visualized experiments : JoVE. (148)
Cutaneous melanoma is well known as the most aggressive skin cancer. Although the risk factors and major genetic alterations continue to be documented with increasing depth, the incidence rate of cutaneous melanoma has shown a rapid and continuous in
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature communications, vol 10, iss 1
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature communications, vol 10, iss 1
The effective prevention of tumor initiation, especially for potentially inoperable tumors, will be beneficial to obtain an overall higher quality of our health and life. Hence, thorough understanding of the pathophysiological mechanisms of early tum
Publikováno v:
Cancer Research. 80:PR08-PR08
Cutaneous melanoma is the most lethal form of skin cancer. However, the molecular mechanisms and environmental factors that can promote melanoma initiation and development from skin without an identified precursor lesion are not well defined. In thes