Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hyeon-Soo Jang"'
Autor:
Jeong Geun Kim, Jong-Min Yoon, Je-Min Koo, Myong-Jae Lee, Ju-Young Jung, Jae-Hoon Kang, Hyeon-Soo Jang, Hee-Yeol Lee, Kyung-Mi An, Soobong Park, Hong-Sub Lee
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:3148-3152
We have previously reported amidopiperidine derivatives as a novel peptide deformylase (PDF) inhibitor and evaluated its antibacterial activity against Gram-positive bacteria, but poor pharmacokinetic profiles have resulted in low efficacy in in vivo
Autor:
Jong-Su Yoo, Jiyoung Kim, Hyuk-Sang Kwon, Jongmin Yoon, Seung-Woo Yeon, Jae-Hoon Kang, Hyeon-Soo Jang, Jong-Hee Ko
Publikováno v:
Pharmaceutical Biology. 53:563-570
The rhizome of Polygonatum sibiricum Redoute (Liliaceae) has long been used to treat diabetes-associated complications. However, the pharmacological mechanism of P. sibiricum on metabolic disorders is not clear.This study investigates the effect of a
Autor:
Hyun Ju Song, Uy Dong Sohn, Hyeon Soo Jang, Sang Soo Sim, Dong-Seok Kim, Sun Young Park, Fa Yong Chung
Publikováno v:
Archives of pharmacal research. 31(11)
Sphingosine 1-phosphate (S1P) is a bioactive lipid, stored and released from activated platelets, macrophages, and other mammalian cells. We previously reported that S1P induces esophageal smooth muscle contraction in freshly isolated intact cells. H
Autor:
Ji-Yeon Kim, Hyun Chae Jung, Dong-Ho Lee, Jung Won Lee, Nayoung Kim, Yoon Jin Choi, Hyeon Soo Jang, Ryoung Hee Nam
Publikováno v:
Gastroenterology. 144:S-324
Abstract 2768: IDH1057, A novel, synthetic, small molecule inhibitor of heat shock protein 90(Hsp90)
Autor:
Soo-Jung Hong, Hyeon-Soo Jang, Jin-Sun Kwon, An-Na Moon, Seung-Woo Yeon, Joon-Tae Park, Hong-Sub Lee, Jae-Hoon Kang, Jin-Ah Jeong, Kwon Sung-Wook, Myong-Jae Lee
Publikováno v:
Cancer Research. 72:2768-2768
Backgroud: The molecular chaperone Heat shock protein 90(Hsp90) governs the stabilization and activity of an array of over 100 ‘client proteins’, many of which are key signaling molecules involved in cell proliferation, survival, and transformati
Publikováno v:
Gastroenterology. 136:A-442