Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Hyeon-Ok Jin"'
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-10 (2021)
Abstract Amino acid availability is sensed by various signaling molecules, including general control nonderepressible 2 (GCN2) and mechanistic target of rapamycin complex 1 (mTORC1). However, it is unclear how these sensors are associated with cancer
Externí odkaz:
https://doaj.org/article/1f5af1fef3a44d8a8f236de5a2388f04
Autor:
Se-Kyeong Jang, Sung-Eun Hong, Da-Hee Lee, Ji-Young Kim, Ji Yea Kim, Sang-Kyu Ye, Jungil Hong, In-Chul Park, Hyeon-Ok Jin
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)
Externí odkaz:
https://doaj.org/article/6989e401dc1c428eb4adee3e6abecea0
Autor:
Se-Kyeong Jang, Sung-Eun Hong, Da-Hee Lee, Ji-Young Kim, Ji Yea Kim, Sang-Kyu Ye, Jungil Hong, In-Chul Park, Hyeon-Ok Jin
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Although the major anticancer effect of metformin involves AMPK-dependent or AMPK-independent mTORC1 inhibition, the mechanisms of action are still not fully understood. Methods To investigate the molecular mechanisms underlying t
Externí odkaz:
https://doaj.org/article/6c533ff3e00745a889cf0d8f9419240f
Autor:
Gyeongmi Kim, Se-Kyeong Jang, Yu Jin Kim, Hyeon-Ok Jin, Seunghee Bae, Jungil Hong, In-Chul Park, Jae Ho Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8761 (2022)
Ovarian cancer is a carcinoma that affects women and that has a high mortality rate. Overcoming paclitaxel resistance is important for clinical application. However, the effect of amino acid metabolism regulation on paclitaxel-resistant ovarian cance
Externí odkaz:
https://doaj.org/article/222750bcf53d49f7856c4331f2b3c4a3
Autor:
YU JIN KIM, SE-KYEONG JANG, GYEONGMI KIM, SUNG-EUN HONG, CHAN SUB PARK, MIN-KI SEONG, HYUN-AH KIM, KWANG SEOK KIM, CHUN-HO KIM, KI SOO PARK, JUNGIL HONG, HYEON-OK JIN, IN-CHUL PARK
Publikováno v:
Anticancer Research. 43:1973-1980
Autor:
Se Hee Ahn, Se-Kyeong Jang, Yu Jin Kim, Gyeongmi Kim, Ki Soo Park, Hyeon-Ok Jin, In-Chul Park
TXNIP is an essential regulator of cellular metabolism, including glucose homeostasis, fatty acid synthesis, cholesterol accumulation, and is implicated in metabolic diseases such as obesity, type 2 diabetes, and atherosclerosis. However, how TXNIP e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0111ee697a3de573a558064907af9d28
https://doi.org/10.21203/rs.3.rs-2915490/v1
https://doi.org/10.21203/rs.3.rs-2915490/v1
Autor:
Yu Jin, Kim, Sung-Eun, Hong, Se-Kyeong, Jang, Ki Soo, Park, Chun-Ho, Kim, In-Chul, Park, Hyeon-Ok, Jin
Publikováno v:
Anticancer Research. 42:3475-3481
Metformin is a widely used drug for type 2 diabetes mellitus and has recently attracted broad attention for its therapeutic effects on many cancers. This study aimed to investigate the molecular mechanism of metformin's anticancer activity.Cell viabi
Autor:
Seok-Il Hong, In-Chul Park, Chang-Hun Rhee, Myung-Jin Park, Young-Joon Hong, Su-Jae Lee, Doo-Hyun Yoo, Tae-Boo Choe, Sung-Keum Seo, Hyeon-Ok Jin, Sang-Hyeok Woo, Hansoo Lee, Sungkwan An, Hyung-Chahn Lee
Supplementary Data from Activation of Epidermal Growth Factor Receptor and Its Downstream Signaling Pathway by Nitric Oxide in Response to Ionizing Radiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510f40069aa0e55300e1975cdfef897c
https://doi.org/10.1158/1541-7786.22516807
https://doi.org/10.1158/1541-7786.22516807
Autor:
Seok-Il Hong, In-Chul Park, Chang-Hun Rhee, Myung-Jin Park, Young-Joon Hong, Su-Jae Lee, Doo-Hyun Yoo, Tae-Boo Choe, Sung-Keum Seo, Hyeon-Ok Jin, Sang-Hyeok Woo, Hansoo Lee, Sungkwan An, Hyung-Chahn Lee
Epidermal growth factor receptor (EGFR) is activated by ionizing radiation (IR), but the molecular mechanism for this effect is unknown. We have found that intracellular generation of nitric oxide (NO) by NO synthase (NOS) is required for the rapid a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc8ad12cdb33d7c5ac051fe2bb54c086
https://doi.org/10.1158/1541-7786.c.6541492
https://doi.org/10.1158/1541-7786.c.6541492
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-10 (2021)
Cell Death & Disease
Cell Death & Disease
Amino acid availability is sensed by various signaling molecules, including general control nonderepressible 2 (GCN2) and mechanistic target of rapamycin complex 1 (mTORC1). However, it is unclear how these sensors are associated with cancer cell sur