Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Hyeon Sook Koo"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1639 (2021)
The extracellular matrix (ECM) is important for normal development and disease states, including inflammation and fibrosis. To understand the complex regulation of ECM, we performed a suppressor screening using Caenorhabditis elegans expressing the m
Externí odkaz:
https://doaj.org/article/20b4ec8777af478a9fe72cfe17413e5b
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123865 (2015)
PHF8 is a JmjC domain-containing histone demethylase, defects in which are associated with X-linked mental retardation. In this study, we examined the roles of two PHF8 homologs, JMJD-1.1 and JMJD-1.2, in the model organism C. elegans in response to
Externí odkaz:
https://doaj.org/article/0a9b1f67792d443fa2baca63ca032bd8
Publikováno v:
The FEBS Journal. 287:1101-1115
Deficiency of either of the two homologs of poly(ADP-ribose) glycohydrolase (PARG), PARG-1 and PARG-2, in Caenorhabditis elegans leads to hypersensitivity to ionizing radiation (IR). In the germ cells of parg-2 mutant worms, the dissipation of recomb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d932d8228fef21577ab37d6d970fdd42
https://doi.org/10.1111/febs.15082
https://doi.org/10.1111/febs.15082
Publikováno v:
DNA Repair. 75:18-28
A missense mutation in C. elegans RAD-54, a homolog of RAD54 that operates in the homologous recombination (HR) pathway, was found to decrease ATPase activity in vitro. The hypomorphic mutation caused hypersensitivity of C. elegans germ cells to doub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992d88206c9f8328c4d7c51071e7972a
https://doi.org/10.1016/j.dnarep.2019.01.007
https://doi.org/10.1016/j.dnarep.2019.01.007
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1639, p 1639 (2021)
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1639, p 1639 (2021)
The extracellular matrix (ECM) is important for normal development and disease states, including inflammation and fibrosis. To understand the complex regulation of ECM, we performed a suppressor screening using Caenorhabditis elegans expressing the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147f267cf254689fe4dd4e525dd7caaf
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64028 (2013)
53BP1 contributes to activation of the G2/M checkpoint downstream of ATM and MDC1 in response to ionizing radiation and promotes nonhomologous end-joining (NHEJ) in mammalian cells. In order to determine whether the cellular activities of 53BP1 are c
Externí odkaz:
https://doaj.org/article/f7832ebe0a4b4053b04599b627367b72
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60071 (2013)
The Fanconi anemia (FA) pathway recognizes interstrand DNA crosslinks (ICLs) and contributes to their conversion into double-strand DNA breaks, which can be repaired by homologous recombination. Seven orthologs of the 15 proteins associated with Fanc
Externí odkaz:
https://doaj.org/article/2e0878428fe4428591b1af4799ef4b68
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
Upon sensing starvation stress, Caenorhabditis elegans larvae (L2d) elicit two seemingly opposing behaviors to escape from the stressful condition: food-seeking roaming mediated by the opioid peptide NLP-24 and dauer formation mediated by pheromones.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9deedf9b0daa5539f3e0769f39a360
https://doi.org/10.1038/s41598-020-64567-3
https://doi.org/10.1038/s41598-020-64567-3
Publikováno v:
PLoS Genetics, Vol 6, Iss 1, p e1000801 (2010)
WRN-1 is the Caenorhabditis elegans homolog of the human Werner syndrome protein, a RecQ helicase, mutations of which are associated with premature aging and increased genome instability. Relatively little is known as to how WRN-1 functions in DNA re
Externí odkaz:
https://doaj.org/article/5cd192ff362548c0a6f574257acb8155
Autor:
Jin Sun Ryu, Hyeon Sook Koo
Publikováno v:
Gerontology. 62:296-303
Werner syndrome protein (WRN) is unusual among RecQ family DNA helicases in having an additional exonuclease activity. WRN is involved in the repair of double-strand DNA breaks via the homologous recombination and nonhomologous end joining pathways,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38d4b7dd0d443f579fec9b4309604b03
https://doi.org/10.1159/000439200
https://doi.org/10.1159/000439200