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Molecular identification of ALDH1A1 and SIRT2 in the astrocytic putrescine-to-GABA metabolic pathway
Autor:
Mridula Bhalla, Jeong Im Shin, Yeon Ha Ju, Yongmin Mason Park, Seonguk Yoo, Hyeon Beom Lee, C Justin Lee
GABA (γ-aminobutyric acid) is the primary inhibitory neurotransmitter in the CNS. In astrocytes, GABA is synthesized by degradation of putrescine by monoamine oxidase B (MAO-B), a process which is known to mediate tonic inhibition of neuronal excita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77e329b59b9221d5beaaa32a8b1cee83
https://doi.org/10.1101/2023.01.11.523573
https://doi.org/10.1101/2023.01.11.523573
