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Autor:
Cynthia Helsabeck, Seth M. Steinberg, Takefumi Komiya, William D. Figg, Guinevere Chun, Marc S. Ballas, Wendy B. Bernstein, Roopa DeChowdhury, Jaclyn LoPiccolo, Joell J. Gills, Hyejeong Root, Shigeru Kawabata, Gideon M. Blumenthal, Phillip A. Dennis, Betsy Morrow, Erin R. Gardner
Publikováno v:
Oncotarget
Nelfinavir is an HIV protease inhibitor being repurposed as an anti-cancer agent in preclinical models and in small oncology trials, yet the MTD of nelfinavir has not been determined. Therefore, we conducted a Phase Ia study to establish the maximum