Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hyeim Jo"'
Autor:
Yeji Byeon, Seung Hee Jung, Daseul Yoon, Seock Yong Kang, Jiyeon Park, Hyeim Jo, Seong-Il Choi, Somyi Park, Seung-chul Lee, Yang Hun Tae, Tae Min Kim, Sung-Yup Cho, Soyeon Kim, Donghyun Ko, Dong-Kyu Kim, Dong-Wan Kim
Publikováno v:
Cancer Research. 82:5477-5477
The L858R activating mutation in Epidermal Growth Factor Receptor (EGFR) accounts for approximately 40% of EGFR-mutant non-small cell lung cancer (NSCLC). These patients receive targeted therapy targeting EGFR mutation. To date all approved EGFR tyro
Autor:
Saegun Kim, Sang Hoon Han, Hyeim Jo, Mijin Jeon, Jong Suk Lee, Neeraj Kumar Mishra, In Su Kim, Hyung Sik Kim, Yongguk Oh, Woo Jung Kim
Publikováno v:
Advanced Synthesis & Catalysis. 359:2396-2401
The rhodium(III)-catalyzed site-selective C−H alkylation of azobenzenes and internal olefins, such as maleimides, maleates and fumarates, followed by reductive intramolecular cyclization is described. A cationic rhodium catalyst in the presence of
Autor:
Byung Mu Lee, Hyo Sun Suh, Sang Hoon Han, Sangil Han, Hyung Sik Kim, Yongguk Oh, Young Hoon Jung, Hyeim Jo, Neeraj Kumar Mishra, In Su Kim
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:2129-2134
The iridium(III)-catalyzed ortho -C–H amidation of benzoic acids with sulfonyl azides is described. These transformations allow the facile generation of N -sulfonyl anthranilic acids, which are known as crucial scaffolds found in biologically activ
Autor:
Hyeim Jo, Jihye Park, Mijin Jeon, Young Hoon Jung, Neeraj Kumar Mishra, Hyunjung Oh, Seok-Yong Lee, In Su Kim, Satyasheel Sharma
Publikováno v:
Tetrahedron. 73:1725-1732
The ruthenium(II)-catalyzed site-selective acylation of indolinic C−H bonds with ethyl glyoxalate is described. A cationic ruthenium catalyst in the presence of copper(II) acetate was found to be an optimal catalytic system for the construction of
Autor:
Jihye Park, Yongguk Oh, Sang Hoon Han, Mijin Jeon, Young Hoon Jung, Hyeim Jo, Neeraj Kumar Mishra, Satyasheel Sharma, Sangil Han, In Su Kim
Publikováno v:
Organic Chemistry Frontiers. 4:241-249
The pyrimidinyl-directed C–H functionalization of indolines with anthranils as amination sources under rhodium(III) catalysis is described. This transformation efficiently provides a range of C7-aminated indoline derivatives with excellent site-sel
Autor:
Satyasheel Sharma, Umasankar De, Neeraj Kumar Mishra, Richa Sachan, Young Hoon Jung, Hyung Sik Kim, In Su Kim, Hyeim Jo, Yongguk Oh
Publikováno v:
The Journal of Organic Chemistry. 82:3359-3367
The rhodium(III)-catalyzed redox-neutral coupling reaction of N-acyl ketimines generated in situ from 3-hydroxyisoindolinones with various activated olefins is described. This approach leads to the synthesis of bioactive spiroisoindolinone derivative
Autor:
Sangil Han, Jihye Park, Satyasheel Sharma, Neeraj Kumar Mishra, Miji Choi, Hyeim Jo, Mijin Jeon, Taejoo Jeong, In Su Kim
Publikováno v:
Advanced Synthesis & Catalysis. 358:2714-2720
The ruthenium(II)- or rhodium(III)-catalyzed pyrimidinyl-directed Grignard-type C−H additions of N-heterocycles with activated aldehydes and ketones are described. A cationic ruthenium catalyst and sodium acetate additive in dichloroethane as solve
Autor:
In Su Kim, Sangil Han, Jihye Park, Sang Hoon Han, Satyasheel Sharma, Neeraj Kumar Mishra, Miji Choi, Taejoo Jeong, Hyeim Jo
Publikováno v:
European Journal of Organic Chemistry. 2016:3611-3618
The rhodium(III)-catalyzed direct C–H functionalization of enol carbamates with a range of maleimides is described. With the assistance of the carbamoyl directing group, this reaction provides biologically relevant succinimide compounds by proceedi
Autor:
Saegun Kim, Neeraj Kumar Mishra, Miji Choi, Hyeim Jo, Satyasheel Sharma, Sangil Han, Jihye Park, Taejoo Jeong, In Su Kim
Publikováno v:
European Journal of Organic Chemistry. 2016:3076-3083
The rhodium(III)-catalyzed tandem C–H olefination and cyclization of benzamides with various alkenes is described. This protocol provides direct access to highly substituted phthalides, which are known as crucial frameworks of biologically active c
Autor:
Young Hoon Jung, Sang Hoon Han, Hyeim Jo, Sangil Han, Taejoo Jeong, Jong Hwan Kwak, Miji Choi, Seok-Yong Lee, Jihye Park, In Su Kim
Publikováno v:
Tetrahedron. 72:571-578
The rhodium(III)-catalyzed mild and site-selective C–H allylation of 2-arylbenzo[d]thiazoles and 2-arylbenzo[d]oxazoles with allylic phosphonates and allylic carbonates is described. This transformation provides an efficient construction of C2-ally