Zobrazeno 1 - 10
of 287
pro vyhledávání: '"Hye-Yun Kim"'
Autor:
Sehyun Chae, Hyun-ju Lee, Ha-Eun Lee, Jieun Kim, Yoo Joo Jeong, Yuxi Lin, Hye Yun Kim, Geoffray Leriche, Rachel S. Ehrlich, Sascha Castro Lingl, Min-Duk Seo, Young-Ho Lee, Jerry Yang, Jae-Ick Kim, Hyang-Sook Hoe
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-34 (2024)
Abstract Background We recently reported that the dopamine (DA) analogue CA140 modulates neuroinflammatory responses in lipopolysaccharide-injected wild-type (WT) mice and in 3-month-old 5xFAD mice, a model of Alzheimer’s disease (AD). However, the
Externí odkaz:
https://doaj.org/article/320a17cb8a82451c8f0b059ff0d03f14
Autor:
Jusung An, Kyeonghwan Kim, Ho Jae Lim, Hye Yun Kim, Jinwoo Shin, InWook Park, Illhwan Cho, Hyeong Yun Kim, Sunghoon Kim, Catriona McLean, Kyu Yeong Choi, YoungSoo Kim, Kun Ho Lee, Jong Seung Kim
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Amyloid-β (Aβ) oligomers are implicated in the onset of Alzheimer’s disease (AD). Herein, quinoline-derived half-curcumin-dioxaborine (Q-OB) fluorescent probe was designed for detecting Aβ oligomers by finely tailoring the hydrophobicit
Externí odkaz:
https://doaj.org/article/b0629641da734999a8efef9bc1a0e7dc
Autor:
Hye Yun Kim, Jieun Lee, Hyun-Jin Kim, Byeong Eun Lee, Jaewook Jeong, Eun Jeong Cho, Hyun-Jun Jang, Kyeong Jin Shin, Min Ji Kim, Young Chan Chae, Seung Eun Lee, Kyungjae Myung, Ja-Hyun Baik, Pann-Ghill Suh, Jae-Ick Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 11, Pp 2357-2375 (2023)
Abstract Dopamine neurons are essential for voluntary movement, reward learning, and motivation, and their dysfunction is closely linked to various psychological and neurodegenerative diseases. Hence, understanding the detailed signaling mechanisms t
Externí odkaz:
https://doaj.org/article/9bf57bd326b342e499039a5360ea2560
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Alzheimer’s disease (AD) is characterized by misfolding, oligomerization, and accumulation of amyloid-β (Aβ) peptides in the brain. Aβ monomers transform into Aβ oligomers, which are toxic species, inducing tau hyperphosphorylation and
Externí odkaz:
https://doaj.org/article/988ddd39b0d24ca9a01eb94167a8e76b
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Pyroglutamate amyloid-β3-42 (AβpE3-42) is an N-terminally truncated and pyroglutamate-modified Aβ peptide retaining highly hydrophobic, amyloidogenic, and neurotoxic properties. In Alzheimer’s disease (AD) patients, AβpE3-42 peptides a
Externí odkaz:
https://doaj.org/article/690a0abc64344c068d6eef27addd9425
Autor:
Hee Yang Lee, Soljee Yoon, Jeong Hwa Lee, Keunwan Park, Youngeun Jung, Illhwan Cho, Donghee Lee, Jisu Shin, Kyeonghwan Kim, Sunmi Kim, Jimin Kim, Koeun Kim, Seung Hoon Han, Seong Muk Kim, Hye Ju Kim, Hye Yun Kim, Ikyon Kim, Young Soo Kim
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-19 (2022)
Abstract Background Aggregated amyloid-β (Aβ) is considered a pathogenic initiator of Alzheimer’s disease (AD), in strong association with tau hyperphosphorylation, neuroinflammation, synaptic dysfunction, and cognitive decline. As the removal of
Externí odkaz:
https://doaj.org/article/4e33b2fd1a2542f2aa38952a5a6ba0d5
Autor:
Taeseong Woo, Hye Yun Kim, Su Yeon Kim, Byungjae Hwang, Cheolwoo Ahn, Seok-Kyu Kwon, Jae-Ick Kim, Jung-Hoon Park
Publikováno v:
APL Photonics, Vol 7, Iss 10, Pp 106106-106106-11 (2022)
Recent advances in biochemistry and optics have enabled observation of the faintest signals from even single molecules. However, although biological samples can have varying degrees of fluorescence expression ranging from a single to thousands of flu
Externí odkaz:
https://doaj.org/article/1aacaef637c94a22b3acda1f20391d02
Autor:
Se Rin Park, Jun Gi Hwang, Sae Im Jeong, Young-Sim Choi, Hyo Jin Min, Hye Yun Kim, Bong-Hoi Choi, Min Kyu Park
Publikováno v:
Translational & Clinical Pharmacology; Mar2024, Vol. 32 Issue 1, p63-72, 10p
Autor:
Sohui Park, Hye Yun Kim, Hyun-A Oh, Jisu Shin, In Wook Park, Soljee Yoon, Dong Ho Woo, YoungSoo Kim
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Alzheimer’s disease (AD) is the most common type of dementia characterized by the abnormal accumulation of amyloid-β (Aβ) in the brain. Aβ misfolding is associated with neuroinflammation and synaptic dysfunction, leading to learning and
Externí odkaz:
https://doaj.org/article/29018fb8699a4f919b6073af5edefb14
Publikováno v:
Advanced Science, Vol 9, Iss 12, Pp n/a-n/a (2022)
Abstract Amyloid‐β (Aβ) deposition in the brain is a primary biomarker of Alzheimer's disease (AD) and Aβ measurement for AD diagnosis mostly depends on brain imaging and cerebrospinal fluid analyses. Blood Aβ can become a reliable surrogate bi
Externí odkaz:
https://doaj.org/article/b2d34a61758f478985c88c3f413659c6