Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Hye-Youn Cho"'
Autor:
Hye-Youn Cho, Xuting Wang, Michelle R. Campbell, Vijayalakshmi Panduri, Silvina Coviello, Mauricio T. Caballero, Brian D. Bennett, Steven R. Kleeberger, Fernando P. Polack, Gaston Ofman, Douglas A. Bell
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-21 (2023)
Abstract Bronchopulmonary dysplasia (BPD) is a prevalent chronic lung disease of prematurity with limited treatment options. To uncover biomarkers of BPD risk, this study investigated epigenetic and transcriptomic signatures of prematurity at birth a
Externí odkaz:
https://doaj.org/article/8cb45c3ead1241fc8305deb96342b095
Autor:
Xuting Wang, Michelle R. Campbell, Hye-Youn Cho, Gary S. Pittman, Suzanne N. Martos, Douglas A. Bell
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-20 (2023)
Abstract Background Tobacco smoking alters the DNA methylation profiles of immune cells which may underpin some of the pathogenesis of smoking-associated diseases. To link smoking-driven epigenetic effects in specific immune cell types with disease r
Externí odkaz:
https://doaj.org/article/2fcb18bf67be4c87ae672d46389e0c9e
Autor:
Gaston Ofman, Mauricio T. Caballero, Damian Alvarez Paggi, Jacqui Marzec, Florencia Nowogrodzki, Hye-Youn Cho, Mariana Sorgetti, Guillermo Colantonio, Alejandra Bianchi, Luis M. Prudent, Nestor Vain, Gonzalo Mariani, Jorge Digregorio, Elba Lopez Turconi, Cristina Osio, Fernanda Galletti, Mariangeles Quiros, Andrea Brum, Santiago Lopez Garcia, Silvia Garcia, Douglas Bell, Marcus H. Jones, Trent E. Tipple, Steven R. Kleeberger, Fernando P. Polack
Publikováno v:
BMC Pediatrics, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Premature birth is a growing and serious public health problem affecting more than one of every ten infants worldwide. Bronchopulmonary dysplasia (BPD) is the most common neonatal morbidity associated with prematurity and infants
Externí odkaz:
https://doaj.org/article/3ff2a31093274717b005d9f4967c448d
Autor:
Mary E. Robbins, Hye-Youn Cho, Jason M. Hansen, Joseph R. Luchsinger, Morgan L. Locy, Markus Velten, Steven R. Kleeberger, Lynette K. Rogers, Trent E. Tipple
Publikováno v:
Redox Biology, Vol 38, Iss , Pp 101797- (2021)
Cellular antioxidants protect against hyperoxic lung injury. The role of the glutathione (GSH) system in lung development and bronchopulmonary dysplasia (BPD) pathogenesis has not been systematically investigated. The current study utilized GSH reduc
Externí odkaz:
https://doaj.org/article/76f985e8ce0849b084f1d19bda16926a
Autor:
Heather L. Vellers, Hye-Youn Cho, Wesley Gladwell, Kevin Gerrish, Janine H. Santos, Gaston Ofman, Laura Miller-DeGraff, T. Beth Mahler, Steven R. Kleeberger
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 760 (2022)
Approximately 1 in 10 newborns are born preterm and require supplemental oxygen (O2) in an extrauterine environment following birth. Supplemental O2 can induce oxidative stress that can impair mitochondrial function, resulting in lung injury and incr
Externí odkaz:
https://doaj.org/article/37b95ba35a3d4e7dad2fc02c2e9396ef
Autor:
Hye-Youn Cho, Laura Miller-DeGraff, Ligon A. Perrow, Wesley Gladwell, Vijayalakshmi Panduri, Fred B. Lih, Steven R. Kleeberger
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1874 (2021)
NRF2 protects against oxidant-associated airway disorders via cytoprotective gene induction. To examine if NRF2 is an important determinant of respiratory syncytial virus (RSV) susceptibility after neonate lung injury, Nrf2-deficient (Nrf2−/−) an
Externí odkaz:
https://doaj.org/article/17dae43bb82341c1b48a3975fc454159
Autor:
Hye-Youn Cho, Anne E. Jedlicka, Frederick H. Chang, Jacqui Marzec, Alison K. Bauer, Steven R. Kleeberger
Publikováno v:
Antioxidants, Vol 10, Iss 9, p 1489 (2021)
Ozone (O3) is the predominant oxidant air pollutant associated with airway inflammation, lung dysfunction, and the worsening of preexisting respiratory diseases. We previously demonstrated the injurious roles of pulmonary immune receptors, tumor necr
Externí odkaz:
https://doaj.org/article/9dc3c50c2d91438d910a53b0197ee3e3
Autor:
Monica High, Hye-Youn Cho, Jacqui Marzec, Tim Wiltshire, Kirsten C. Verhein, Mauricio T. Caballero, Patricio L. Acosta, Jonathan Ciencewicki, Zackary R. McCaw, Lester Kobzik, Laura Miller-DeGraff, Wes Gladwell, David B. Peden, M. Elina Serra, Min Shi, Clarice Weinberg, Oscar Suzuki, Xuting Wang, Douglas A. Bell, Fernando P. Polack, Steven R. Kleeberger
Publikováno v:
EBioMedicine, Vol 11, Iss C, Pp 73-84 (2016)
Background: Respiratory syncytial virus (RSV) is the global leading cause of lower respiratory tract infection in infants. Nearly 30% of all infected infants develop severe disease including bronchiolitis, but susceptibility mechanisms remain unclear
Externí odkaz:
https://doaj.org/article/75df4081aa8d475baa78bd98275d0285
Autor:
Xuting Wang, Michelle R. Campbell, Sarah E. Lacher, Hye-Youn Cho, Ma Wan, Christopher L. Crowl, Brian N. Chorley, Gareth L. Bond, Steven R. Kleeberger, Matthew Slattery, Douglas A. Bell
Publikováno v:
Cell Reports, Vol 15, Iss 4, Pp 830-842 (2016)
The NRF2/sMAF protein complex regulates the oxidative stress response by occupying cis-acting enhancers containing an antioxidant response element (ARE). Integrating genome-wide maps of NRF2/sMAF occupancy with disease-susceptibility loci, we discove
Externí odkaz:
https://doaj.org/article/6732ec0f9ed54ef7b6c73c665f68a24d
Autor:
Hye-Youn Cho, Eun-Jae An
Publikováno v:
JOURNAL OF THE KOREAN SOCIETY DESIGN CULTURE. 27:515-528
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf86ccda0b36834fb8f8e71eb98e598a
https://doi.org/10.18208/ksdc.2021.27.4.515
https://doi.org/10.18208/ksdc.2021.27.4.515