Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Hye-Yeong Nam"'
Autor:
Goo-Young Kim, Ji Yeon Son, So Jin Lee, Sang Woo Jo, Changhoon In, Sang Hoon Kim, Joon Young Park, So-Young Kim, Gyu-Young Moon, Ji-Hye Choi, Suk-Hwan Kim, Minhyuk Yun, Hye Yeong Nam, Helen Cho
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/48aaa91a435d416bae898f6c1ff221fd
Autor:
Minhyuk Yun, Helen Cho, Joon Young Park, Hye Yeong Nam, Goo-Young Kim, Lee So-Jin, Sang Woo Jo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Successful clinical translation of mRNA therapeutics requires an appropriate delivery strategy to overcome instability of mRNA and facilitate cellular uptake into the cells.1 Several lipid based nanoparticle approaches that encapsulate mRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a04635e8e1a9db044587d17c3437cf
https://doaj.org/article/184371bf44f645d4913d4f5ef70bedac
https://doaj.org/article/184371bf44f645d4913d4f5ef70bedac
Autor:
Gyu-Young Moon, Suk-Hwan Kim, Choi Ji-Hye, Ji Yeon Son, Sang Hoon Kim, Joon Young Park, Goo-Young Kim, Helen Cho, Minhyuk Yun, So Young Kim, Chang-Hoon In, So Jin Lee, Hye Yeong Nam, Sang Woo Jo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Oncolytic viro-therapeutics is a promising treatment for cancer. Among the different strains of oncolytic viruses currently being developed, potent cytolytic activity, manageable safety profiles, large genomic capacity for addition of tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963e2ba0f3cdf8dbd98291268de24f64
https://doaj.org/article/48aaa91a435d416bae898f6c1ff221fd
https://doaj.org/article/48aaa91a435d416bae898f6c1ff221fd
Autor:
Chunggu Kim, Boyoung Choi, Kunho Chung, Irfan Ullah, Yan Li, Hye Yeong Nam, Chae-Ok Yun, Sumin Bae, Sun Hwa Kim, Sang-Kyung Lee, Priti Kumar, Kuen Yong Lee
Publikováno v:
Molecular pharmaceutics. 17(4)
Glioblastoma multiforme (GBM) is an aggressive tumor with no curative treatment. The tumor recurrence after resection often requires chemotherapy or radiation to delay the infiltration of tumor remnants. Intracerebral chemotherapies are preferentiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d752535126408d8804968a6ce796037b
https://pubmed.ncbi.nlm.nih.gov/31944768
https://pubmed.ncbi.nlm.nih.gov/31944768
Publikováno v:
Journal of Controlled Release. 158:451-460
As an effort to overcome limits of adenovirus (Ad) as a systemic delivery vector for cancer therapy, we developed a novel system using oncolytic Ad plasmid DNA with two bioreducible polymers: arginine-grafted bioreducible poly(disulfide amine)polymer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9c1f02696e9d9104aaf7c8f11810cf
https://doi.org/10.1016/j.jconrel.2011.12.008
https://doi.org/10.1016/j.jconrel.2011.12.008
Autor:
Sung Wan Kim, Tae-il Kim, Jaesung Kim, Chae-Ok Yun, Pyung-Hwan Kim, Hye Yeong Nam, Min Jung Kim, James W. Yockman
Publikováno v:
Biomaterials. 32:9328-9342
Systemic administration of adenovirus (Ad) vectors is complicated by host immune responses and viral accumulation in the liver, resulting in a short circulatory virus half-life, low efficacy, and host side effects. Ad surface modification is thus req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385a5ad28fed6799a03edf2e231df61d
https://doi.org/10.1016/j.biomaterials.2011.08.066
https://doi.org/10.1016/j.biomaterials.2011.08.066
Autor:
Chae-Ok Yun, Sung Wan Kim, Jaesung Kim, Tae-il Kim, Jihoon Ryu, Pyung-Hwan Kim, Hye Yeong Nam
Publikováno v:
Biomaterials. 32:5158-5166
Even though oncolytic adenovirus (Ad) has been highlighted in the field of cancer gene therapy, transductional targeting and immune privilege still remain difficult challenges. The recent reports have noted the increasing tendency of adenoviral surfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc36ee1ae3f495c7c1d52cf8a52a1a66
https://doi.org/10.1016/j.biomaterials.2011.03.084
https://doi.org/10.1016/j.biomaterials.2011.03.084
Publikováno v:
Biomaterials. 32:5213-5222
The primary cardiomyocyte-specific peptide (PCM) and the cell-penetrating peptide (CPP), HIV-Tat (49-57), were incorporated into the polymer, cystamine bisacrylamide-diaminohexane (CBA-DAH), to increase the delivery of RNAi to target cells, specifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fde050caaed44aa15762843eda573c3
https://doi.org/10.1016/j.biomaterials.2011.03.058
https://doi.org/10.1016/j.biomaterials.2011.03.058
Bioreducible polymer-transfected skeletal myoblasts for VEGF delivery to acutely ischemic myocardium
Autor:
Mei Ou, Hye Yeong Nam, James W. Yockman, Catherine M. Straub, Arlo N. McGinn, Sung Wan Kim, Norman Hu, David A. Bull
Publikováno v:
Biomaterials. 32:942-949
Implantation of skeletal myoblasts to the heart has been investigated as a means to regenerate and protect the myocardium from damage after myocardial infarction. While several animal studies utilizing skeletal myoblasts have reported positive findin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce6febd3060907f8c82b2c285aa3fdb
https://doi.org/10.1016/j.biomaterials.2010.09.061
https://doi.org/10.1016/j.biomaterials.2010.09.061
Publikováno v:
Biomaterials. 31:8081-8087
A cardiomyocyte-targeted Fas siRNA delivery system was developed using primary cardiomyocyte (PCM) specific peptide-modified polymers with high transfection efficiency and low cytotoxicity. Primary cardiomyocyte (PCM) specific peptide, selected by ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80645890f7c5317760701b96b740dba
https://doi.org/10.1016/j.biomaterials.2010.07.025
https://doi.org/10.1016/j.biomaterials.2010.07.025