Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Hye-Sook Han"'
Publikováno v:
Diabetes & Metabolism Journal, Vol 44, Iss 4, Pp 498-508 (2020)
Cyclic adenosine monophosphate (cAMP) signaling is critical for regulating metabolic homeostasis in mammals. In particular, transcriptional regulation by cAMP response element-binding protein (CREB) and its coactivator, CREB-regulated transcription c
Externí odkaz:
https://doaj.org/article/6ac98d4a1f4b4e438213d61bb9984528
Autor:
Hye-Sook Han, Sang Gyune Kim, Young Seok Kim, Si-Hyong Jang, Yongmin Kwon, Dahee Choi, Tom Huh, Eunyoung Moon, Eunyong Ahn, Je Kyung Seong, Hee-Seok Kweon, Geum-Sook Hwang, Dae Ho Lee, Kae Won Cho, Seung-Hoi Koo
Publikováno v:
Molecular Metabolism, Vol 55, Iss , Pp 101402- (2022)
Objective: Diet-induced obesity is often associated with nonalcoholic fatty liver disease (NAFLD), which instigates severe metabolic disorders, including cirrhosis, hepatocellular carcinoma, and type 2 diabetes. We have shown that hepatic depletion o
Externí odkaz:
https://doaj.org/article/7b787322d9f843c4ad7ec37dc28d4bb7
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
CREB-regulated transcription coactivator 2, CRTC2, has been associated with regulation of glucose and lipid homeostasis. Here Han et al. show that Creb/Crtc2 modulates lipid and glucose metabolism by inhibiting the expression of mi-R34 that, in turn,
Externí odkaz:
https://doaj.org/article/95fe6a39c576491889a4a394d3aca70c
Publikováno v:
Endocrinology and Metabolism, Vol 29, Iss 4, Pp 435-440 (2014)
Glucose homeostasis is tightly controlled by the regulation of glucose production in the liver and glucose uptake into peripheral tissues, such as skeletal muscle and adipose tissue. Under prolonged fasting, hepatic gluconeogenesis is mainly responsi
Externí odkaz:
https://doaj.org/article/6e949200c7b2479781ed086355a88740
Autor:
Sung Hee Lim, Keun-Wook Lee, Jae-Joon Kim, Hyeon-Su Im, In-Ho Kim, Hye Sook Han, Dong-Hoe Koo, Jang Ho Cho, Chi Hoon Maeng, Min-Young Lee, Hyo Jin Lee, Jwa Hoon Kim, Sang Gon Park, Joo Young Jung, Seong-Hoon Shin, Ki Hyang Kim, Hyeyeong Kim, So Yeon Oh, Minsu Kang, Minkyu Jung, Sun Young Rha
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Immune checkpoint inhibitor (ICI) or irinotecan-based chemotherapy is frequently used after failure of second-line paclitaxel plus ramucirumab treatment for patients with locally advanced unresectable or metastatic advanced gastri
Externí odkaz:
https://doaj.org/article/9274e12fab6e4e7e902af4a321c8f49d
Autor:
Minkwan Cho, Eunkyung Park, Yong-Pyo Lee, Hongsik Kim, Hee Sue Park, Hee Kyung Kim, Yaewon Yang, Jihyun Kwon, Ki Hyeong Lee, Hye Sook Han
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Esophagogastric and pancreaticobiliary cancers are associated with chronic blood loss, poor nutrition, and surgical interventions that interfere with iron absorption. Patients with these cancers often have a higher incidence of chemothera
Externí odkaz:
https://doaj.org/article/2a6d9839eeb441868dd97ae3dfbe9621
Autor:
Hongsik Kim, Jinah Chu, In-Gu Do, Yong-Pyo Lee, Hee Kyung Kim, Yaewon Yang, Jihyun Kwon, Ki Hyeong Lee, Chinbayar Batochir, Eunji Jo, Kyo Rim Kim, Hye Sook Han
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposePancreatic ductal adenocarcinoma (PDAC) is an aggressive tumor with a poor prognosis that poses challenges for diagnosis using traditional tissue-based techniques. DNA methylation alterations have emerged as potential and promising biomarkers
Externí odkaz:
https://doaj.org/article/59fd287f32d0414493cbfee5c78448a3
Autor:
Seung-Myoung Son, Jieun Yun, Dong-Wook Kim, Young-Suk Jung, Sang-Bae Han, Yong Hee Lee, Hye Sook Han, Chang Gok Woo, Ho-Chang Lee, Ok-Jun Lee
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Non-coding microRNAs (miRNAs) play critical roles in tumor progression and hold great promise as therapeutic agents for multiple cancers. MicroRNA 29a (miR-29a) is a tumor suppressor miRNA that inhibits cancer cell growth and tumo
Externí odkaz:
https://doaj.org/article/9aae04380f7c4f979df18e66f5383499
Autor:
Hye Sook Han1, Keun-Wook Lee2 imdoctor@snu.ac.kr
Publikováno v:
Journal of Gastric Cancer. Jan2024, Vol. 24 Issue 1, p4-28. 25p.
Autor:
Hye Sook Han, Kyoung Eun Lee, Young Ju Suh, Hee-Jung Jee, Bum Jun Kim, Hyeong Su Kim, Keun-Wook Lee, Min-Hee Ryu, Sun Kyung Baek, In Hae Park, Hee Kyung Ahn, Jae Ho Jeong, Min Hwan Kim, Dae Hyung Lee, Siheon Kim, Hyemi Moon, Serim Son, Ji-Hye Byun, Dong Sook Kim, Hyonggin An, Yeon Hee Park, Dae Young Zang
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: Electronic medical records (EMRs) have the highest value among real-world data (RWD). The aim of the present study was to propose a data collection framework of EMR-based RWD to evaluate the effectiveness and safety of cancer drugs by con
Externí odkaz:
https://doaj.org/article/62de8440afca4cdeacda3ee0a36fa0ad