Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Hye-Ran Moon"'
Autor:
Silpa Gampala, Hye-ran Moon, Randall Wireman, Jacqueline Peil, Sonia Kiran, Dana K. Mitchell, Kylee Brewster, Henry Mang, Andi Masters, Christine Bach, Whitney Smith-Kinnamen, Emma H. Doud, Ratan Rai, Amber L. Mosley, Sara K. Quinney, D. Wade Clapp, Chafiq Hamdouchi, James Wikel, Chi Zhang, Bumsoo Han, Millie M. Georgiadis, Mark R. Kelley, Melissa L. Fishel
Publikováno v:
Pharmacological Research, Vol 201, Iss , Pp 107092- (2024)
AP endonuclease-1/Redox factor-1 (APE1/Ref-1 or Ref-1) is a multifunctional protein that is overexpressed in most aggressive cancers and impacts various cancer cell signaling pathways. Ref-1′s redox activity plays a significant role in activating t
Externí odkaz:
https://doaj.org/article/aab80d4f3cdf4047a242a19cd4eadd78
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Non-contact micro-manipulation tools have enabled invasion-free studies of fragile synthetic particles and biological cells. Rapid electrokinetic patterning (REP) traps target particles/cells, suspended in an electrolyte, on an electrode sur
Externí odkaz:
https://doaj.org/article/60e1ae3613c6497eae618c989ced2693
Publikováno v:
npj Systems Biology and Applications, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Cell signaling networks are complex and often incompletely characterized, making it difficult to obtain a comprehensive picture of the mechanisms they encode. Mathematical modeling of these networks provides important clues, but the models t
Externí odkaz:
https://doaj.org/article/5b6eaeafc76c416e9397da7326bd63d1
Autor:
Cih Cheng, Naomi Deneke, Hye-ran Moon, Sae Rome Choi, Natalia Ospina-Muñoz, Bennett D. Elzey, Chelsea S. Davis, George T.-C Chiu, Bumsoo Han
Publikováno v:
Materials Today Advances, Vol 19, Iss , Pp 100408- (2023)
Recent advances in biomaterials and 3D printing/culture methods enable various tissue-engineered tumor models. However, it is still challenging to achieve native tumor-like characteristics due to lower cell density than native tissues and prolonged c
Externí odkaz:
https://doaj.org/article/fea26d9d66d24ee0b396dfe569eef5c5
Autor:
Silpa Gampala, Fenil Shah, Xiaoyu Lu, Hye-ran Moon, Olivia Babb, Nikkitha Umesh Ganesh, George Sandusky, Emily Hulsey, Lee Armstrong, Amber L. Mosely, Bumsoo Han, Mircea Ivan, Jing-Ruey Joanna Yeh, Mark R. Kelley, Chi Zhang, Melissa L. Fishel
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-24 (2021)
Abstract Background Pancreatic cancer is a complex disease with a desmoplastic stroma, extreme hypoxia, and inherent resistance to therapy. Understanding the signaling and adaptive response of such an aggressive cancer is key to making advances in th
Externí odkaz:
https://doaj.org/article/751a9e3c189b45859ea1d97745ceb7f8
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103242- (2021)
Summary: Chemotaxis is ubiquitous in many biological processes, but it still remains elusive how cells sense and decipher multiple chemical cues. In this study, we postulate a hypothesis that the chemotactic performance of cells under complex cues is
Externí odkaz:
https://doaj.org/article/e3f50d54946f482c88c8828f949d51e5
Autor:
Hye-Ran Moon, Natalia Ospina-Muñoz, Victoria Noe-Kim, Yi Yang, Bennett D Elzey, Stephen F Konieczny, Bumsoo Han
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234012 (2020)
Understanding progression of breast cancers to invasive ductal carcinoma (IDC) can significantly improve breast cancer treatments. However, it is still difficult to identify genetic signatures and the role of tumor microenvironment to distinguish pat
Externí odkaz:
https://doaj.org/article/26e92cc4368d40b8a2a0c53234f16ab3
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 4, p e1006961 (2019)
Directed cell motion in response to an external chemical gradient occurs in many biological phenomena such as wound healing, angiogenesis, and cancer metastasis. Chemotaxis is often characterized by the accuracy, persistence, and speed of cell motion
Externí odkaz:
https://doaj.org/article/e3d325da647045ae874f7dc5db7bb5be
Autor:
Olivia Babb, Fenil Shah, Lee Armstrong, Emily Hulsey, Hye-ran Moon, Amber L Mosely, Melissa L. Fishel, Jing-Ruey Joanna Yeh, Mark R. Kelley, Silpa Gampala, George E. Sandusky, Bumsoo Han, Nikkitha Umesh Ganesh, Chi Zhang, Mircea Ivan, Xiaoyu Lu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-24 (2021)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
BackgroundPancreatic cancer is a complex disease with a desmoplastic stroma, extreme hypoxia, and inherent resistance to therapy. Understanding the signaling and adaptive response of such an aggressive cancer is key to making advances in therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59882bc64608b96a6c5400722434b880
https://doaj.org/article/751a9e3c189b45859ea1d97745ceb7f8
https://doaj.org/article/751a9e3c189b45859ea1d97745ceb7f8
Cells sense various environmental cues and subsequently process intracellular signals to decide their migration direction in many physiological and pathological processes. Although several signaling molecules and networks have been identified in thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c50e81842e5152e7f69741275a6e7855
https://doi.org/10.1101/2022.04.28.489798
https://doi.org/10.1101/2022.04.28.489798
