Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Hye-Lin Ha"'
Publikováno v:
J Immunol
House dust mite (HDM) extract is a common trigger of asthma in humans. Chronic exposure to HDM also induces asthma-like pathology in mice. Allergic responses to HDM and other allergens are linked to release of IL-25, IL-33, and TSLP by epithelial cel
Publikováno v:
Oncotarget
// Hye-Lin Ha 1, 2, 5, * , Taeho Kwon 1, * , In Seon Bak 1 , Raymond L. Erikson 3 , Bo Yeon Kim 4 , Dae-Yeul Yu 1, 2 1 Disease Model Research Laboratory, Genome Editing Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)
Publikováno v:
J Invest Dermatol
IL-17 cytokines, in particular IL-17A, are critical effectors in psoriasis. Antibodies that block IL-17A are highly efficacious in treating psoriasis. Likewise, disruption of IL-17 cytokines signaling, such as via the loss of the adaptor CIKS/Act1, a
Publikováno v:
The Journal of Immunology. 195:3525-3529
Asthma is a common inflammatory disease of airways that is often associated with type 2 responses triggered by allergens, such as house dust mites (HDMs). IL-25 is a key mucosal cytokine that may be produced by stressed epithelial cells; it rapidly a
Autor:
Hongshan Wang, Alan Sher, Ulrich Siebenlist, Ilaria Tassi, Wanhu Tang, Dragana Jankovic, Sun Saret, Hye-Lin Ha, Estefania Claudio
Publikováno v:
European Journal of Immunology. 45:1972-1979
The atypical IκB family member Bcl-3 associates with p50/NF-κB1 or p52/NF-κB2 homodimers in nuclei, thereby either positively or negatively modulating transcription in a context-dependent manner. Previously we reported that Bcl-3 was critical for
Autor:
Wanhu Tang, Estefania Claudio, Sun Saret, Nimisha Rikhi, Ulrich Siebenlist, Daniel H. Kaplan, Hongshan Wang, Hye lin Ha, Ilaria Tassi
Publikováno v:
European Journal of Immunology. 45:1059-1068
Bcl-3 is an atypical member of the IκB family. Bcl-3 functions as a cofactor of p50/NF-κB1 or p52/NF-κB2 homodimers in nuclei, where it modulates NF-κB-regulated transcription in a context-dependent way. Bcl-3 has tumorigenic potential, is critic
Publikováno v:
Annals of Gastroenterology & Hepatology. 2011, Vol. 9 Issue 96, p6035-6043. 9p.
Autor:
Gabor G. Illei, Tanya N. Mayadas, Ulrich Siebenlist, Estefania Claudio, Hua Zhou, Caitlyn C. Tivy, Prapaporn Pisitkun, Hye-Lin Ha, Hongshan Wang
Publikováno v:
Immunity. 37:1104-1115
SummarySystemic lupus erythematosus is a potentially fatal autoimmune disease. Although interleukin-17 (IL-17) has been linked to human lupus and mouse models of this disease, it has not been addressed whether this cytokine plays a critical role in f
Autor:
Jin Man Kim, Tae-Hoon Lee, Ying-Hao Han, Sun-Uk Kim, Eun-Kyeong Jo, Bo Yeon Kim, Dae-Yeul Yu, Taeho Kwon, Do Young Yoon, Hye-Lin Ha
Publikováno v:
BMB REPORTS(45): 10
The role of peroxiredoxin (Prx) I as an erythrocyte antioxidant defense in red blood cells (RBCs) is controversial. Here we investigated the function of Prx I by using Prx I-/- and Prx I/II-/- mice. Prx I-/- mice exhibited a normal blood profile. How
Autor:
Doo-Sang Park, Taeho Kwon, Ying-Hao Han, Sang Yeol Lee, Eui-Jeon Woo, Sue Goo Rhee, Dae-Yeul Yu, Eitan Fibach, Jin-Man Kim, Sun-Uk Kim, Do Young Yoon, Bo Yeon Kim, Sang-Hee Lee, Ho-Byoung Chae, Hye-Lin Ha, Dong-Seok Lee
Publikováno v:
Biochemical and Biophysical Research Communications. 426:427-432
The pathophysiology of oxidative hemolytic anemia is closely associated with hemoglobin (Hb) stability; however, the mechanism of how Hb maintains its stability under oxidative stress conditions of red blood cells (RBCs) carrying high levels of oxyge