Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Hye-Guk Ryu"'
Autor:
Saebom Lee, Hye Guk Ryu, Sin Ho Kweon, Hyerynn Kim, Hyeonwoo Park, Kyung-Ha Lee, Sang-Min Jang, Chan Hyun Na, Sangjune Kim, Han Seok Ko
Publikováno v:
Cells, Vol 11, Iss 24, p 3972 (2022)
Non-receptor tyrosine kinase, c-Abl plays a role in the pathogenesis of several neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease. Here, we found that TDP-43, which was one of the main proteins comprising pathologica
Externí odkaz:
https://doaj.org/article/52a7d62560b54061891c5a0f3f91c34e
Autor:
Hoe-Yune Jung, Dongyeop Lee, Hye Guk Ryu, Bo-Hwa Choi, Younghoon Go, Namgyu Lee, Dohyun Lee, Heehwa G. Son, Jongsu Jeon, Seong-Hoon Kim, Jong Hyuk Yoon, Seon-Min Park, Seung-Jae V. Lee, In-Kyu Lee, Kwan Yong Choi, Sung Ho Ryu, Kazunari Nohara, Seung-Hee Yoo, Zheng Chen, Kyong-Tai Kim
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Robust mitochondrial respiration provides energy to support physical performance and physiological well-being, whereas mitochondrial malfunction is associated with various pathologies and reduced longevity. In the current study, we tested wh
Externí odkaz:
https://doaj.org/article/10201d00788242438ead92d92999e6dd
Autor:
Namgyu Lee, Hye Guk Ryu, Jung-Hee Kwon, Dae-Kyum Kim, Sae Rom Kim, Hee Jung Wang, Kyong-Tai Kim, Kwan Yong Choi
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165835 (2016)
The role of Sirtuin 6 (SIRT6) as a tumor suppressor or oncogene in liver cancer remains controversial. Thus, we identified the specific role of SIRT6 in the progression of hepatocellular carcinoma (HCC). SIRT6 expression was significantly higher in H
Externí odkaz:
https://doaj.org/article/a340a91331c641588bf59444fa79f74d
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 2, Iss 1, Pp 1-9 (2012)
Background and Purpose: The relationship between apolipoprotein E (ApoE) and onset of vascular dementia remains controversial. The aim of this study was to evaluate the relationship between ApoE polymorphism and the onset of subcortical vascular deme
Externí odkaz:
https://doaj.org/article/a1596a1971cb4e26a97157bde77ea654
Autor:
Sung Key Jang, Kyong-Tai Kim, Kyung-Ha Lee, Hee Yi, Hye Guk Ryu, Sung Wook Kim, Hyun-Ok Ku, Youngseob Jung, Sohyun Gu
Publikováno v:
J Biol Chem
Most living creatures have a circadian rhythm that is generated by a precisely regulated transcriptional–translational feedback loop of clock genes. Brain and muscle ARNT-like 1 (BMAL1) is one of the core clock genes and transcription factors that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a8844a7cc9437ac851c1c8468cf93c3
https://doi.org/10.1074/jbc.ra118.006947
https://doi.org/10.1074/jbc.ra118.006947
Betulinic acid inhibits high-fat diet-induced obesity and improves energy balance by activating AMPK
Autor:
Sung Hyun Yang, K.-D. Kim, Hoe-Yune Jung, Jong-Seong Jeon, J.-B. Kim, C.-K. Hyun, Hye Guk Ryu, C.H. Park, B.-H. Choi, H.Y. Yoo, Bobae Kim, Kyong-Tai Kim, S. Fang
Publikováno v:
Nutrition, Metabolism and Cardiovascular Diseases. 29:409-420
Background and aim Metabolic syndromes are prevalent worldwide and result in various complications including obesity, cardiovascular disease and type II diabetes. Betulinic acid (BA) is a naturally occurring triterpenoid that has anti-inflammatory pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4859360dd5b21ca06b60862953abe7f
https://doi.org/10.1016/j.numecd.2018.12.001
https://doi.org/10.1016/j.numecd.2018.12.001
Publikováno v:
Journal of Neurochemistry. 149:413-426
Misfolded proteins with abnormal polyglutamine (polyQ) expansion cause neurodegenerative disorders, including Huntington's disease. Recently, it was found that polyQ aggregates accumulate as a result of vaccinia-related kinase 2 (VRK2)-mediated degra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aadf1bed980f4a169509a81f9dc46af7
https://doi.org/10.1111/jnc.14638
https://doi.org/10.1111/jnc.14638
Autor:
Hye Guk, Ryu, Youngseob, Jung, Namgyu, Lee, Ji-Young, Seo, Sung Wook, Kim, Kyung-Ha, Lee, Do-Yeon, Kim, Kyong-Tai, Kim
Publikováno v:
International Journal of Molecular Sciences
THeterogeneous nuclear ribonucleoprotein (HNRNP) A1 is the most abundant and ubiquitously expressed member of the HNRNP protein family. In recent years, it has become more evident that HNRNP A1 contributes to the development of neurodegenerative dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::61f4c3c89b59e78de02275e1331c2ed1
https://pubmed.ncbi.nlm.nih.gov/34071140
https://pubmed.ncbi.nlm.nih.gov/34071140
Parkinson’s disease (PD) is the second most common neurodegenerative disorder. Low education is known to be a risk factor for Alzheimer’s disease (AD). Since many patients with PD show pathological findings similar to AD in addition to Lewy body,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dccdd6472ee62d723e7ede7811a0e405
Publikováno v:
Science Advances
Noncanonical translation of the glutamate receptor is stimulated by nerve signal–mediated up-regulation of an RNA binding protein.
The AMPA receptor subunit GluA1 is essential for induction of synaptic plasticity. While various regulatory mech
The AMPA receptor subunit GluA1 is essential for induction of synaptic plasticity. While various regulatory mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da598308aa7494ee80f7c29ae746f142
http://europepmc.org/articles/PMC7679154
http://europepmc.org/articles/PMC7679154