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Protective effects of extracorporeal shockwave on rat chondrocytes and temporomandibular joint osteoarthritis; preclinical evaluation with in vivo 99mTc-HDP SPECT and ex vivo micro-CT

Autor: Bom Sahn Kim, Younghwa Kim, Ji-In Bang, Hai-Jeon Yoon, Soo Jeong Han, Hye-Jin Son, JiHoi Kim, Hasuk Bae, Yemi Kim

Publikováno v: Osteoarthritis and Cartilage. 27:1692-1701

Summary Objective Extracorporeal shockwave therapy (ESWT) has been shown to have chondroprotective effects on arthritic diseases. We investigated the effects of ESWT on temporomandibular joint osteoarthritis (TMJOA) using rat chondrocytes and TMJOA r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::811fb399a641930b442727c7ed1545a1
https://doi.org/10.1016/j.joca.2019.07.008

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Abstract 1216: New therapeutic antibody ('WM-A1') for treatment of low or no PD-L1 NSCLC patients

Autor: Hyun Ho Lee, Jai-Hee Moon, Ha Na Kim, Dong-Hoon Jin, Mi So Lee, Joonyee Jeong, Seung-Woo Hong, Seunggeon Bae, Hye jin Son, Wonhwa Shin, Daeun Kim, Chun-Ho Park, Joseph Kim, Seongrak Kim, Lee Min-Ki

Publikováno v: Cancer Research. 81:1216-1216

The number of lung cancer patients is increasing every year worldwide. For these patients' treatment, not only anticancer drugs but also immune anticancer drugs are rapidly being developed. So far, the PD-1 antibody is widely used in treating NSCLC p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b959b6b6bf0bed611993f483fe9cbc5
https://doi.org/10.1158/1538-7445.am2021-1216

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Oncostatin M Suppresses Activation of IL-17/Th17 via SOCS3 Regulation in CD4+ T Cells

Autor: Seung Hoon Lee, Hyeon-Beom Seo, Seon-Yeong Lee, Mi-La Cho, Sung-Hwan Park, Eun-Ji Yang, Jae-Kyung Kim, Eun-Kyung Kim, Hye-Jin Son

Publikováno v: The Journal of Immunology. 198:1484-1491

Oncostatin M (OSM) is a pleiotropic cytokine and a member of the IL-6 family. It has both proinflammatory and anti-inflammatory functions and is involved in the activation of STAT3 and STAT5. Rheumatoid arthritis is an autoimmune disease that causes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c2106884d4bfd2217fe4a206d2a416
https://doi.org/10.4049/jimmunol.1502314

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Metformin attenuates graft-versus-host disease via restricting mammalian target of rapamycin/signal transducer and activator of transcription 3 and promoting adenosine monophosphate–activated protein kinase-autophagy for the balance between T helper 17 and Tregs

Autor: Su-Jin Moon, Sung-Hee Lee, Min-Jung Park, Eun-Kyung Kim, Jae-Kyeong Byun, Mi-La Cho, Sung-Hwan Park, Hye-Jin Son, Dong Yun Shin, Seon-Yeong Lee, Chul-Woo Yang

Publikováno v: Translational Research. 173:115-130

Acute graft-versus-host disease (aGVHD), caused by donor T cell-mediated injury to host tissues, is a problem in allogeneic bone marrow transplantation. The transition from naïve to effector T cells is accompanied by shift in metabolism main pathway

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5275b93b3a858b4006ff16251eba15
https://doi.org/10.1016/j.trsl.2016.03.006

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Artificial intelligence for the prediction of tensile properties by using microstructural parameters in high strength steels

Autor: Moobum Kim, Seung Ki Moon, Min Sik Lee, Da Seul Shin, Seong Jin Park, Doohee Kim, N.S. Reddy, Kyung Tae Kim, Hye Jin Son, Hyokyung Sung, Sangshik Kim, Jungsub Lee, Im Doo Jung, Ji-Hun Yu

Publikováno v: Materialia. 11:100699

Artificial intelligence is widely employed in metallurgy for its ability to solve complex phenomena, which are associated with the learning process of previously obtained experimental data. Although numerous physical modeling techniques have been imp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b557761fe40f4bdf315eb27175c07c
https://doi.org/10.1016/j.mtla.2020.100699

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Embedding sensors using selective laser melting for self-cognitive metal parts

Autor: Hyokyung Sung, Seok Woo Lee, Jungsub Lee, Jungho Choe, Moobum Kim, Ki-bong Kim, Sangsun Yang, Im Doo Jung, Min Sik Lee, Jaecheol Yun, Hye Jin Son, Ji-Hun Yu, Kyung Tae Kim, Seung Ki Moon

Publikováno v: Additive Manufacturing. 33:101151

We devised a novel method to embed sensors or integrated circuit (IC) chips into metal components by using a selective laser melting (SLM) process. The concept of a protective layer is introduced to fabricate all parts without damaging the sensors du

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df0d6c690189333c3def3ac53243b000
https://doi.org/10.1016/j.addma.2020.101151

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