Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Hye Yeon Choi"'
Autor:
Hye Yeon Choi, Yicheng Zhu, Xuyao Zhao, Simran Mehta, Juan Carlos Hernandez, Jae-Jin Lee, Yi Kou, Risa Machida, Mauro Giacca, Giannino Del Sal, Ratna Ray, Hyungjin Eoh, Stanley M. Tahara, Lin Chen, Hidekazu Tsukamoto, Keigo Machida
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 2, Pp 461-477 (2024)
Abstract The P53-destabilizing TBC1D15-NOTCH protein interaction promotes self-renewal of tumor-initiating stem-like cells (TICs); however, the mechanisms governing the regulation of this pathway have not been fully elucidated. Here, we show that TBC
Externí odkaz:
https://doaj.org/article/cce91a31632d430a830e45249520ef25
Autor:
Hye Yeon Choi, Yicheng Zhu, Xuyao Zhao, Simran Mehta, Juan Carlos Hernandez, Jae-Jin Lee, Yi Kou, Risa Machida, Mauro Giacca, Giannino Del Sal, Ratna Ray, Hyungjin Eoh, Stanley M. Tahara, Lin Chen, Hidekazu Tsukamoto, Keigo Machida
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 10, Pp 2323-2323 (2024)
Externí odkaz:
https://doaj.org/article/15ad0b71720f4c6c94a3eda7ed45a7d3
Autor:
Sonal Sinha, Satoka Aizawa, Yasuhiro Nakano, Alexander Rialdi, Hye Yeon Choi, Rajan Shrestha, Stephanie Q. Pan, Yibu Chen, Meng Li, Audrey Kapelanski-Lamoureux, Gregory Yochum, Linda Sher, Satdarshan Paul Monga, Anthoula Lazaris, Keigo Machida, Michael Karin, Ernesto Guccione, Hidekazu Tsukamoto
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Hepatocellular carcinoma (HCC) is the 3rd most deadly malignancy. Activated hepatic stellate cells (aHSC) give rise to cancer-associated fibroblasts in HCC and are considered a potential therapeutic target. Here we report that selective abla
Externí odkaz:
https://doaj.org/article/6713daa54c2940a6b1e1813574aeb767
Autor:
Da-Wei Yeh, Xuyao Zhao, Hifzur R. Siddique, Mengmei Zheng, Hye Yeon Choi, Tatsuya Machida, Padmini Narayanan, Yi Kou, Vasu Punj, Stanley M. Tahara, Douglas E. Feldman, Lin Chen, Keigo Machida
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract RNA-binding protein Musashi 2 (MSI2) is elevated in several cancers and is linked to poor prognosis. Here, we tested if MSI2 promotes MYC and viral mRNA translation to induce self-renewal via an internal ribosome entry sequence (IRES). We pe
Externí odkaz:
https://doaj.org/article/f53b059996d14f06981134f03c1b966e
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Downregulation of human leukocyte antigen (HLA) class I is one mechanism of escaping anti-tumor immunity by tumor cells. This study was conducted to compare HLA class I expression in ductal carcinoma in situ (DCIS) and invasive breast carcin
Externí odkaz:
https://doaj.org/article/1ebc1a5be08b44028b49bc2ad021eac1
Autor:
Juan Carlos Hernandez, Da‐Wei Yeh, Joel Marh, Hye Yeon Choi, Julia Kim, Shefali Chopra, Li Ding, Matthew Thornton, Brendan Grubbs, Leonard Makowka, Linda Sher, Keigo Machida
Publikováno v:
Hepatology Communications, Vol 6, Iss 7, Pp 1549-1560 (2022)
Abstract The ability of the liver to regenerate after injury makes it an ideal organ to study for potential therapeutic interventions. Mesenchymal stem cells (MSCs) possess self‐renewal and differentiation properties, as well as anti‐inflammatory
Externí odkaz:
https://doaj.org/article/922690c010f1446d8f5cb8b8763f520c
Autor:
Soo Yeun Sim, Hye Yeon Choi, Min Ho Jung, Soo Young Lee, Jung Woo Rhim, Hyun Mi Kang, Dae Chul Jeong
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 20, Iss 1, Pp 1-7 (2022)
Abstract Background In women with autoimmune rheumatic disorders (ARD), pregnancy complications or postpartum events are more frequent compared to the general population. Transplacental autoantibodies or cytokines influence various fetal and neonatal
Externí odkaz:
https://doaj.org/article/8f050cb19a304235a34a76f3fcb0c1d1
Autor:
Soo Yeun Sim, Hye Yeon Choi, Seung Bum Han, Nack Gyun Chung, Bin Cho, MyungShin Kim, Dae Chul Jeong
Publikováno v:
Clinical Pediatric Hematology-Oncology, Vol 28, Iss 2, Pp 84-88 (2021)
X-linked inhibitor of apoptosis protein (XIAP) deficiency is a rare immunodeficiency disorder. A 13-month-old boy was diagnosed with pure red cell aplasia (PRCA) and treated with steroid and cyclosporine. Bone marrow showed diminished erythroid precu
Externí odkaz:
https://doaj.org/article/13fb3f7bc74a4647b07143f75d703685
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Tumor immune microenvironment plays a crucial role in tumor progression. We performed immune profiling to compare immune-related gene expression between ductal carcinoma in situ (DCIS) and invasive carcinoma of the breast using nCounter PanC
Externí odkaz:
https://doaj.org/article/7a35859373714fccb865d1efbe04a89e
Autor:
Hye Yeon Choi, Juyoung Lee, Danbi Kim, Jin-Soon Suh, Joong Hyun Bin, Soo Young Lee, Kyoung Soon Cho
Publikováno v:
Neonatal Medicine, Vol 27, Iss 4, Pp 181-186 (2020)
Being born small for gestational age (SGA) has been strongly associated with mortality during the perinatal period and long-term risk of metabolic syndrome, including type 2 diabetes mellitus, hypertension, hyperlipidemia, and coronary heart disease.
Externí odkaz:
https://doaj.org/article/ff41b8ec392e453fa7c1c30547875930