Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Hye Jung Ihn"'
Autor:
Soomin Lim, Hye Jung Ihn, Ju Ang Kim, Jong-Sup Bae, Jung-Eun Kim, Yong Chul Bae, Hong-In Shin, Tae Hoon Kim, Eui Kyun Park
Publikováno v:
Animal Cells and Systems, Vol 27, Iss 1, Pp 1-9 (2023)
ABSTRACTRegulation of osteoclastogenesis and bone-resorbing activity can be an efficacious strategy for treating bone loss diseases because excessive osteoclastic bone resorption leads to the development of such diseases. Here, we investigated the ro
Externí odkaz:
https://doaj.org/article/73e8002c53b94daeba4611bf573c41ba
Autor:
Hye Jung Ihn, Jiwon Lim, Kiryeong Kim, Sang-Hyeon Nam, Soomin Lim, Su Jeong Lee, Jong-Sup Bae, Tae Hoon Kim, Jung-Eun Kim, Moon-Chang Baek, Yong Chul Bae, Eui Kyun Park
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8299 (2021)
Postmenopausal osteoporosis is closely associated with excessive osteoclast formation and function, resulting in the loss of bone mass. Osteoclast-targeting agents have been developed to manage this disease. We examined the effects of ciclopirox on o
Externí odkaz:
https://doaj.org/article/50573e0a9105437e8107329af4815d09
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 6129 (2021)
Megakaryocytes (MKs) differentiate from hematopoietic stem cells and produce platelets at the final stage of differentiation. MKs directly interact with bone cells during bone remodeling. However, whether MKs are involved in regulating bone metabolis
Externí odkaz:
https://doaj.org/article/afb9938666414b2ea773734fbce16f43
Autor:
Hye Jung Ihn, Taeho Lee, Doohyun Lee, Jong-Sup Bae, Sang-Hyun Kim, Il Ho Jang, Yong Chul Bae, Hong-In Shin, Eui Kyun Park
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Excessive osteoclastic activity results in pathological bone resorptive diseases, such as osteoporosis, periodontitis, and rheumatoid arthritis. As imidazole-containing compounds possess extensive therapeutic potential for the management of diverse d
Externí odkaz:
https://doaj.org/article/b6f886b0fb914a7a99aa2d6cb6d2c033
Autor:
Hye Jung Ihn, Taeho Lee, Ju Ang Kim, Doohyun Lee, Nam Doo Kim, Hong-In Shin, Yong Chul Bae, Eui Kyun Park
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170159 (2017)
An abnormal increase in osteoclast differentiation and activation results in various bone-resorptive diseases, including periodontitis, rheumatoid arthritis, and osteoporosis. Chemical compounds containing pyrimidine ring have been shown to regulate
Externí odkaz:
https://doaj.org/article/1421b674b1f344f38984c72a4efc6bac
Autor:
Hye Jung Ihn, Ju Ang Kim, Soomin Lim, Sang-Hyeon Nam, So Hyeon Hwang, Jiwon Lim, Gi-Young Kim, Yung Hyun Choi, You-Jin Jeon, Bae-Jin Lee, Jong-Sup Bae, Yeo Hyang Kim, Eui Kyun Park
Publikováno v:
Nutrients, Vol 11, Iss 6, p 1392 (2019)
There is growing interest in bioactive substances from marine organisms for their potential use against diverse human diseases. Osteoporosis is a skeletal disorder associated with bone loss primarily occurring through enhanced osteoclast differentiat
Externí odkaz:
https://doaj.org/article/575931f1d8044ead9c4267d2cafd2012
Autor:
Kiryeong Kim, Tae Hoon Kim, Hye Jung Ihn, Jung Eun Kim, Je-Yong Choi, Hong-In Shin, Eui Kyun Park
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 2, p 601 (2018)
Purpurogallin, a benzotropolone-containing natural compound, has been reported to exhibit numerous biological and pharmacological functions, such as antioxidant, anticancer, and anti-inflammatory effects. In this study, we enzymatically synthesized p
Externí odkaz:
https://doaj.org/article/ad215391a05d483ba020714c66959fd5
Autor:
Hye Jung Ihn, Ju Ang Kim, Hye Sung Cho, Hong-In Shin, Gi-Young Kim, Yung Hyun Choi, You-Jin Jeon, Eui Kyun Park
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 12, p 2635 (2017)
Marine algae possess a variety of beneficial effects on human health. In this study, we investigated whether diphlorethohydroxycarmalol (DPHC), isolated from Ishige okamurae, a brown alga, suppresses receptor activator of nuclear factor-κB ligand (R
Externí odkaz:
https://doaj.org/article/81f124f6cbb940a3860d5cfdc6bef013
Autor:
Hye Jung Ihn, Doohyun Lee, Taeho Lee, Sang-Hyun Kim, Hong-In Shin, Yong Chul Bae, Jung Min Hong, Eui Kyun Park
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142201 (2015)
Abnormally elevated formation and activation of osteoclasts are primary causes for a majority of skeletal diseases. In this study, we found that KP-A159, a newly synthesized thiazolopyridine derivative, inhibited osteoclast differentiation and functi
Externí odkaz:
https://doaj.org/article/7fa9e11aac7a4698bbb8d5ab888ece7b
Autor:
Freshet Assefa, Eui Kyun Park, Hye Jung Ihn, Jiwon Lim, Ju-Ang Kim, Soo-min Lim, Sang-Hyeon Nam, Yong Chul Bae
Publikováno v:
Tissue Eng Regen Med
BACKGROUND: This study investigates the effects of a neuropeptide, secretoneurin (SN), on bone regeneration in an experimental mouse model. METHODS: The effects of SN on cell proliferation, osteoblast marker genes expression, and mineralization were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dcf5fa4b22f56e40294c3ed23b834e9
https://doi.org/10.1007/s13770-020-00304-1
https://doi.org/10.1007/s13770-020-00304-1