Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Hye Joung Cho"'
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Akademický článek
Etomoxir, a carnitine palmitoyltransferase 1 inhibitor, combined with temozolomide reduces stemness and invasiveness in patient-derived glioblastoma tumorspheres
Autor: Jin-Kyoung Shim, Seonah Choi, Seon-Jin Yoon, Ran Joo Choi, Junseong Park, Eun Hee Lee, Hye Joung Cho, Suji Lee, Wan-Yee Teo, Ju Hyung Moon, Hyun Sil Kim, Eui Hyun Kim, Jae-Ho Cheong, Jong Hee Chang, Jong In Yook, Seok-Gu Kang
Publikováno v: Cancer Cell International, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Introduction The importance of fatty acid oxidation (FAO) in the bioenergetics of glioblastoma (GBM) is being realized. Etomoxir (ETO), a carnitine palmitoyltransferase 1 (CPT1) inhibitor exerts cytotoxic effects in GBM, which involve interr
Externí odkaz: https://doaj.org/article/81126cca355a41108090049fa85eea74
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2
Akademický článek
Combinatorial Therapeutic Effect of Inhibitors of Aldehyde Dehydrogenase and Mitochondrial Complex I, and the Chemotherapeutic Drug, Temozolomide against Glioblastoma Tumorspheres
Autor: Hun Ho Park, Junseong Park, Hye Joung Cho, Jin-Kyoung Shim, Ju Hyung Moon, Eui Hyun Kim, Jong Hee Chang, Soo Youl Kim, Seok-Gu Kang
Publikováno v: Molecules, Vol 26, Iss 2, p 282 (2021)
Resident cancer cells with stem cell-like features induce drug tolerance, facilitating survival of glioblastoma (GBM). We previously showed that strategies targeting tumor bioenergetics present a novel emerging avenue for treatment of GBM. The object
Externí odkaz: https://doaj.org/article/59c63ac610934e12b72bb3de75bc0834
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3
Dual inhibition of CPT1A and G6PD suppresses glioblastoma tumorspheres
Autor: Seo Jin Kim, Soo Jeong Park, Junseong Park, Hye Joung Cho, Jin-Kyoung Shim, Jieun Seon, Ran Joo Choi, Seon-Jin Yoon, Ju Hyung Moon, Eui Hyun Kim, Eui Kyo Seo, Sun Ho Kim, Hyun Sil Kim, Wan-Yee Teo, Jong Hee Chang, Jong In Yook, Seok-Gu Kang
Publikováno v: Journal of neuro-oncology. 160(3)
Limited treatment options are currently available for glioblastoma (GBM), an extremely lethal type of brain cancer. For a variety of tumor types, bioenergetic deprivation through inhibition of cancer-specific metabolic pathways has proven to be an ef
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542e90e2f573a111805a5e276f2b95e9
https://pubmed.ncbi.nlm.nih.gov/36396930
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