Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Hye Joa Oh"'
Autor:
Jin-Sil Park, Mi-Kyung Park, Hye-Joa Oh, Yun-Ju Woo, Mi-Ae Lim, Jong-Ho Lee, Ji Hyeon Ju, Young Ok Jung, Zang Hee Lee, Sung-Hwan Park, Ho-Youn Kim, Mi-La Cho, Jun-Ki Min
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51377 (2012)
Chronic autoimmune inflammation, which is commonly observed in rheumatoid arthritis (RA), disrupts the delicate balance between bone resorption and formation causing thedestruction of the bone and joints. We undertook this study to verify the effects
Externí odkaz:
https://doaj.org/article/137f44bb68954b9a96217a8d52978b11
Autor:
Sun-Hee Hwang, Mi-La Cho, Ho-Youn Kim, Jin-Sil Park, Young Woo Park, Sung-Hwan Park, Mi-Ae Lim, Yoon Sunha, Seok-Ho Yoo, Jun-Geol Ryu, Bum-Chan Park, Hye-Joa Oh, SeungCheon Yang, KyungAh Jung
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(1)
This study was aimed at investigating the therapeutic effects of BITRAP, a bispecific fusion protein targeting TNF-α and IL-21, on the development of autoimmune arthritis in humans and mice. To verify the effects of BITRAP in human, peripheral blood
Autor:
Ho-Youn Kim, Eun-Kyung Kim, Jun-Geol Ryu, Sung-Hwan Park, Ji Hyeon Ju, Seung-Ki Kwok, Jin-Sil Park, Mi-La Cho, Mi-Ae Lim, Hye-Joa Oh, Sung-Min Kim
Publikováno v:
Arthritis & Rheumatology. 66:918-929
Objective To investigate the impact of STA-21, a promising STAT-3 inhibitor, on the development and progression of inflammatory arthritis and to determine the possible mechanisms by which STA-21 has antiarthritic effects in interleukin-1 receptor ant
Autor:
Joo-Yeon Jhun, Sung-Hwan Park, Jin-Sil Park, Seung-Ki Kwok, Mi-La Cho, Young-Gyu Cho, Ji Hyeon Ju, Mi-Ae Lim, Ho-Youn Kim, Eun-Kyung Kim, Hye-Joa Oh, Young Woo Park, Kyung-Su Park
Publikováno v:
The American Journal of Pathology. 183:857-867
Bone destruction is critical in the functional disability of patients with rheumatoid arthritis (RA). Osteoclasts, specialized bone-resorbing cells regulated by cytokines, such as receptor activator of NF-κB ligand (RANKL), are primarily implicated
Autor:
Chang-Min Kang, Mi-La Cho, Ji Hyeon Ju, Seung-Ki Kwok, Kyung Su Park, Young Ok Jung, Young-Chul Sung, Hye-Joa Oh, Sung-Hwan Park, Seong Jeong Park, Jin-Sil Park, Ho-Youn Kim, Yu-Jung Heo
Publikováno v:
Immunology. 137:326-335
Interleukin (IL)-27 is a heterodimeric cytokine that is known to have both stimulatory and inhibitory functions during immune responses. We investigated the effects of IL-27 on arthritis and bone erosion in the murine collagen-induced arthritis (CIA)
Autor:
Mi-La Cho, Byung Ha Chung, In O Sun, Shang Guo Piao, Yeong J. Choi, Hoon Suk Park, Yong-Soo Kim, Hyeon Seok Hwang, Bum Soon Choi, Cheol Whee Park, Sun R. Choi, Chul Woo Yang, Hye Joa Oh
Publikováno v:
Immunology. 136:344-351
The aim of this study is to investigate the clinical significance of the ratio between interleukin-17 (IL-17) secreting cell and FOXP3-positive regulatory T cell (FOXP3+ Treg) infiltration in renal allograft tissues with acute T-cell-mediated rejecti
Autor:
Ji Hyeon Ju, Yang Mi Her, Hye Joa Oh, Mi La Cho, Kyung Su Park, Seung Ki Kwok, Do Sik Min, Eun Mi Park, Mi Kyung Park, Sung Hwan Park, Ho-Youn Kim
Publikováno v:
Immunology Letters. 139:42-51
Osteoclastogenesis plays an important role in joint destruction in rheumatoid arthritis (RA). IL-15 is a pleiotropic proinflammatory cytokine that appears to help mediate the pathological bone loss. This study was undertaken to explore the signaling
Autor:
Hye Joa Oh, Mi La Cho, Byung Ha Chung, Min-Jung Park, Seok-Goo Cho, Jong Wook Lee, So Youn Min, Ho-Youn Kim, Young Gue Cho, Hyun Sil Park
Publikováno v:
Arthritis & Rheumatism. 63:1668-1680
Objective Bone marrow–derived mesenchymal stem cells (MSCs) can prevent various autoimmune diseases. We examined the therapeutic potential of transforming growth factor β (TGFβ)–transduced MSCs in experimental autoimmune arthritis, using an acc
Autor:
Doo-Jin Paik, Jeehee Youn, Mi-La Cho, Sang Mee Kang, Wang Sik Cho, Hye-Joa Oh, Hyun-Joo Park, Eunkyeong Jang
Publikováno v:
The Journal of Immunology. 186:1546-1553
Foxp3+ regulatory T cells (Tregs) are crucial for maintaining T cell tolerance, but their role in humoral autoimmunity remains unclear. To address this, we combined a model of autoantibody-dependent arthritis (K/BxN) with Foxp3 mutant scurfy mice to
Autor:
Hyun Sil Park, Kyung Ho Ha, So Youn Min, Min-Jung Park, Jin Choi, Ho-Youn Kim, Hye Joa Oh, Dae Myung Jue, Ji Hyeon Ju, Mi Sun Byun
Publikováno v:
European Journal of Pharmacology. 595:108-113
N-tosyl-l-phenylalanine chloromethyl ketone (TPCK) is known to inhibit NF-kappaB activation and the expression of inflammation mediators in cultured cells. We measured the potential of TPCK to inhibit the pathogenesis of collagen-induced arthritis by