Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Hye Hyun Ahn"'
Autor:
Hye-Hyun Ahn, Christine Carrington, Yizong Hu, Heng-wen Liu, Christy Ng, Hwanhee Nam, Andrew Park, Catherine Stace, Will West, Hai-Quan Mao, Martin G. Pomper, Christopher G. Ullman, Il Minn
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Treatment of cancers in the lung remains a critical challenge in the clinic for which gene therapy could offer valuable options. We describe an effective approach through systemic injection of engineered polymer/DNA nanoparticles that mediat
Externí odkaz:
https://doaj.org/article/028da9e9162b445aa5e23cd58b3acf81
Autor:
Srikanth Boinapally, Hye-Hyun Ahn, Bei Cheng, Mary Brummet, Hwanhee Nam, Kathleen L. Gabrielson, Sangeeta R. Banerjee, Il Minn, Martin G. Pomper
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Prostate-specific membrane antigen (PSMA) is a promising target for the treatment of advanced prostate cancer (PC) and various solid tumors. Although PSMA-targeted radiopharmaceutical therapy (RPT) has enabled significant imaging and prostat
Externí odkaz:
https://doaj.org/article/66509369cb3640a3b49a1ee996b47027
Autor:
Emmanuel Datan, Il Minn, Peng Xu, Qing-Li He, Hye-Hyun Ahn, Biao Yu, Martin G. Pomper, Jun O. Liu
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101536- (2020)
Summary: A major hurdle in the treatment of cancer is chemoresistance induced under hypoxia that is characteristic of tumor microenvironment. Triptolide, a potent inhibitor of eukaryotic transcription, possesses potent antitumor activity. However, it
Externí odkaz:
https://doaj.org/article/33df17c77b184861b71368215af366fc
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 373 (2022)
The inherent instability of nucleic acids within serum and the tumor microenvironment necessitates a suitable vehicle for non-viral gene delivery to malignant lesions. A specificity-conferring mechanism is also often needed to mitigate off-target tox
Externí odkaz:
https://doaj.org/article/5b3f1e186ead44b4bce17988f03ed13d
Autor:
Andrew Park, Hwanhee Nam, Hye Hyun Ahn, Will West, Catherine Stace, Christopher G. Ullman, Yizong Hu, Martin G. Pomper, Il Minn, Christy Ng, Hai-Quan Mao, Christine V.F. Carrington, Heng Wen Liu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Treatment of cancers in the lung remains a critical challenge in the clinic for which gene therapy could offer valuable options. We describe an effective approach through systemic injection of engineered polymer/DNA nanoparticles that mediate tumor-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea7ce53cb53379ab1d49ffc42dbbc59e
https://doaj.org/article/028da9e9162b445aa5e23cd58b3acf81
https://doaj.org/article/028da9e9162b445aa5e23cd58b3acf81
Autor:
Hwanhee Nam, Il Minn, Mary Brummet, Martin G. Pomper, Kathleen L. Gabrielson, Srikanth Boinapally, Bei Cheng, Hye Hyun Ahn, Sangeeta Ray Banerjee
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Prostate-specific membrane antigen (PSMA) is a promising target for the treatment of advanced prostate cancer (PC) and various solid tumors. Although PSMA-targeted radiopharmaceutical therapy (RPT) has enabled significant imaging and prostate-specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22908e9035dfcd244c4d321124873ccc
https://doaj.org/article/66509369cb3640a3b49a1ee996b47027
https://doaj.org/article/66509369cb3640a3b49a1ee996b47027
Autor:
Kuntao Chen, Caleb F. Anderson, Jung Hee Seo, Hai-Quan Mao, Rajat Mittal, Martin G. Pomper, Il Minn, Hye Hyun Ahn, Yizong Hu, Zhiyu He, Like Gong, Xiyu Ke, Marion Pang, Yue Hao, Gregory P. Howard, Heng Wen Liu, Christine A. Carrington, Mary Brummet, Christopher G. Ullman, Honggang Cui, Jinchang Zhu
Publikováno v:
ACS Nano
Polyelectrolyte complex (PEC) nanoparticles assembled from plasmid DNA (pDNA) and polycations such as linear polyethyleneimine (lPEI) represent a major non-viral delivery vehicle for gene therapy tested thus far. Efforts to control the size, shape an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f949cc0899c2bea264522f52ea49e1d
https://doi.org/10.1021/acsnano.9b03334
https://doi.org/10.1021/acsnano.9b03334
Autor:
Mikhail V. Pletnikov, Heather Valentine, Hwanhee Nam, Olga Pletnikova, Il Minn, Ravi Naik, William B. Mathews, Yunkou Wu, Yong Du, Varia Misheneva, Yuchuan Wang, Matthew D. Smith, Peter A. Calabresi, Wojciech G. Lesniak, Andrew Hall, Juan C. Troncoso, Robert F. Dannals, Alena Savonenko, Catherine LaCourse, Martin G. Pomper, Catherine A. Foss, Andrew G. Horti, Hye Hyun Ahn
Publikováno v:
Proceedings of the National Academy of Sciences. 116:1686-1691
While neuroinflammation is an evolving concept and the cells involved and their functions are being defined, microglia are understood to be a key cellular mediator of brain injury and repair. The ability to measure microglial activity specifically an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb3038663818afc5d597dc779e294a4
https://doi.org/10.1073/pnas.1812155116
https://doi.org/10.1073/pnas.1812155116
Autor:
Hye Soo Lee, William D. Lewis, Sangeeta Ray Banerjee, Sridhar Nimmagadda, Yuchuan Wang, Xing Yang, Il Minn, Hye Hyun Ahn, Martin G. Pomper, Mary Brummet, Michael A. Gorin, Ronnie C. Mease, Soo Min Koo, Steven P. Rowe, Mohamad E. Allaf, Polina Sysa-Shah
Publikováno v:
Oncotarget
// Il Minn 1 , Soo Min Koo 1 , Hye Soo Lee 1 , Mary Brummet 1 , Steven P. Rowe 1 , Michael A. Gorin 2 , Polina Sysa-Shah 1 , William D. Lewis 1 , Hye-Hyun Ahn 1 , Yuchuan Wang 1 , Sangeeta Ray Banerjee 1 , Ronnie C. Mease 1 , Sridhar Nimmagadda 1 , M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd582bfb5495e5028750f7d72188ea71
https://doi.org/10.18632/oncotarget.10602
https://doi.org/10.18632/oncotarget.10602
Autor:
Biao Yu, Martin G. Pomper, Peng Xu, Emmanuel Datan, Qing-Li He, Hye Hyun Ahn, Jun O. Liu, Il Minn
Publikováno v:
iScience
iScience, Vol 23, Iss 9, Pp 101536-(2020)
iScience, Vol 23, Iss 9, Pp 101536-(2020)
Summary A major hurdle in the treatment of cancer is chemoresistance induced under hypoxia that is characteristic of tumor microenvironment. Triptolide, a potent inhibitor of eukaryotic transcription, possesses potent antitumor activity. However, its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1adeb7ae586054c560794445483163ba
https://pubmed.ncbi.nlm.nih.gov/33083765
https://pubmed.ncbi.nlm.nih.gov/33083765