Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Hye‐Young H. Kim"'
Autor:
John Kim, Ian Spears, Clara Erice, Hye-Young H. Kim, Ned A. Porter, Caitlin Tressler, Elizabeth W. Tucker
Publikováno v:
Neurobiology of Disease, Vol 202, Iss , Pp 106721- (2024)
Tuberculous (TB) meningitis is the deadliest form of extrapulmonary TB which disproportionately affects children and immunocompromised individuals. Studies in pulmonary TB have shown that Mycobacterium tuberculosis can alter host lipid metabolism to
Externí odkaz:
https://doaj.org/article/ddedd996dfea47ca90a8bdd08de80f30
Autor:
Syed Masood, Hye-Young H. Kim, Edward R. Pennington, Keri A. Tallman, Ned A. Porter, Philip A. Bromberg, Rebecca L. Rice, Avram Gold, Zhenfa Zhang, James M. Samet
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103199- (2024)
Intracellular redox homeostasis in the airway epithelium is closely regulated through adaptive signaling and metabolic pathways. However, inhalational exposure to xenobiotic stressors such as secondary organic aerosols (SOA) can alter intracellular r
Externí odkaz:
https://doaj.org/article/b3f537d33a53496b96828ebccd9ff6cf
Autor:
Lin Zhu, Julia An, Sivaprakasam Chinnarasu, Thao Luu, Yasminye D. Pettway, Kelly Fahey, Bridget Litts, Hye-Young H. Kim, Charles R. Flynn, MacRae F. Linton, John M. Stafford
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Mounting evidence has shown that CETP has important physiological roles in adapting to chronic nutrient excess, specifically, to protect against diet-induced insulin resistance. However, the underlying mechanisms for the protective roles of CETP in m
Externí odkaz:
https://doaj.org/article/d13b563333c6492787d6d4eb6f12ac44
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 10, Pp 1916-1926 (2018)
Regulating blood cholesterol (Chol) levels by pharmacotherapy has successfully improved cardiovascular health. There is growing interest in the role of Chol precursors in the treatment of diseases. One sterol precursor, desmosterol (Des), is a potent
Externí odkaz:
https://doaj.org/article/50f5006f9d0b45b980c7fb46a72c0fbf
Autor:
Keri A. Tallman, Hye-Young H. Kim, Zeljka Korade, Thiago C. Genaro-Mattos, Phillip A. Wages, Wei Liu, Ned A. Porter
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 182-190 (2017)
The formation of lipid electrophile-protein adducts is associated with many disorders that involve perturbations of cellular redox status. The identities of adducted proteins and the effects of adduction on protein function are mostly unknown and an
Externí odkaz:
https://doaj.org/article/9d341d16b651429fb5861430ed2a297a
Autor:
Katherine Windsor, Thiago C. Genaro-Mattos, Hye-Young H. Kim, Wei Liu, Keri A. Tallman, Sayuri Miyamoto, Zeljka Korade, Ned A. Porter
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 10, Pp 2842-2850 (2013)
Lipid modifications aid in regulating (and misregulating) protein function and localization. However, efficient methods to screen for a lipid's ability to modify proteins are not readily available. We present a strategy to identify protein-reactive l
Externí odkaz:
https://doaj.org/article/27594e664deb44d0b7efdcc43d241e6d
Autor:
Alexia N Perryman, Hye-Young H Kim, Alexis Payton, Julia E Rager, Erin E McNell, Meghan E Rebuli, Heather Wells, Martha Almond, Jamie Antinori, Neil E Alexis, Ned A Porter, Ilona Jaspers
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285721 (2023)
BackgroundOzone (O3) exposure causes respiratory effects including lung function decrements, increased lung permeability, and airway inflammation. Additionally, baseline metabolic state can predispose individuals to adverse health effects from O3. Fo
Externí odkaz:
https://doaj.org/article/937c884b7a9f4b45801f46e9b64b6441
Autor:
Charlotte A. Love, Hye-Young H. Kim, Keri A. Tallman, Phillip W. Clapp, Ned A. Porter, Ilona Jaspers
Publikováno v:
Chemical Research in Toxicology. 36:565-569
Autor:
Zeljka Korade, Keri A. Tallman, Hye-Young H. Kim, Marta Balog, Thiago C. Genaro-Mattos, Aryamav Pattnaik, Károly Mirnics, Asit K. Pattnaik, Ned A. Porter
Publikováno v:
ACS Pharmacology & Translational Science. 5:1086-1096
Cholesterol is ubiquitous in cells; it plays a critical role in membrane structure and transport as well as in intracellular trafficking processes. There are suggestions that cholesterol metabolism is linked to innate immunity with inhibitors of DHCR
Autor:
Renjie Jin, Connor Forbes, Nicole L. Miller, Douglas Strand, Thomas Case, Justin M. Cates, Hye‐Young H. Kim, Phillip Wages, Ned A. Porter, Krystin M. Mantione, Sarah Burke, James L. Mohler, Robert J. Matusik
Publikováno v:
The Prostate. 82:1378-1388
The development of benign prostatic hyperplasia (BPH) and medication-refractory lower urinary tract symptoms (LUTS) remain poorly understood. This study attempted to characterize the pathways associated with failure of medical therapy for BPH/LUTS.Tr