Výsledky vyhledávání - "Hyaluronic Acid Binding"

Akademický článek

Validation and evaluation of a common biomarker in human cancers sera protein detected by a monoclonal antibody UNIVmAb

Autor: D. Manjunath, Sunil B. Kumaraswamy, Shashidhar Aladhi Venkatakrishniah, Hitesh Nidumanda Appaiah, Anil Thomas, Shib D. Banerjee

Publikováno v: BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)

Abstract Objective Management and diagnosis of multiple human cancers remains a challenge and search for a common biomarker is still debatable. In this manuscript we have evaluated the use of monoclonal antibody UNIVmAb, to detect the protein (H11) a

Externí odkaz: https://doaj.org/article/90c1873cd60043a8b6c856b064896686

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Akademický článek

Additional Hyaluronic Acid Binding Selection Decreased Sperm DNA Damage after Conventional Semen Preparation in Infertile Patient with Abnormal Semen Analysis

Autor: Roungsin Choavaratana, M.D., Isarin Thanaboonyawat, M.D., MMedSci, Yaowapa Chongpensuklert, M.D., Japarath Prechapanich, M.D., Suphadtra Phornwilardsiri, M.C., Morou Stavroula Maria, MMedSci, Ketsara Sitthirit, B.Sc.

Publikováno v: Siriraj Medical Journal, Vol 70, Iss 3, Pp 213-218 (2018)

Objective: To study the benefit of combining conventional sperm preparation methods with hyaluronic acid binding in selecting spermatozoa with less DNA damage in infertile patients with abnormal semen analysis. Methods: Forty-six semen samples obta

Externí odkaz: https://doaj.org/article/db462b5e46304e07ac7c21d6a9e0f8cd

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Akademický článek

Sperm selection for assisted reproduction by prior hyaluronan binding: the HABSelect RCT

Autor: Jackson Kirkman-Brown, Sue Pavitt, Yacoub Khalaf, Sheena Lewis, Richard Hooper, Siladitya Bhattacharya, Arri Coomarasamy, Vinay Sharma, Daniel Brison, Gordon Forbes, Robert West, Allan Pacey, Kate Brian, Rachel Cutting, Virginia Bolton, David Miller

Publikováno v: Efficacy and Mechanism Evaluation, Vol 6, Iss 1 (2019)

Background: Sperm selection for intracytoplasmic sperm injection (ICSI) has traditionally relied on standardised methods of sperm processing combined with subjective sperm selection (motility/morphology). In 2012, live birth rates (LBRs) stood at ≈

Externí odkaz: https://doaj.org/article/a0252a05d2e74d969383baa49477a978

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Akademický článek

CD44: molecular interactions, signalling and functions in the nervous system.

Autor: Grzegorz Marek Wilczynski, Joanna eDzwonek

Publikováno v: Frontiers in Cellular Neuroscience, Vol 9 (2015)

CD44 is the major surface hyaluronan receptor implicated in intercellular and cell-matrix adhesion, cell migration and signalling. It is a transmembrane, highly glycosylated protein with several isoforms resulting from alternative gene splicing. The

Externí odkaz: https://doaj.org/article/0401d60fc37b41309854bd368b5d2085

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Glycocalyx mechanotransduction mechanisms are involved in renal cancer metastasis

Autor: Heriberto Moran, Limary M. Cancel, Peigen Huang, Sylvie Roberge, Tuoye Xu, John M. Tarbell, Lance L. Munn

Publikováno v: Matrix Biology Plus
Matrix Biology Plus, Vol 13, Iss, Pp 100100-(2022)

Highlights • Mechanotransduction through cell surface GAGs is a potential driver of metastasis. • SAHA, a histone deacetylase inhibitor, reduces tumor cell NDST1 and HS. • SAHA blocked metastasis of highly metastatic renal carcinoma cells in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6554547f15ec2891cde433f14b3369c9
https://pubmed.ncbi.nlm.nih.gov/35106474

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Male subfertility and oxidative stress

Autor: Claudia A Reyes-San-Martin, Romana Schirhagl, Jorien T.M. Scholten, Eus G. J. M. Arts, Aldona Mzyk, Astrid E. P. Cantineau, Thamir Hamoh, Emily P. P. Evans, Arturo E. Llumbet

Publikováno v: Redox Biology, 46:102071. Elsevier
Redox Biology
Redox Biology, Vol 46, Iss, Pp 102071-(2021)

To date 15% of couples are suffering from infertility with 45–50% of males being responsible. With an increase in paternal age as well as various environmental and lifestyle factors worsening these figures are expected to increase. As the so-called

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e491696450cf000852aa5d38849108a
https://research.rug.nl/en/publications/9edaf543-a764-4e8e-a835-48415d899cce

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Hyaluronic Acid-Binding, Anionic, Nanoparticles Inhibit ECM Degradation and Restore Compressive Stiffness in Aggrecan-Depleted Articular Cartilage Explants

Autor: Vanessa F. C. Dartora, Marcus Deloney, Alyssa Panitch, Parssa Garoosi, Blaine A. Christiansen

Publikováno v: Pharmaceutics, vol 13, iss 9
Pharmaceutics, Vol 13, Iss 1503, p 1503 (2021)
Pharmaceutics
Volume 13
Issue 9

Joint trauma results in the production of inflammatory cytokines that stimulate the secretion of catabolic enzymes, which degrade articular cartilage. Molecular fragments of the degraded articular cartilage further stimulate inflammatory cytokine pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea3e65a57b226d1a2551a2b571b8a0e
https://escholarship.org/uc/item/77w523x7

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