The Role of NF-κB Triggered Inflammation in Cerebral Ischemia

Autor: Teresa Jover-Mengual, Jee-Yeon Hwang, Hyae-Ran Byun, Brenda L. Court-Vazquez, José M. Centeno, María C. Burguete, R. Suzanne Zukin

Publikováno v: Frontiers in Cellular Neuroscience, Vol 15 (2021)

Cerebral ischemia is a devastating disease that affects many people worldwide every year. The neurodegenerative damage as a consequence of oxygen and energy deprivation, to date, has no known effective treatment. The ischemic insult is followed by an

Externí odkaz: https://doaj.org/article/80b6336ba2af40218f4a0fbf5b4096d9

Obesity and downregulated hypothalamic leptin receptors in male metallothionein-3-null mice

Autor: Hyae-Ran Byun, Dong-Kyu Kim, Jae-Young Koh

Publikováno v: Neurobiology of Disease, Vol 44, Iss 1, Pp 125-132 (2011)

In the present study, we examined whether metallothionein-3 (Mt3), a zinc-binding protein that is specifically enriched in a brain, plays a role in obesity and hypothalamic leptin signaling in mice. Upon aging, male Mt3-null mice gained more body wei

Externí odkaz: https://doaj.org/article/29f3f80ba27f49d8a626f3f859112d4a

Gadd45b Acts as Neuroprotective Effector in Global Ischemia-Induced Neuronal Death

Autor: Ah Rhang Cho, Fabrizio Pontarelli, Teresa Jover-Mengual, Christopher Dejesus, Hyae Ran Byun, Jee Yeon Hwang, R. Suzanne Zukin, Chang Hoon Cho

Publikováno v: International Neurourology Journal
International Neurourology Journal, Vol 23, Iss Suppl 1, Pp S11-21 (2019)
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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Purpose: Transient global ischemia arising in human due to cardiac arrest causes selective, delayed neuronal death in hippocampal CA1 and cognitive impairment. Growth arrest and DNA-damage-inducible protein 45 beta (Gadd45b) is a wellknown molecule i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb28f53daacd817b69a7952e817df1c
http://europepmc.org/articles/PMC6433207

Host Genetic Background and Gut Microbiota Contribute to Differential Metabolic Responses to Fructose Consumption in Mice

Autor: Ira Kurtz, In Sook Ahn, Xia Yang, Aldons J. Lusis, Elaine Y. Hsiao, Ingrid Cely, Peter Cohn, Jennifer M. Lang, Graciel Diamante, Christine A. Olson, Hyae Ran Byun, Zhe Ying, Guanglin Zhang, Fernando Gomez-Pinilla, Jessica Ding

Publikováno v: J Nutr
The Journal of nutrition, vol 150, iss 10

BackgroundIt is unclear how high fructose consumption induces disparate metabolic responses in genetically diverse mouse strains.ObjectiveWe aim to investigate whether the gut microbiota contributes to differential metabolic responses to fructose.Met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06b0a1972a1c3fe61103c78a1eb8545
https://pubmed.ncbi.nlm.nih.gov/32856048

Differential metabolic and multi-tissue transcriptomic responses to fructose consumption among genetically diverse mice

Autor: Yuqi Zhao, Fernando Gomez-Pinilla, Hyae Ran Byun, Le Shu, Jason Hong, Karthick Chella Krishnan, Xia Yang, Montgomery Blencowe, Zhe Ying, Guanglin Zhang

Publikováno v: Biochimica et biophysica acta. Molecular basis of disease, vol 1866, iss 1
Biochim Biophys Acta Mol Basis Dis

The escalating prevalence of metabolic syndrome (MetS) poses significant risks to type 2 diabetes mellitus, cardiovascular diseases, and non-alcoholic fatty liver disease. High fructose intake has emerged as an environmental risk for MetS and the ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ed450d432231aa85b684ed23a940ae
https://escholarship.org/uc/item/5927z56q