Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hyae Rim, Kang"'
Publikováno v:
Animal Cells and Systems, Vol 28, Iss 1, Pp 294-302 (2024)
The cytoplasmic FMR1-interacting protein 2 (CYFIP2) have diverse molecular functions in neurons, including the regulation of actin polymerization, mRNA translation, and mitochondrial morphology and function. Mutations in the CYFIP2 gene are associate
Externí odkaz:
https://doaj.org/article/f0ac53f13c2549b19204034ecff52b36
Publikováno v:
Animal Cells and Systems, Vol 27, Iss 1, Pp 94-102 (2023)
ABSTRACTCytoplasmic FMR1-interacting protein 2 (CYFIP2) is an evolutionarily conserved multifunctional protein that regulates the neuronal actin cytoskeleton, mRNA translation and transport, and mitochondrial morphology and function. Supporting its c
Externí odkaz:
https://doaj.org/article/56dac2550704490587243d59157ad780
Autor:
Muwon Kang, Yinhua Zhang, Hyae Rim Kang, Seoyeong Kim, Ruiying Ma, Seungjoon Lee, Yunho Yi, Chunmei Jin, Dongmin Lee, Eunjoon Kim, Kihoon Han
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S588- (2023)
Externí odkaz:
https://doaj.org/article/f11f3a7958ca4da193691b5d03372ec9
Autor:
Yoonhee Kim, Tae Hee Ko, Chunmei Jin, Yinhua Zhang, Hyae Rim Kang, Ruiying Ma, Huiling Li, Jong-Il Choi, Kihoon Han
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Shank3 is a member of the Shank family proteins (Shank1–3), which are abundantly present in the postsynaptic density (PSD) of neuronal excitatory synapses. As a core scaffold in the PSD, Shank3 plays a critical role in organizing the macromolecular
Externí odkaz:
https://doaj.org/article/4809dd1322b645638fa70cb197674b80
Autor:
Chunmei Jin, Yeunkum Lee, Hyojin Kang, Kwon Jeong, Joori Park, Yinhua Zhang, Hyae Rim Kang, Ruiying Ma, Hyunyoung Seong, Yoonhee Kim, Hosung Jung, Jin Young Kim, Yoon Ki Kim, Kihoon Han
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-5 (2021)
Abstract The SH3 and multiple ankyrin repeat domains 3 (Shank3) protein is a core organizer of the macromolecular complex in excitatory postsynapses, and its defects cause numerous synaptopathies, including autism spectrum disorders. Although the fun
Externí odkaz:
https://doaj.org/article/a5d01e752d3f48ab8b849fd86580ad31
Autor:
Gyu Hyun Kim, Yinhua Zhang, Hyae Rim Kang, Seung-Hyun Lee, Jiwon Shin, Chan Hee Lee, Hyojin Kang, Ruiying Ma, Chunmei Jin, Yoonhee Kim, Su Yeon Kim, Seok-Kyu Kwon, Se-Young Choi, Kea Joo Lee, Kihoon Han
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-5 (2020)
Abstract Variants of the cytoplasmic FMR1-interacting protein (CYFIP) gene family, CYFIP1 and CYFIP2, are associated with numerous neurodevelopmental and neuropsychiatric disorders. According to several studies, CYFIP1 regulates the development and f
Externí odkaz:
https://doaj.org/article/fde856e6f3674168aade04b64efb45ca
Publikováno v:
Animal Cells and Systems, Vol 23, Iss 6, Pp 380-383 (2019)
Recent molecular genetic studies have suggested that two members of the cytoplasmic FMR1-interacting protein (CYFIP) gene family, CYFIP1 and CYFIP2, are causally associated with several brain disorders. However, the clinical features of individuals w
Externí odkaz:
https://doaj.org/article/5187cf67f3e7479b8b0b2b5f32eda44a
Autor:
Chunmei Jin, Hyojin Kang, Taesun Yoo, Jae Ryun Ryu, Ye-Eun Yoo, Ruiying Ma, Yinhua Zhang, Hyae Rim Kang, Yoonhee Kim, Hyunyoung Seong, Geul Bang, Sangwoo Park, Seok-Kyu Kwon, Woong Sun, Hyunkyung Kim, Jin Young Kim, Eunjoon Kim, Kihoon Han
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2021)
Variants of the SH3 and multiple ankyrin repeat domains 3 (SHANK3), which encodes postsynaptic scaffolds, are associated with brain disorders. The targeted alleles in a few Shank3 knock-out (KO) lines contain a neomycin resistance (Neo) cassette, whi
Externí odkaz:
https://doaj.org/article/3b0f76fae5d0442a8ae3a8d14537d7bc
Autor:
Muwon Kang, Yinhua Zhang, Hyae Rim Kang, Seoyeong Kim, Ruiying Ma, Yunho Yi, Seungjoon Lee, Yoonhee Kim, Huiling Li, Chunmei Jin, Dongmin Lee, Eunjoon Kim, Kihoon Han
Publikováno v:
Annals of Neurology. 93:155-163
Here, we report the generation and comprehensive characterization of a knockin mouse model for the hotspot p.Arg87Cys variant of the cytoplasmic FMR1-interacting protein 2 (CYFIP2) gene, which was recently identified in individuals diagnosed with Wes
Autor:
Ruiying Ma, Kaifang Pang, Hyojin Kang, Yinhua Zhang, Geul Bang, Sangwoo Park, Eunha Hwang, Jae Ryun Ryu, Yujin Kwon, Hyae Rim Kang, Chunmei Jin, Yoonhee Kim, Su Yeon Kim, Seok‐Kyu Kwon, Doyoun Kim, Woong Sun, Jin Young Kim, Kihoon Han
Publikováno v:
Journal of Neurochemistry. 162:190-206