Pre-clinical evidence for the efficacy and safety of α-amylase inhibitory peptides from cumin (Cuminum cyminum) seed

Autor: Hwee-Leng Siow, Gee-Jun Tye, Chee-Yuen Gan

Publikováno v: Journal of Functional Foods, Vol 35, Iss , Pp 216-223 (2017)

Inhibitor of α-amylase offers an effective strategy to modulate hyperglycemia. Three novel cumin-seed peptides (CSPs) were proposed as potent inhibitors according to previous study. This study was performed to further assess the clinical relevance o

Externí odkaz: https://doaj.org/article/4a4a4ccdb14c443c8e2a09a0fc8f3653

Extraction, identification, and structure–activity relationship of antioxidative and α-amylase inhibitory peptides from cumin seeds (Cuminum cyminum)

Autor: Hwee-Leng Siow, Chee-Yuen Gan

Publikováno v: Journal of Functional Foods, Vol 22, Iss , Pp 1-12 (2016)

Cumin seed-derived peptides were extracted, fractionated, and identified in this study. The three novel peptides produced were named as CSP1 (FFRSKLLSDGAAAAKGALLPQYW), CSP2 (RCMAFLLSDGAAAAQQLLPQYW), and CSP3 (DPAQPNYPWTAVLVFRH). These peptides exhibi

Externí odkaz: https://doaj.org/article/72bffd02044144948b0ffcc574a8bd7f

Contributors

Autor: Sunita Adhikari (Nee Pramanik), Cristóbal Noé Aguilar-González, Dominic Agyei, Giasuddin Ahmed, Taiwo O. Akanbi, Jasarat Ali, Uday S. Annapure, K. Aparna, Naufal Arshad, Juan A. Ascacio-Valdés, Preeti Bajpai, Nagamani Balagurusamy, Rintu Banerjee, Ambreen Bano, Arely Prado Barragán, K.C. Beulah, Sameer S. Bhagyawant, Ram Naresh Bharagava, Sugandha Bhatia, S. Bonsegna, Daniel Boone, Cesar S. Cardona-Felix, Deniz Cekmecelioglu, Lye Yee Chew, Pankaj Chowdhary, M.O. Daramola, Mohan Das, Bhaskar Datta, S. De Domenico, Orlando de la Rosa, Mariana Delgado-García, Prospero Di Pierro, M.L. Dotaniya, C.K. Dotaniya, Ashutosh Dubey, Marilena Esposito, Adriana C. Flores-Gallegos, Abril Flores-Maltos, Chee-Yuen Gan, Marleny García Lozano, Ivanoe Garcia-Galindo, C. Valeria L. Giosafatto, Ricardo Gómez-García, Anamika Gupta, Anmol Gupta, Tomy J. Gutiérrez, José L. Hoyos-Concha, Anna Ilyina, Amin Ismail, Babu Joseph, Hee-Kyoung Kang, Sercan Karav, Jeesoo Kim, Seong-Bo Kim, Doman Kim, Mohammed Kuddus, Awanish Kumar, Sanjay Kumar, Vinod Kumar, Debajyoti Kundu, So-Hyung Kwak, Danielle B. Lopes, Miriam Paulina Luevanos Escareño, Diana Luque, Loredana Mariniello, Duniesky Martinez García, José L. Martínez Hernández, Gloria A. Martínez-Medina, Isabela M. Martins, F.A. Masoodi, Anju Meshram, Mariela R. Michel-Michel, Emad A. Abada, Nandkishor More, Vinod Morya, Diana B. Muñiz-Márquez, Pushpa S. Murthy, Farah Naqash, Erika Nava-Reyna, Ying-Yuan Ngoh, Thi Thanh Hanh Nguyen, A. Nwakaudu, Cynthia Vanessa Ochoa Bañuelos, Indrawati Oey, C.E. Ofoedu, B.K. Ojha, D.C. Okafor, José M. Pais Chanfrau, Sócrates Palácios-Ponce, Neelam Pathak, Yadira Peña García, Jimmy Nuñez Pérez, Enrique Pérez Cruz, Brian Picazo, P. Poltronieri, Raffaele Porta, Sergi Maicas Prieto, Luis Enrique Cobos Puc, Mohamed Fawzy Ramadan, Pramod W. Ramteke, Hita Rastogi, Sajad Ahmad Rather, K.L. Regar, Leonor M. Rivera Intriago, Raúl Rodríguez-Herrera, Rosa Maria Rodríguez-Jasso, null Roohi, Héctor A. Ruiz, Nazamid Saari, Mohammed Sabbah, Abdulhameed Sabu, Shweta Sachan, Sanjay Sahay, A. Santino, Changseop Seo, Leonardo Sepúlveda, Dinesh Chandra Sharma, Swati Sharma, Arpita Shrivastava, Neeraj Shrivastava, Jose Alberto Silva Gonzalez, Poonam Singh, Jagriti Singh, Mahendra Singh, Pradeep Kumar Singh, Rachana Singh, Aditi Singh, Gauri Singhal, Hwee-Leng Siow, H.P. Sneha, Janeth Margarita Ventura Sobrevilla, Nurul Afifah Hidayatul Saufi Sofian, Paula Speranza, Nidhi Srivastava, Neha Srivastava, Gareth Gordon Syngai, Arun Tapal, Purnima Kaul Tiku, Gaik Theng Toh, José Juan Mateo Tolosa, Luis E. Trujillo Toledo, Sibel Uzuner, Aniruddha M. Vaidya, Janeth Ventura, A.K. Verma, Sandra Villareal-Morales, Archana Vimal, Ashutosh Yadav, Ghazala Yunus, Mohd Rehan Zaheer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d54e9075e7e9e74d171be5a706dc822
https://doi.org/10.1016/b978-0-12-813280-7.09990-4

Functional protein from cumin seed (Cuminum cyminum): Optimization and characterization studies

Autor: Hwee-Leng Siow, Chee-Yuen Gan

Publikováno v: Food Hydrocolloids. 41:178-187

Cumin seed protein isolate (CSPI) was found to be a potential source of bioactive protein. Box-Behnken Design was used in order to optimize the protein extraction parameters: extraction time ( X 1 : 0.5–1.5 h), extraction temperature ( X 2 : 20–4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4887ae5141208d999000e93a42e203d6
https://doi.org/10.1016/j.foodhyd.2014.04.017

Development of a workflow for screening and identification of α-amylase inhibitory peptides from food source using an integrated Bioinformatics-phage display approach: Case study - Cumin seed

Autor: Chee-Yuen Gan, Theam Soon Lim, Hwee-Leng Siow

Publikováno v: Food chemistry. 214

The main objective of this study was to develop an efficient workflow to discover α-amylase inhibitory peptides from cumin seed. A total of 56 unknown peptides was initially found in the cumin seed protein hydrolysate. They were subjected to 2 diffe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d451601d21f216ef386891a90e7d01c
https://pubmed.ncbi.nlm.nih.gov/27507449