Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Hwee L. Ng"'
Autor:
Xing Zhang, Mason Lai, Winston Chang, Iris Yu, Ke Ding, Jan Mrazek, Hwee L. Ng, Otto O. Yang, Dmitri A. Maslov, Z. Hong Zhou
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Leishmania donovani is a protozoan parasite that can cause fatal infections in humans. Here the authors present a high resolution cryoEM structure of the L. donovani80S ribosome and compare it to its human counterpart to provide insight into the basi
Externí odkaz:
https://doaj.org/article/1154743d0e8144f0856a3f08e5888496
Autor:
Aleksandr M Gorin, Yushen Du, Franklin Y Liu, Tian-Hao Zhang, Hwee L Ng, Christian Hofmann, William G Cumberland, Ren Sun, Otto O Yang
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006541 (2017)
Certain Major Histocompatibility-I (MHC-I) types are associated with superior immune containment of HIV-1 infection by CD8+ cytotoxic T lymphocytes (CTLs), but the mechanisms mediating this containment are difficult to elucidate in vivo. Here we prov
Externí odkaz:
https://doaj.org/article/d0010ea8075a45f3a2e7cfcf3ab01e0d
Publikováno v:
Journal of virology, vol 95, iss 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54798f5fbc9ddcc95ba0c73b1879cb3b
https://escholarship.org/uc/item/1x46z2rq
https://escholarship.org/uc/item/1x46z2rq
Autor:
Joseph Y Kim, Arumugam Balamurugan, Kodi Azari, Christian Hofmann, Hwee L Ng, Elaine F Reed, Suzanne McDiarmid, Otto O Yang
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136235 (2015)
Immune prophylaxis and treatment of transplanted tissue rejection act indiscriminately, risking serious infections and malignancies. Although animal data suggest that cellular immune responses causing rejection may be rather narrow and predictable ba
Externí odkaz:
https://doaj.org/article/7b0e54efd400407d85277990b4eb04d1
Autor:
Joseph Y Kim, Arumugam Balamurugan, Kodi Azari, Christian Hofmann, Hwee L Ng, Elaine F Reed, Suzanne McDiarmid, Otto O Yang
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0146008 (2015)
Externí odkaz:
https://doaj.org/article/5bae48122dd4438983625bc75ce008d4
Autor:
Otto O Yang, F Javier Ibarrondo, Charles Price, Lance E Hultin, Julie Elliott, Patricia M Hultin, Roger Shih, Mary Ann Hausner, Hwee L Ng, Jennifer Hoffman, Beth D Jamieson, Peter A Anton
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88621 (2014)
Mucosal immunity is central to sexual transmission and overall pathogenesis of HIV-1 infection, but the ability of vaccines to induce immune responses in mucosal tissue compartments is poorly defined. Because macaque vaccine studies suggest that ingu
Externí odkaz:
https://doaj.org/article/aabb0ec4ee86403e84bd97d2a892933e
Autor:
Hwee L. Ng, Paul Krogstad, Lars Bode, Kerri Bertrand, Deisy Contreras, Christina D. Chambers, Grace M. Aldrovandi, Nicole H. Tobin
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
BackgroundSARS-CoV-2 infections of infants and toddlers are usually mild but can result in life-threatening disease. SARS-CoV-2 RNA been detected in the breast milk of lactating women, but the potential role of breastfeeding in transmission to infant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ade2be1f32f7c4bb6bd20b02478ec4
https://doi.org/10.1101/2021.04.05.21254897
https://doi.org/10.1101/2021.04.05.21254897
Autor:
Martha J Lewis, Patricia Frohnen, F Javier Ibarrondo, Diane Reed, Varun Iyer, Hwee L Ng, Julie Elliott, Otto O Yang, Peter Anton
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75620 (2013)
The gut is the largest lymphoid organ in the body and a site of active HIV-1 replication and immune surveillance. The gut is a reservoir of persistent infection in some individuals with fully suppressed plasma viremia on combination antiretroviral th
Externí odkaz:
https://doaj.org/article/ec8e584b732741e483100f2ef4d7caf2
Autor:
Hwee L. Ng, Justin De La Cruz, Joseph M Kim, Otto O. Yang, Arumugam Balamurugan, Eric S. Daar, Karen Lam
Publikováno v:
Viral immunology, vol 31, iss 7
Epitope escape from HIV-1-targeted CD8(+) cytotoxic T lymphocyte (CTL) responses occurs rapidly after acute infection and contributes to the eventual failure of effective immune control of HIV-1 infection. Because the early CTL response is key in det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d160f1b9dcf5306be7b18a82b7aad5
https://doi.org/10.1089/vim.2018.0040
https://doi.org/10.1089/vim.2018.0040
Publikováno v:
AIDS (London, England). 33(10)
OBJECTIVE: To assess whether weakly recognized epitope variants induce anergy in HIV-1-specific CD8(+) T lymphocyte (CTL) clones as a mechanism of dysfunction. DESIGN: HIV-1-specific CTL clones were exposed to suboptimally recognized epitope variants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931ebd4e4104a543064f6897376ae6da
https://pubmed.ncbi.nlm.nih.gov/31306165
https://pubmed.ncbi.nlm.nih.gov/31306165