Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Hwangseo, Park"'
Autor:
Srimai Vuppala, Ramesh Kumar Chitumalla, Seyong Choi, Taeho Kim, Hwangseo Park, Joonkyung Jang
Publikováno v:
ACS Omega, Vol 9, Iss 1, Pp 994-1000 (2023)
Externí odkaz:
https://doaj.org/article/a2e6f08f5b93475e8de1fc491e10af49
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1509 (2023)
The hERG potassium channel serves as an annexed target for drug discovery because the associated off-target inhibitory activity may cause serious cardiotoxicity. Quantitative structure–activity relationship (QSAR) models were developed to predict i
Externí odkaz:
https://doaj.org/article/aa96ba85aeb346c1846009cfd54f653b
Autor:
Kyeonghye Guk, Hyeran Kim, Miyeon Lee, Yoon-Aa Choi, Seul Gee Hwang, Gaon Han, Hye-Nan Kim, Hongki Kim, Hwangseo Park, Dongeun Yong, Taejoon Kang, Eun-Kyung Lim, Juyeon Jung
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Rapid detection of antiviral resistant strains is important for effective clinical treatment. Here the authors develop an antibody which specifically binds to multidrug-resistant influenza virus and demonstrated detection in a number of different sys
Externí odkaz:
https://doaj.org/article/6615c370bf5d436589ce04f046cddbbb
Publikováno v:
Journal of Chemical Information and Modeling. 62:4500-4511
Bruton's tyrosine kinase (BTK) is responsible for the pathogenesis of various autoimmune diseases and chronic lymphocytic leukemia. However, the discovery of efficient medicines has seen limited success due to the constitutively active mutants that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d383a60ef7bdfd9fc114d1b4119ca64b
https://doi.org/10.1021/acs.jcim.2c00623
https://doi.org/10.1021/acs.jcim.2c00623
Autor:
S. J. Richard Prabakar, Amol Bhairuba Ikhe, Woon Bae Park, Kee‐Choo Chung, Hwangseo Park, Ki‐Jeong Kim, Docheon Ahn, Joon Seop Kwak, Kee‐Sun Sohn, Myoungho Pyo
Publikováno v:
Advanced Science, Vol 6, Iss 24, Pp n/a-n/a (2019)
Abstract Herein, graphite is proposed as a reliable Ca2+‐intercalation anode in tetraglyme (G4). When charged (reduced), graphite accommodates solvated Ca2+‐ions (Ca‐G4) and delivers a reversible capacity of 62 mAh g−1 that signifies the form
Externí odkaz:
https://doaj.org/article/816acba6f4794d428b99d4a7bbdcd4a5
Autor:
Hye-Yeoung Yun, Min Wook Kim, Hye Seon Lee, Wantae Kim, Ji Hye Shin, Hyunmin Kim, Ho-Chul Shin, Hwangseo Park, Byung-Ha Oh, Won Kon Kim, Kwang-Hee Bae, Sang Chul Lee, Eun-Woo Lee, Bonsu Ku, Seung Jun Kim
Publikováno v:
PLoS Biology, Vol 17, Iss 7, p e3000367 (2019)
Human papillomaviruses (HPVs) are causative agents of various diseases associated with cellular hyperproliferation, including cervical cancer, one of the most prevalent tumors in women. E7 is one of the two HPV-encoded oncoproteins and directs recrui
Externí odkaz:
https://doaj.org/article/0b8e663fb8d843b2b159a4d8c171da3f
Autor:
Tae Jin Jeon, Seong-Gyu Lee, Suk Hyun Yoo, Myeongbin Kim, Dabin Song, Joonghyun Ryu, Hwangseo Park, Deok-Soo Kim, Jaekyung Hyun, Ho Min Kim, Seong Eon Ryu
Publikováno v:
Antioxidants & Redox Signaling. 36:1101-1118
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e500412ebe0f955be5b3e5f5fa6480d6
https://doi.org/10.1089/ars.2021.0114
https://doi.org/10.1089/ars.2021.0114
Publikováno v:
Pharmaceuticals, Vol 14, Iss 3, p 275 (2021)
Background: the proviral insertion site of Moloney murine leukemia (PIM) 1 kinase has served as a therapeutic target for various human cancers due to the enhancement of cell proliferation and the inhibition of apoptosis. Methods: to identify effectiv
Externí odkaz:
https://doaj.org/article/975de424a7bf487ab1e93aff974aed26
Autor:
Krisada Sakchaisri, Sun-Ok Kim, Joonsung Hwang, Nak Kyun Soung, Kyung Ho Lee, Tae Woong Choi, Yongjun Lee, Chan-Mi Park, Naraganahalli R Thimmegowda, Phil Young Lee, Bettaswamigowda Shwetha, Ganipisetti Srinivasrao, Thi Thu Huong Pham, Jae-Hyuk Jang, Hye-Won Yum, Young-Joon Surh, Kyung S Lee, Hwangseo Park, Seung Jun Kim, Yong Tae Kwon, Jong Seog Ahn, Bo Yeon Kim
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173311 (2017)
We have identified the small molecule STK899704 as a structurally novel tubulin inhibitor. STK899704 suppressed the proliferation of cancer cell lines from various origins with IC50 values ranging from 0.2 to 1.0 μM. STK899704 prevented the polymeri
Externí odkaz:
https://doaj.org/article/53c5ed3bb2c74f4b8592b3078263b538
Autor:
Won-Tae Kim, Saemina Shin, Hyo Jeong Hwang, Min Kyu Kim, Han-Sung Jung, Hwangseo Park, Chun Jeih Ryu
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167527 (2016)
Previously, we showed that B-cell receptor associated protein 31 (BAP31), an endoplasmic reticulum (ER) membrane chaperone, is also expressed on the cell surface by two monoclonal antibodies (MAbs) 297-D4 and 144-A8. Both MAbs recognize the same line
Externí odkaz:
https://doaj.org/article/ac7d3ccb0596444798dee33a649780e4