Zobrazeno 1 - 2
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pro vyhledávání: '"Hwangeun Choi"'
Autor:
Yuancheng Mao, Chang Yeob Han, Lihua Hao, Younho Lee, Jung Beom Son, Hwangeun Choi, Mi Rin Lee, Jae Do Yang, Suk Kyun Hong, Kyung‐Suk Suh, Hee Chul Yu, Nam Doo Kim, Eun Ju Bae, Byung‐Hyun Park
Publikováno v:
Hepatology (Baltimore, Md.)REFERENCES. 76(2)
p21-activated kinase 4 (PAK4), an oncogenic protein, has emerged as a promising target for anticancer drug development. Its role in oxidative stress conditions, however, remains elusive. We investigated the effects of PAK4 signaling on hepatic ischem
Autor:
Jong-Wook Park, Chul-Su Baek, Shinwu Jeong, Jinho Lee, Sei-Hee Lee, Hwangeun Choi, Kyoung-Hee Kim
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:2292-2295
A novel series of 3,5-diaminoindazoles were prepared and found to be CDK inhibitors. Potent inhibitors against CDK1 and CDK2 were obtained by introduction of 1λ6-isothiazolidine-1,1-dioxide at 5-position of indazole. Anti-proliferative activities of