Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Hwan Tae Park"'
Autor:
Byeol-A Yoon, Young Hee Kim, Soo Hyun Nam, Hye-Jin Lee, Seong-il Oh, Namhee Kim, Kyeong-Hee Kim, Young Rae Jo, Jong Kuk Kim, Byung-Ok Choi, Hwan Tae Park
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Autophagy is a self-degradation system for recycling to maintain homeostasis. p62/sequestosome-1 (p62) is an autophagy receptor that accumulates in neuroglia in neurodegenerative diseases. The objective of this study was to determine the ele
Externí odkaz:
https://doaj.org/article/60ab188d4287449ab1de0957e4b8a4d9
Autor:
Young Hee Kim, Young Hye Kim, Yoon Kyung Shin, Young Rae Jo, Da Kyeong Park, Min‐Young Song, Byeol‐A. Yoon, Soo Hyun Nam, Jong Hyun Kim, Byung‐Ok Choi, Ha Young Shin, Seung Woo Kim, Se Hoon Kim, Young Bin Hong, Jong Kuk Kim, Hwan Tae Park
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 7, Pp 1292-1301 (2019)
Abstract Objective Myelinated Schwann cells (SCs) in adult peripheral nerves dedifferentiate into immature cells in demyelinating neuropathies and Wallerian degeneration. This plastic SC change is actively involved in the myelin destruction and clear
Externí odkaz:
https://doaj.org/article/23616be5233c4928bc8403b413168468
Publikováno v:
Cancer Cell International, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Schwannoma arising from peripheral nervous sheaths is a benign tumor. Methods To evaluate cell cytotoxicity, (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) tetrazolium reduction and terminal deoxynucleotidyltransfe
Externí odkaz:
https://doaj.org/article/190574cbda4f4a1a80a6ea5771e3bba2
Autor:
Eun Jung Sohn, Hwan Tae Park
Publikováno v:
Cancer Cell International, Vol 17, Iss 1, Pp 1-7 (2017)
Abstract Recent studies suggested that natural compounds are important in finding targets for cancer treatments. Autophagy (“self-eating”) plays important roles in multiple diseases and acts as a tumor suppressor in cancer. Here, we examined the
Externí odkaz:
https://doaj.org/article/356dcebaa0f744189fb0c15bdfbeee6a
Autor:
Ji-Su Lee, Eun Hyuk Chang, Ok Jae Koo, Dong Hwan Jwa, Won Min Mo, Geon Kwak, Hyo Won Moon, Hwan Tae Park, Young Bin Hong, Byung-Ok Choi
Publikováno v:
Neurobiology of Disease, Vol 100, Iss , Pp 99-107 (2017)
Charcot-Marie-Tooth disease (CMT) is a genetic disorder that can be caused by aberrations in >80 genes. CMT has heterogeneous modes of inheritance, including autosomal dominant, autosomal recessive, X-linked dominant, and X-linked recessive. Over 95%
Externí odkaz:
https://doaj.org/article/046a240c8f184ec19b972d729e7d7f0b
Autor:
Jinsung Yang, Min Ju Kim, Woongchang Yoon, Eun Young Kim, Hyunjin Kim, Yoonjeong Lee, Boram Min, Kyung Shin Kang, Jin H Son, Hwan Tae Park, Jongkyeong Chung, Hyongjong Koh
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006975 (2017)
DJ-1 is one of the causative genes for early onset familiar Parkinson's disease (PD) and is also considered to influence the pathogenesis of sporadic PD. DJ-1 has various physiological functions which converge on controlling intracellular reactive ox
Externí odkaz:
https://doaj.org/article/e80011c473d74ce18d81a3f2f2302180
Autor:
Monica Ghidinelli, Yannick Poitelon, Yoon Kyoung Shin, Dominique Ameroso, Courtney Williamson, Cinzia Ferri, Marta Pellegatta, Kevin Espino, Amit Mogha, Kelly Monk, Paola Podini, Carla Taveggia, Klaus-Armin Nave, Lawrence Wrabetz, Hwan Tae Park, Maria Laura Feltri
Publikováno v:
PLoS Biology, Vol 15, Iss 6, p e2001408 (2017)
Myelin is required for proper nervous system function. Schwann cells in developing nerves depend on extrinsic signals from the axon and from the extracellular matrix to first sort and ensheathe a single axon and then myelinate it. Neuregulin 1 type I
Externí odkaz:
https://doaj.org/article/5e668d87ab0946caa24c5bbe9b621d4d
Autor:
Tae Woo Gu, Woo Yong Bae, Hwan Tae Park, Jae Hoon Lee, Min Young Kang, Sung Wook Jeong, Yoon Kyung Shin
Publikováno v:
Clinical and Experimental Otorhinolaryngology, Vol 7, Iss 1, Pp 1-6 (2014)
ObjectivesTo examine the expression profile of Fas-Fas ligand (FasL) during glutamate (Glu)-induced spiral ganglion cell (SGC) apoptosis.MethodsCultured SGCs were treated with 10-mM, 25-mM, and 50-mM concentrations of Glu and incubated for 24 or 48 h
Externí odkaz:
https://doaj.org/article/ee9cd926df3f4b5aab79471f471fe22e
Autor:
Young Bin Hong, Jaesoon Joo, Young Se Hyun, Geon Kwak, Yu-Ri Choi, Ha Kyung Yeo, Dong Hwan Jwa, Eun Ja Kim, Won Min Mo, Soo Hyun Nam, Sung Min Kim, Jeong Hyun Yoo, Heasoo Koo, Hwan Tae Park, Ki Wha Chung, Byung-Ok Choi
Publikováno v:
PLoS Genetics, Vol 12, Iss 2, p e1005829 (2016)
Charcot-Marie-Tooth disease (CMT) is a heterogeneous group of peripheral neuropathies with diverse genetic causes. In this study, we identified p.I43N mutation in PMP2 from a family exhibiting autosomal dominant demyelinating CMT neuropathy by whole
Externí odkaz:
https://doaj.org/article/7d3a1c012e2d4792841fc3db70e1d610
Autor:
So Young Jang, Yoon Kyung Shin, So Young Park, Joo Youn Park, Seo-Hee Rha, Jong Kuk Kim, Hye Jeong Lee, Hwan Tae Park
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116624 (2015)
Peripheral nerve myelination involves dynamic changes in Schwann cell morphology and membrane structure. Recent studies have demonstrated that autophagy regulates organelle biogenesis and plasma membrane dynamics. In the present study, we investigate
Externí odkaz:
https://doaj.org/article/4e72353b5ac148129ebe9f09f90ead1a