Capnocytophaga canimorsus: a human pathogen feeding at the surface of epithelial cells and phagocytes.

Autor: Manuela Mally, Hwain Shin, Cécile Paroz, Regine Landmann, Guy R Cornelis

Publikováno v: PLoS Pathogens, Vol 4, Iss 9, p e1000164 (2008)

Capnocytophaga canimorsus, a commensal bacterium of the canine oral flora, has been repeatedly isolated since 1976 from severe human infections transmitted by dog bites. Here, we show that C. canimorsus exhibits robust growth when it is in direct con

Externí odkaz: https://doaj.org/article/6fbd5db0559e419ca0bf28acea3ee6af

Evidence for a LOS and a capsular polysaccharide in Capnocytophaga canimorsus

Autor: Francesco Renzi, Melanie Dol, Guy R. Cornelis, Estelle Hess, Mohamed Chami, Chantal Fiechter, Irina Sadovskaya, Ursula Sauder, Frédéric Lauber, Hwain Shin, Manuela Mally, Simon Ittig

Publikováno v: Renzi, F, Ittig, S J, Sadovskaya, I, Hess, E, Lauber, F, Dol, M, Shin, H, Mally, M, Fiechter, C, Sauder, U, Chami, M & Cornelis, G 2016, ' Evidence for a LOS and a capsular polysaccharide in Capnocytophaga canimorsus ', Scientific Reports . https://doi.org/10.1038/srep38914
Scientific Reports

Capnocytophaga canimorsus is a dog’s and cat’s oral commensal which can cause fatal human infections upon bites or scratches. Infections mainly start with flu-like symptoms but can rapidly evolve in fatal septicaemia with a mortality as high as 4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584db7fc4c31391c3e97e7575b0b6d97
https://doi.org/10.1038/srep38914

Resistance of Capnocytophaga canimorsus to killing by human complement and polymorphonuclear leukocytes

Autor: Ulrich Zaehringer, Chantal Fiechter, Guy R. Cornelis, Cécile Paroz, Manuela Mally, Hwain Shin, Salome Meyer

Publikováno v: Infection and Immunity. 77(6):2262-2271

Capnocytophaga canimorsus is a bacterium of the canine oral flora known since 1976 to cause rare but severe septicemia and peripheral gangrene in patients that have been in contact with a dog. It was recently shown that these bacteria do not elicit a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7ffae0f00b17bcc8206d11d6fa2707
https://doi.org/10.1128/IAI.01324-08

Escape from Immune Surveillance byCapnocytophaga canimorsus

Autor: Guy R. Cornelis, Cécile Paroz, Hwain Shin, Manuela Mally, Marina Kuhn

Publikováno v: The Journal of Infectious Diseases. 195:375-386

Capnocytophaga canimorsus, a commensal bacterium from dogs' mouths, can cause septicemia or meningitis in humans through bites or scratches. Here, we describe and characterize the inflammatory response of human and mouse macrophages on C. canimorsus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630d3376a0384137a46de2b45b536a88
https://doi.org/10.1086/510243

The dependence receptor DCC (deleted in colorectal cancer) defines an alternative mechanism for caspase activation

Autor: Patrick Mehlen, Véronique Corset, Laure Granger, Dale E. Bredesen, Xin Ye, Hwain Shin, Christelle Forcet

Publikováno v: Proceedings of the National Academy of Sciences. 98:3416-3421

The expression of DCC (deleted in colorectal cancer) is often markedly reduced in colorectal and other cancers. However, the rarity of point mutations identified in DCC coding sequences and the lack of a tumor predisposition phenotype in DCC hemizygo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2669ad43b8b798698a24ca89b133fdaf
https://doi.org/10.1073/pnas.051378298