Zobrazeno 1 - 10
of 456
pro vyhledávání: '"Hwa T"'
Publikováno v:
Proc. Natl. Acad. Sci. 106(1), 67-72 (2009)
Understanding the molecular determinants of specificity in protein-protein interaction is an outstanding challenge of postgenome biology. The availability of large protein databases generated from sequences of hundreds of bacterial genomes enables va
Externí odkaz:
http://arxiv.org/abs/0901.1248
Publikováno v:
Proc Natl Acad Sci 104(14): pp. 6043-6048 (2007)
It is the goal of systems biology to understand the behavior of the whole in terms of the knowledge of the parts. This is hard to achieve in many cases due to the difficulty of characterizing the many constituents and their complex web of interaction
Externí odkaz:
http://arxiv.org/abs/q-bio/0703056
Autor:
Bundschuh, R., Hwa, T.
The formation of secondary structures by a random RNA sequence is studied as a model system for the sequence-structure problem omnipresent in biopolymers. Several toy energy models are introduced to allow detailed analytical and numerical studies. Fi
Externí odkaz:
http://arxiv.org/abs/cond-mat/0107210
Autor:
Bundschuh, R., Hwa, T.
Formation of RNA secondary structures is an example of the sequence-structure problem omnipresent in biopolymers. A theoretical question of recent interest is whether a random RNA sequence undergoes a finite temperature glass transition. We answer th
Externí odkaz:
http://arxiv.org/abs/cond-mat/0106029
We study the pinning of vortices in thin film superconductors by magnetic dots in the London approximation. A single dot is in general able to pin multiple field-induced vortices, up to a saturation number n_s, which can be much larger than one. Howe
Externí odkaz:
http://arxiv.org/abs/cond-mat/0003462
Autor:
Bundschuh, R., Hwa, T.
The statistical mechanics of heteropolymer structure formation is studied in the context of RNA secondary structures. A designed RNA sequence biased energetically towards a particular native structure (a hairpin) is used to study the transition betwe
Externí odkaz:
http://arxiv.org/abs/cond-mat/9903089
Publikováno v:
Phys. Rev. B 57, 8235 (1998)
The pinning of an inhomogeneous elastic medium by a disordered substrate is studied analytically and numerically. The static and dynamic properties of a $D$-dimensional system are shown to be equivalent to those of the well known problem of a $D$-dim
Externí odkaz:
http://arxiv.org/abs/cond-mat/9709224
We analyze the recently proposed "pattern-matching" phase of a Gaussian random heteropolymer adsorbed on a disordered substrate [S. Srebnik, A.K. Chakraborty and E.I. Shakhnovich, Phys. Rev. Lett. 77, 3157 (1996)]. By mapping the problem to that of a
Externí odkaz:
http://arxiv.org/abs/cond-mat/9707079
The effect of ambient disorders and sequence heterogeneities on the reptation of a long polymer is studied with the aid of a disordered tube model. The dynamics of a random heteropolymer is found to be much slower than that of a homopolymer due to co
Externí odkaz:
http://arxiv.org/abs/cond-mat/9706262
Autor:
Muñoz, M. A., Hwa, T.
Nonlinear diffusion is studied in the presence of multiplicative noise. The nonlinearity can be viewed as a ``wall'' limiting the motion of the diffusing field. A dynamic phase transition occurs when the system ``unbinds'' from the wall. Two differen
Externí odkaz:
http://arxiv.org/abs/cond-mat/9702217