Zobrazeno 1 - 10 of 130 pro vyhledávání: '"Hwa Jin Park"'
1
Akademický článek
Inhibitory effects of thromboxane A2 generation by ginsenoside Ro due to attenuation of cytosolic phospholipase A2 phosphorylation and arachidonic acid release
Autor: Jung-Hae Shin, Hyuk-Woo Kwon, Man Hee Rhee, Hwa-Jin Park
Publikováno v: Journal of Ginseng Research, Vol 43, Iss 2, Pp 236-241 (2019)
Background: Thromboxane A2 (TXA2) induces platelet aggregation and promotes thrombus formation. Although ginsenoside Ro (G-Ro) from Panax ginseng is known to exhibit a Ca2+-antagonistic antiplatelet effect, whether it inhibits Ca2+-dependent cytosoli
Externí odkaz: https://doaj.org/article/8f03096e4b184633a9ca7bf1ffe6f4ad
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2
Akademický článek
The inhibitory activity of ginsenoside Rp4 in adenosine diphosphate-induced platelet aggregation
Autor: Young-Min Son, Da-Hye Jeong, Hwa-Jin Park, Man-Hee Rhee
Publikováno v: Journal of Ginseng Research, Vol 41, Iss 1, Pp 96-102 (2017)
Background: Korean ginseng, Panax ginseng Meyer, has been used as a traditional oriental medicine to treat illness and promote health for several thousand years. Ginsenosides are the main constituents for the pharmacological effects of P. ginseng. Si
Externí odkaz: https://doaj.org/article/4d8b5365253145f59b175cccbda271de
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3
Akademický článek
Vasodilator-stimulated phosphoprotein-phosphorylation by ginsenoside Ro inhibits fibrinogen binding to αIIb/β3 in thrombin-induced human platelets
Autor: Jung-Hae Shin, Hyuk-Woo Kwon, Hyun-Jeong Cho, Man Hee Rhee, Hwa-Jin Park
Publikováno v: Journal of Ginseng Research, Vol 40, Iss 4, Pp 359-365 (2016)
Background: Glycoprotein IIb/IIIa (αIIb/β3) is involved in platelet adhesion, and triggers a series of intracellular signaling cascades, leading to platelet shape change, granule secretion, and clot retraction. In this study, we evaluated the effec
Externí odkaz: https://doaj.org/article/7138941b1f12492c89ea9876326f42de
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4
Akademický článek
Total saponin from Korean Red Ginseng inhibits binding of adhesive proteins to glycoprotein IIb/IIIa via phosphorylation of VASP (Ser157) and dephosphorylation of PI3K and Akt
Autor: Hyuk-Woo Kwon, Jung-Hae Shin, Hyun-Jeong Cho, Man Hee Rhee, Hwa-Jin Park
Publikováno v: Journal of Ginseng Research, Vol 40, Iss 1, Pp 76-85 (2016)
Background: Binding of adhesive proteins (i.e., fibrinogen, fibronectin, vitronectin) to platelet integrin glycoprotein IIb/IIIa (αIIb/β3) by various agonists (thrombin, collagen, adenosine diphosphate) involve in strength of thrombus. This study w
Externí odkaz: https://doaj.org/article/f0fe358e0a8342f2b46f59caa557cf64
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5
Akademický článek
Inhibitory effects of total saponin from Korean Red Ginseng on [Ca2+]i mobilization through phosphorylation of cyclic adenosine monophosphate-dependent protein kinase catalytic subunit and inositol 1,4,5-trisphosphate receptor type I in human platelets
Autor: Jung-Hae Shin, Hyuk-Woo Kwon, Hyun-Jeong Cho, Man Hee Rhee, Hwa-Jin Park
Publikováno v: Journal of Ginseng Research, Vol 39, Iss 4, Pp 354-364 (2015)
Background: Intracellular Ca2+([Ca2+]i) is a platelet aggregation-inducing molecule. Therefore, understanding the inhibitory mechanism of [Ca2+]i mobilization is very important to evaluate the antiplatelet effect of a substance. This study was carrie
Externí odkaz: https://doaj.org/article/23229b86901b4a8db3a1c48019a1c23c
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6
Akademický článek
The inhibitory mechanism of crude saponin fraction from Korean Red Ginseng in collagen-induced platelet aggregation
Autor: Bo Ra Jeon, Su Jung Kim, Seung Bok Hong, Hwa-Jin Park, Jae Youl Cho, Man Hee Rhee
Publikováno v: Journal of Ginseng Research, Vol 39, Iss 3, Pp 279-285 (2015)
Background: Korean Red Ginseng has been used as a traditional oriental medicine to treat illness and to promote health for several thousand years in Eastern Asia. It is widely accepted that ginseng saponins, ginsenosides, are the major active ingredi
Externí odkaz: https://doaj.org/article/a3219a9920984dcca194cd43e559ffdc
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8
The antithrombotic effect of caffeic acid is associated with a cAMP-dependent pathway and clot retraction in human platelets
Autor: Hwa-Jin Park, Gi Suk Nam, Kyung-Soo Nam
Publikováno v: Thrombosis Research. 195:87-94
Caffeic acid (CA) is a polyphenol widely distributed in the plant kingdom. Studies have shown CA possesses antithrombotic activity in mouse cerebral arterioles in vivo and inhibits platelet aggregation in vitro. However, little is known regarding the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf77427994c96bf86cbeaacad5502390
https://doi.org/10.1016/j.thromres.2020.07.024
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10
Inhibitory effects of thromboxane A2 generation by ginsenoside Ro due to attenuation of cytosolic phospholipase A2 phosphorylation and arachidonic acid release
Autor: Hyuk-Woo Kwon, Hwa-Jin Park, Man Hee Rhee, Jung-Hae Shin
Publikováno v: Journal of Ginseng Research, Vol 43, Iss 2, Pp 236-241 (2019)
Journal of Ginseng Research
Background: Thromboxane A2 (TXA2) induces platelet aggregation and promotes thrombus formation. Although ginsenoside Ro (G-Ro) from Panax ginseng is known to exhibit a Ca2+-antagonistic antiplatelet effect, whether it inhibits Ca2+-dependent cytosoli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5f1254a26dfc061f3349a92018998e
https://doi.org/10.1016/j.jgr.2017.12.007
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