Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Huyen Thi Lam Nguyen"'
Autor:
Peyton J. Tebon, Bowen Wang, Alexander L. Markowitz, Ardalan Davarifar, Brandon L. Tsai, Patrycja Krawczuk, Alfredo E. Gonzalez, Sara Sartini, Graeme F. Murray, Huyen Thi Lam Nguyen, Nasrin Tavanaie, Thang L. Nguyen, Paul C. Boutros, Michael A. Teitell, Alice Soragni
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract High throughput drug screening is an established approach to investigate tumor biology and identify therapeutic leads. Traditional platforms use two-dimensional cultures which do not accurately reflect the biology of human tumors. More clini
Externí odkaz:
https://doaj.org/article/cdb49d87278049f08e97471afd0ff5af
Autor:
Huyen Thi Lam Nguyen, Alice Soragni
Publikováno v:
STAR Protocols, Vol 1, Iss 2, Pp 100056- (2020)
Summary: Tumor organoids are promising tools for cancer biology investigations and pre-clinical drug screenings because they are often representative of the histology and drug responses of patients. Here, we introduce a facile protocol to overcome te
Externí odkaz:
https://doaj.org/article/f74a4ec4fc3842e4ac4f2f67ba01431c
Autor:
Huyen Thi Lam Nguyen, Emily Kohl, Jessica Bade, Stefan E. Eng, Anela Tosevska, Ahmad Al Shihabi, Jenny J. Hong, Sarah Dry, Paul C. Boutros, Andre Panossian, Sara Gosline, Alice Soragni
Localized cutaneous neurofibromas (cNFs) are benign tumors that arise in the dermis of patients affected by Neurofibromatosis Type 1 syndrome (NF1). cNFs are fundamentally benign lesions: they do not undergo malignant transformation or metastasize. N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae584b5bd8b4866c2a5987dc4824b182
https://doi.org/10.1101/2022.11.07.515469
https://doi.org/10.1101/2022.11.07.515469
Autor:
Maite Calucho, ZiMing Cheng, Huyen Thi-Lam Nguyen, Ahmad Al Shihabi, Hector Gonzalez-Cantu, Qianjin Guo, Maneesha Thaker, Nicole Bechmann, Graeme Eisenhofer, Yanli Ding, Patricia Dahia, Alice Soragni
Publikováno v:
Cancer Research. 83:195-195
Pheochromocytomas and paragangliomas (PPGL) are rare catecholamine-secreting neuroendocrine tumors known for their genetic diversity. They can be categorized in discrete molecular subgroups, including tumors presenting with pseudohypoxia or kinase si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6fb936d8c3a681bb6ddd0cda63d8cd2
https://doi.org/10.1158/1538-7445.am2023-195
https://doi.org/10.1158/1538-7445.am2023-195
Publikováno v:
Biomedical Research and Therapy. 7:3855-3859
Introduction: Anti-tumor drug screening is the most popular technique in drug discovery. In this technique, various agents were tested for their cytotoxicity on cell lines, particularly cancer cell lines. Since most of these agents are weakly soluble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c00098ce3ebd7a4fc4b06ee7b57a2e06
https://doi.org/10.15419/bmrat.v7i7.614
https://doi.org/10.15419/bmrat.v7i7.614
Autor:
Bowen Wang, Peyton J. Tebon, Alexander L. Markowitz, Graeme F. Murray, Huyen Thi Lam Nguyen, Nasrin Tavanaie, Thang L. Nguyen, Paul C. Boutros, Alice Soragni, Michael A. Teitell
Publikováno v:
Conference on Lasers and Electro-Optics.
We develop a method to apply a high-throughput quantitative phase imaging-based assay to functional biomass accumulation measurements of 3D tumor organoids with single-organoid resolution, and demonstrate its utility for drug screening and therapy se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e81719493e27d8579a78e020bc9a3fad
https://doi.org/10.1364/cleo_at.2022.atu5i.5
https://doi.org/10.1364/cleo_at.2022.atu5i.5
Autor:
Peyton J. Tebon, Bowen Wang, Alexander L. Markowitz, Ardalan Davarifar, Patrycja Krawczuk, Graeme Murray, Huyen Thi Lam Nguyen, Nasrin Tavanaie, Thang L. Nguyen, Paul C. Boutros, Michael A. Teitell, Alice Soragni
High-throughput drug screening is an established approach to investigate tumor biology and identify therapeutic leads. Traditional platforms for high-throughput screening use two-dimensional cultures of immortalized cell lines which do not accurately
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ff57eb5b117e3bcd315fb7c927b6dbc
https://doi.org/10.1101/2021.10.03.462896
https://doi.org/10.1101/2021.10.03.462896
Autor:
Nhan Lu-Chinh Phan, Ngu Van Trinh, Viet Quoc Pham, Huyen Thi-Lam Nguyen, Hanh Thi Le, Phong Minh Le, Ngoc Kim Phan, Sinh Truong Nguyen, Phuc Van Pham, Binh Thanh Vu, Toan Linh Nguyen
Publikováno v:
OncoTargets and therapy
Phuc Van Pham,1 Hanh Thi Le,1 Binh Thanh Vu,1 Viet Quoc Pham,1 Phong Minh Le,1 Nhan Lu-Chinh Phan,1 Ngu Van Trinh,1 Huyen Thi-Lam Nguyen,1 Sinh Truong Nguyen,1 Toan Linh Nguyen,2 Ngoc Kim Phan1 1Laboratory of Stem Cell Research and Application, Unive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2706ff88e4dc732bedb62dafef508adb
https://doi.org/10.2147/ott.s105239
https://doi.org/10.2147/ott.s105239
Autor:
Huyen Thi Lam Nguyen, Robert Damoiseaux, Nicholas M. Bernthal, Jane Yanagawa, Nasrin Tavanaie, Alice Soragni, Scott D. Nelson, Noah Federman, Ardy Davarifar, Francis J. Hornicek
Publikováno v:
Cancer Research. 80:3914-3914
Chordoma is a rare malignant tumor that arises from embryonic remnants of the notochord (Sahyouni et al, J Neurosurg Spine, 2018). This tumor is highly chemotherapy resistant, and there are no known compounds which have demonstrated clinically signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be8074aab6eade02e1ed394aa9ba4395
https://doi.org/10.1158/1538-7445.am2020-3914
https://doi.org/10.1158/1538-7445.am2020-3914
Publikováno v:
Biomedical Research and Therapy. 3
Three-dimensional (3D) cultures are becoming increasingly popular due to their ability to mimic tissue-like structures more effectively than monolayer cultures. In cancer research, the natural tumor characteristics and architecture are more closely m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fed94f9f53d1a402dcf287755a96ea1c
https://doi.org/10.7603/s40730-016-0022-8
https://doi.org/10.7603/s40730-016-0022-8