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Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 74:253-257
Serological surveillance for up to two years of 114 patients with laboratory confirmed scrub typhus showed that antibody to Rickettsia tsutsugamushi as demonstrated by the indirect fluorescent antibody test is short-lived. The mean reversion time fro
Publikováno v:
Japanese Journal of Medical Science and Biology. 33:231-234
Fifty-one Rickettsia tsutsugamushi isolates from small mammals collected in central Peninsular Malaysia serologically characterized by direct immunofluorescence using eight prototype strains. Karp-related (TA763, TA686, TA716) antigens were found in
Publikováno v:
Journal of Infectious Diseases. 140:811-814
Minimal clinical and hematologic signs were observed in silvered leaf monkeys inoculated intradermally with four strains of Rickettsia tsutsugamushi, both virulent and avirulent for laboratory mice. The clinical response of the monkeys to the infecti
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 25:900-905
A microimmunofluorescence (micro-IFA) test has been adapted to the study of naturally occurring antibody to Rickettsia tsutsugamushi in humans. The micro-IFA test was comparable to the present immlnofluorescent assay in sensitivity and reproducibilit
Publikováno v:
Japanese Journal of Medical Science and Biology. 35:255-259
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 27:121-124
Two communities of Orang Asli (aborigines) in Peninsular Malaysia were observed for evidence of Rickettsia tsutsugamushi infection over periods of 1–8 mo. Sequential sera were examined for antibody by the indirect immunofluorescence test. The incid
Publikováno v:
Japanese Journal of Medical Science and Biology. 32:337-344
One hundred and fourteen Rickettsia tsutsugamushi isolates, recovered from febrile patients in central Peninsular Malaysia, were antigenically analyzed by direct immunofluorescence using eight prototype strains. Twenty-nine antigenic types were detec
Publikováno v:
Japanese Journal of Medical Science and Biology. 32:179-184
The persistence of R. tsutsugamushi in tissues of experimentally infected mice for 565 days was demonstrated. Reactivation of apparently dormant infections was accomplished by inoculating the mice with a heterologous strain of the organism or treatme
Publikováno v:
Journal of Medical Entomology. 17:30-34
Dimethoate was utilized as a systemic acaricide for the control of trombiculid larvae (chiggers) in lalang and oil palm habitats in Peninsular Malaysia. Significant control was demonstrated within 3 months following application of a rodent bait consi