Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Huwate Yeerna"'
Autor:
Timothy V. Pham, Amélie Boichard, Aaron Goodman, Paul Riviere, Huwate Yeerna, Pablo Tamayo, Razelle Kurzrock
Publikováno v:
Molecular Oncology, Vol 14, Iss 8, Pp 1680-1694 (2020)
Hydrophobic neoantigens are more immunogenic because they are better presented by the major histocompatibility complex and better recognized by T cells. Tumor cells can evade the immune response by expressing checkpoints such as programmed death liga
Externí odkaz:
https://doaj.org/article/5273824955bb4e9c9ad1db9c769fbc15
Autor:
Jong Wook Kim, Christian Berrios, Miju Kim, Amy E Schade, Guillaume Adelmant, Huwate Yeerna, Emily Damato, Amanda Balboni Iniguez, Laurence Florens, Michael P Washburn, Kim Stegmaier, Nathanael S Gray, Pablo Tamayo, Ole Gjoerup, Jarrod A Marto, James DeCaprio, William C Hahn
Publikováno v:
eLife, Vol 9 (2020)
Alterations involving serine-threonine phosphatase PP2A subunits occur in a range of human cancers, and partial loss of PP2A function contributes to cell transformation. Displacement of regulatory B subunits by the SV40 Small T antigen (ST) or mutati
Externí odkaz:
https://doaj.org/article/32430c98748f4c4397dd12a2a347b246
Autor:
Daniel Martin, Maria S. Degese, Lynn Vitale-Cross, Ramiro Iglesias-Bartolome, Juan Luis Callejas Valera, Zhiyong Wang, Xiaodong Feng, Huwate Yeerna, Vachan Vadmal, Toshiro Moroishi, Rick F. Thorne, Moraima Zaida, Bradford Siegele, Sok C. Cheong, Alfredo A. Molinolo, Yardena Samuels, Pablo Tamayo, Kun Liang Guan, Scott M. Lippman, J. Guy Lyons, J. Silvio Gutkind
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Dysregulation of the Hippo signaling is a frequent event in human malignancies, but the molecular mechanisms remain unclear. Here the authors show that in head and neck squamous carcinoma, FAT1 interacts with the Hippo signaling complex, resulting in
Externí odkaz:
https://doaj.org/article/1b930320d9074414b8a21037b5706075
Autor:
Amélie Boichard, Timothy V. Pham, Huwate Yeerna, Aaron Goodman, Pablo Tamayo, Scott Lippman, Garrett M. Frampton, Igor F. Tsigelny, Razelle Kurzrock
Publikováno v:
OncoImmunology, Vol 8, Iss 3 (2019)
Tumor-associated neo-antigens are mutated peptides that allow the immune system to recognize the affected cell as foreign. Cells carrying excessive mutation load often develop mechanisms of tolerance. PD-L1/PD-1 checkpoint immunotherapy is a highly p
Externí odkaz:
https://doaj.org/article/62b164e42ceb4078844bcaa8c478e3da
Autor:
Natalie Galanina, Rafael Bejar, Michael Choi, Aaron Goodman, Matthew Wieduwilt, Carolyn Mulroney, Lisa Kim, Huwate Yeerna, Pablo Tamayo, Jo-Anne Vergilio, Tariq I. Mughal, Vincent Miller, Catriona Jamieson, Razelle Kurzrock
Publikováno v:
Cancers, Vol 11, Iss 1, p 11 (2018)
Background: The translation of genomic discoveries to the clinic is the cornerstone of precision medicine. However, incorporating next generation sequencing (NGS) of hematologic malignancies into clinical management remains limited. Methods: We descr
Externí odkaz:
https://doaj.org/article/59f97de4e6db45569ef4b1a06094bedc
Autor:
Jason K. Sicklick, Pablo Tamayo, Robert J. Wechsler-Reya, Jill P. Mesirov, Huwate Yeerna, Alexander T. Wenzel, Mayra Yebra, Chih-Min Tang, Stephanie Ting, Hyunho Yoon, Sudeep Banerjee
Supplementary FIG. 1 IM increases expression of stem markers and decreases KIT in human GIST. Supplementary FIG. 2 Cell cycle analysis of KITHigh and KITLow cells. Supplementary FIG. 3 TKI treatment enriches for KITlow GIST cells additional data. Sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afbdfc58ded654307036bfb5dc5daad
https://doi.org/10.1158/1535-7163.22521366.v1
https://doi.org/10.1158/1535-7163.22521366.v1
Autor:
Joseph A. Califano, J. Silvio Gutkind, Andrew B. Sharabi, Jacqueline Hubbard, William Kim, Huwate Yeerna, Pablo Tamayo, Theresa Guo, Yuki Saito, Mizuo Ando, Takahito Fukusumi, Sunny Haft, Yusuke Goto, Shuling Ren, Bharat A. Panuganti, Akihiro Sakai, Koji Ebisumoto, Sayed H. Sadat, Chao Liu
Expression of cannabinoids and their metabolites in plasma samples of HPV positive HNSCC patients identified by LC-MS/MS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ddb1ecd004fc1b29430aba19cfef376
https://doi.org/10.1158/1078-0432.22474940
https://doi.org/10.1158/1078-0432.22474940
Autor:
J. Silvio Gutkind, Scott M. Lippman, Qianming Chen, Pablo Tamayo, Anne N. Murphy, Panomwat Amornphimoltham, Zhiyong Wang, Xuefeng Zhang, Victoria H. Wu, Toshinori Ando, Yusuke Goto, Huwate Yeerna, Xingyu Wu
GSEA analysis of metformin-induced gene expression programs in NDI1 expressing tumor samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a8aac2a0ae1ba90fb000a2bccd89a9
https://doi.org/10.1158/0008-5472.22422414
https://doi.org/10.1158/0008-5472.22422414
Autor:
Joseph A. Califano, J. Silvio Gutkind, Andrew B. Sharabi, Jacqueline Hubbard, William Kim, Huwate Yeerna, Pablo Tamayo, Theresa Guo, Yuki Saito, Mizuo Ando, Takahito Fukusumi, Sunny Haft, Yusuke Goto, Shuling Ren, Bharat A. Panuganti, Akihiro Sakai, Koji Ebisumoto, Sayed H. Sadat, Chao Liu
Purpose:Human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) is associated with daily marijuana use and is also increasing in parallel with increased marijuana use in the United States. Our study is designed to define the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232ee0e05492e89c2b9ef60f7b64d20c
https://doi.org/10.1158/1078-0432.c.6528944
https://doi.org/10.1158/1078-0432.c.6528944
Autor:
J. Silvio Gutkind, Scott M. Lippman, Qianming Chen, Pablo Tamayo, Anne N. Murphy, Panomwat Amornphimoltham, Zhiyong Wang, Xuefeng Zhang, Victoria H. Wu, Toshinori Ando, Yusuke Goto, Huwate Yeerna, Xingyu Wu
supplementary methods and figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cab5579fd4281a657e00d31a82b6917
https://doi.org/10.1158/0008-5472.22422408
https://doi.org/10.1158/0008-5472.22422408