Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Huw E. L. Williams"'
Autor:
Cristina Padilla, Franck Quero, Marzena Pępczyńska, Paulo Díaz-Calderon, Juan Pablo Acevedo, Nicholas Byres, Jonny J. Blaker, William MacNaughtan, Huw E. L. Williams, Javier Enrione
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7489 (2023)
For biomedical applications, gelatin is usually modified with methacryloyl groups to obtain gelatin methacryloyl (GelMA), which can be crosslinked by a radical reaction induced by low wavelength light to form mechanically stable hydrogels. The potent
Externí odkaz:
https://doaj.org/article/b3ac3fc8362f4401ac247690b95e2223
Autor:
Samuel Furse, Adam J. Watkins, Nima Hojat, James Smith, Huw E. L. Williams, Davide Chiarugi, Albert Koulman
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Furse et al. use a purpose-built computational tool called Lipid Traffic Analysis to determine the spatial distribution of lipids throughout an organism. They use it to show that high paternal carbohydrate intake influences lipid metabolism in offspr
Externí odkaz:
https://doaj.org/article/69145bc415ce485fab5b9db61c31538e
Autor:
Samuel Furse, Laura C. Kusinski, Alison Ray, Coralie Glenn-Sansum, Huw E. L. Williams, Albert Koulman, Claire L. Meek
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11655 (2022)
Male fertility, as manifest by the quantity and progressive motility of spermatozoa, is negatively impacted by obesity, dyslipidaemia and metabolic disease. However, the relative distribution of lipids in spermatozoa and the two compartments which su
Externí odkaz:
https://doaj.org/article/6966b1430e514bf1955a33a1aaa77969
Autor:
Alaa T. Al-sandaqchi, Victoria Marsh, Huw E. L. Williams, Carl W. Stevenson, Hany M. Elsheikha
Publikováno v:
Microorganisms, Vol 8, Iss 9, p 1386 (2020)
Toxoplasma gondii (T. gondii), the causative agent of toxoplasmosis, is a frequent cause of brain infection. Despite its known ability to invade the brain, there is still a dire need to better understand the mechanisms by which this parasite interact
Externí odkaz:
https://doaj.org/article/f0f2992c9f6f4e968e9c36d58cecefe6
Autor:
Samuel Furse, Adam J. Watkins, Samuel Virtue, Antonio Vidal-Puig, Risha Amarsi, Huw E. L. Williams, Marika Charalambous, Albert Koulman
Publikováno v:
Analytical and Bioanalytical Chemistry
Detailed molecular analysis is of increasing importance in research into the regulation of biochemical pathways, organismal growth and disease. Lipidomics in particular is increasingly sought after as it provides insight into molecular species involv
Autor:
Rhys C. Griffiths, Huw E. L. Williams, Nick Mitchell, Jed Long, Frances R. Smith, Robert Layfield
Publikováno v:
Angewandte Chemie (International Ed. in English)
The development of site‐selective chemistry targeting the canonical amino acids enables the controlled installation of desired functionalities into native peptides and proteins. Such techniques facilitate the development of polypeptide conjugates t
Autor:
Alex Slater, Mark S. Searle, Lukasz Ciszewski, Linda Popplewell, Ngoc Lu-Nguyen, Andrew Brennan, Huw E. L. Williams, George Dickson
Publikováno v:
Nucleic Acids Research
Abnormal DUX4 expression in skeletal muscles plays a key role in facioscapulohumeral muscular dystrophy (FSHD) pathogenesis, although the molecular mechanisms regulating DUX4 expression are not fully defined. Using bioinformatic analysis of the genom
Autor:
Jed Long, Frances R. Smith, Nick Mitchell, Huw E. L. Williams, Daniel Scott, Rhys C. Griffiths, Robert Layfield, Neil J. Oldham
Publikováno v:
Angewandte Chemie. 134
Post-translational modifications (PTMs) enhance the repertoire of protein function and mediate or influence the activity of the majority of cellular processes. The preparation of site-specifically and homogeneously modified proteins to apply as tools
Autor:
Rhys C, Griffiths, Frances R, Smith, Jed E, Long, Daniel, Scott, Huw E L, Williams, Neil J, Oldham, Robert, Layfield, Nicholas J, Mitchell
Publikováno v:
Angewandte Chemie (International ed. in English). 61(2)
Post-translational modifications (PTMs) enhance the repertoire of protein function and mediate or influence the activity of many cellular processes. The preparation of site-specifically and homogeneously modified proteins, to apply as tools to unders
Autor:
Davide Chiarugi, Philip Stevenson, Nima Hojat, Huw E. L. Williams, Adam J. Watkins, Albert Koulman, Samuel Furse, James Smith
Publikováno v:
The FASEB Journal. 35