Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Huw D. Thomas"'
Autor:
Jill E. Hunter, Amy E. Campbell, Jacqueline A. Butterworth, Helene Sellier, Nicola L. Hannaway, Saimir Luli, Achilleas Floudas, Niall S. Kenneth, Adam J. Moore, Philip J. Brownridge, Huw D. Thomas, Jonathan Coxhead, Leigh Taylor, Peter Leary, Megan S.R. Hasoon, Andrew M. Knight, Michelle D. Garrett, Ian Collins, Claire E. Eyers, Neil D. Perkins
Publikováno v:
Biochemical Journal. 479:2087-2113
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420474f3df9a1bc6e42295d95643c992
https://doi.org/10.1042/bcj20220089
https://doi.org/10.1042/bcj20220089
Autor:
Kaye J. Williams, Nicola J. Curtin, Brian A. Telfer, Muhammed Babur, Ivanda Pavlovska, Suzanne Kyle, Huw D. Thomas, Marzieh Kamjoo, Majid Ali
PDF file - 81K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0da379a049b532b0f298f86559929b
https://doi.org/10.1158/1535-7163.22497237.v1
https://doi.org/10.1158/1535-7163.22497237.v1
Autor:
Kaye J. Williams, Nicola J. Curtin, Brian A. Telfer, Muhammed Babur, Ivanda Pavlovska, Suzanne Kyle, Huw D. Thomas, Marzieh Kamjoo, Majid Ali
PDF file - 41K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e89ff1ffdd978457433c8c241732127
https://doi.org/10.1158/1535-7163.22497234.v1
https://doi.org/10.1158/1535-7163.22497234.v1
Autor:
Helen L. Reeves, Nicola J. Curtin, Geoffrey I. Shapiro, Derek M. Manas, John Rose, David Newell, Alastair D. Burt, Jennifer Jackson, Huw D. Thomas, Despina Televantou, Catherine E. Willoughby, Laura Ogle, Augusto Villanueva, Clara Alsinet, Joanne M. Munck, Liam Cornell
Supplementary Figures 1-11. Supplementary Figure 1. DNA-PK expression and tumour specific PRKDC locus amplification Supplementary Figure 2. DDR gene expression in HCC cells Supplementary Figure 3: DDR protein expression and activity in HCC cells Supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7579644ee811838f9fe1ccae59f6d9
https://doi.org/10.1158/1078-0432.22458081.v1
https://doi.org/10.1158/1078-0432.22458081.v1
Autor:
Nicola J. Curtin, Stephen E. Webber, Lan-Zhen Wang, Donald Skalitzky, David R. Newell, Karen A. Maegley, Suzanne Kyle, Zdenek Hostomsky, Stacie Canan, Michael A. Batey, Christopher R. Calabrese, Huw D. Thomas
Adobe PDF - MCT-06-0552--Suppl_Table_S1.pdf from Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f0b3fff940d1a4cd79259b67d4afb5
https://doi.org/10.1158/1535-7163.22485801
https://doi.org/10.1158/1535-7163.22485801
Autor:
Nicola J. Curtin, Bernard T. Golding, Roger J. Griffin, David R. Newell, Marion Barton, Hannah Barlow, Julian S. Northen, Mei-Ju Lin, Lan-Zhen Wang, Kappusamy Saravanan, Huw D. Thomas
Antifolates have been used to treat cancer for the last 50 years and remain the mainstay of many therapeutic regimes. Nucleoside salvage, which depends on plasma membrane transport, can compromise the activity of antifolates. The cardiovascular drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77920703b9bfbb55eab67ef3d2666043
https://doi.org/10.1158/1535-7163.c.6532236
https://doi.org/10.1158/1535-7163.c.6532236
Autor:
Steven C. Clifford, Nicola J. Curtin, Deborah A. Tweddle, Alan V. Boddy, E. Ruth Plummer, Zdenek Hostomsky, Deborah J. Castelbuono, Yvette Drew, Evan A. Mulligan, Huw D. Thomas, Agata L. Rozanska, Rachel A. Daniel
Purpose: High-risk neuroblastoma is characterized by poor survival rates, and the development of improved therapeutic approaches is a priority. Temozolomide and topotecan show promising clinical activity against neuroblastoma. Poly(ADP-ribose) polyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689bae8a42187edf2016b2eb79d8a34f
https://doi.org/10.1158/1078-0432.c.6517512
https://doi.org/10.1158/1078-0432.c.6517512
Autor:
Steven C. Clifford, Nicola J. Curtin, Deborah A. Tweddle, Alan V. Boddy, E. Ruth Plummer, Zdenek Hostomsky, Deborah J. Castelbuono, Yvette Drew, Evan A. Mulligan, Huw D. Thomas, Agata L. Rozanska, Rachel A. Daniel
Supplementary Data from Inhibition of Poly(ADP-Ribose) Polymerase-1 Enhances Temozolomide and Topotecan Activity against Childhood Neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::591ee30bf0243646e9054a29e642993b
https://doi.org/10.1158/1078-0432.22440144
https://doi.org/10.1158/1078-0432.22440144
Autor:
Helen L. Reeves, Nicola J. Curtin, Geoffrey I. Shapiro, Derek M. Manas, John Rose, David Newell, Alastair D. Burt, Jennifer Jackson, Huw D. Thomas, Despina Televantou, Catherine E. Willoughby, Laura Ogle, Augusto Villanueva, Clara Alsinet, Joanne M. Munck, Liam Cornell
Data Supplement from DNA-PK—A Candidate Driver of Hepatocarcinogenesis and Tissue Biomarker That Predicts Response to Treatment and Survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8349f353f38afcfccaa5656e5483e61f
https://doi.org/10.1158/1078-0432.22458087
https://doi.org/10.1158/1078-0432.22458087
Autor:
Nicola J. Curtin, Bernard T. Golding, Roger J. Griffin, David R. Newell, Marion Barton, Hannah Barlow, Julian S. Northen, Mei-Ju Lin, Lan-Zhen Wang, Kappusamy Saravanan, Huw D. Thomas
Supplementary Fig. S3 from Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fca8588aa26a79a4189b98acd55ca00
https://doi.org/10.1158/1535-7163.22486086.v1
https://doi.org/10.1158/1535-7163.22486086.v1