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Ethical issues in implementation research: a discussion of the problems in achieving informed consent

Autor: Eccles Martin P, Hutton Jane L, Grimshaw Jeremy M

Publikováno v: Implementation Science, Vol 3, Iss 1, p 52 (2008)

Abstract Background Improved quality of care is a policy objective of health care systems around the world. Implementation research is the scientific study of methods to promote the systematic uptake of clinical research findings into routine clinica

Externí odkaz: https://doaj.org/article/1155bbbcaca24012ad52eaca00cbb5d8

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Akademický článek

Maximising response to postal questionnaires – A systematic review of randomised trials in health research

Autor: Gates Simon, Jørstad-Stein Ellen C, Hutton Jane L, Nakash Rachel A, Lamb Sarah E

Publikováno v: BMC Medical Research Methodology, Vol 6, Iss 1, p 5 (2006)

Abstract Background Postal self-completion questionnaires offer one of the least expensive modes of collecting patient based outcomes in health care research. The purpose of this review is to assess the efficacy of methods of increasing response to p

Externí odkaz: https://doaj.org/article/9f75aaa6a14148149c762b4b8c03749e

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Akademický článek

Peptides Derived from Vascular Endothelial Growth Factor B Show Potent Binding to Neuropilin-1.

Autor: Mota F; Wolfson Institute for Biomedical Research, University College London, Gower Street, London, WC1E 6BT, UK., Yelland T; The Institute of Structural and Molecular Biology, University College London, UK., Hutton JA; Wolfson Institute for Biomedical Research, University College London, Gower Street, London, WC1E 6BT, UK., Parker J; Centre for Cardiovascular Biology & Medicine, BHF Laboratories at University College London, UK., Patsiarika A; Wolfson Institute for Biomedical Research, University College London, Gower Street, London, WC1E 6BT, UK., Chan AWE; Wolfson Institute for Biomedical Research, University College London, Gower Street, London, WC1E 6BT, UK., O'Leary A; Centre for Cardiovascular Biology & Medicine, BHF Laboratories at University College London, UK., Fotinou C; The Institute of Structural and Molecular Biology, University College London, UK., Martin JF; Centre for Cardiovascular Biology & Medicine, BHF Laboratories at University College London, UK., Zachary IC; Centre for Cardiovascular Biology & Medicine, BHF Laboratories at University College London, UK., Djordjevic S; The Institute of Structural and Molecular Biology, University College London, UK., Frankel P; Institute of Cardiovascular Science, University College London, UK., Selwood DL; Wolfson Institute for Biomedical Research, University College London, Gower Street, London, WC1E 6BT, UK.

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2022 Jan 05; Vol. 23 (1), pp. e202100463. Date of Electronic Publication: 2021 Nov 03.

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Akademický článek

Novel Thienopyrimidine Inhibitors of Leishmania N -Myristoyltransferase with On-Target Activity in Intracellular Amastigotes.

Autor: Bell AS; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, U.K. W12 0BZ., Yu Z; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, U.K. W12 0BZ., Hutton JA; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, U.K. W12 0BZ., Wright MH; School of Chemistry, University of Leeds, Leeds, U.K. LS2 9JT., Brannigan JA; Structural Biology Laboratory, York Biomedical Research Institute, Department of Chemistry, University of York, York, U.K. YO10 5DD., Paape D; Centre for Immunology and Infection, York Biomedical Research Institute, Department of Biology, University of York, York, U.K. YO10 5NG., Roberts SM; Structural Biology Laboratory, York Biomedical Research Institute, Department of Chemistry, University of York, York, U.K. YO10 5DD., Sutherell CL; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, U.K. W12 0BZ., Ritzefeld M; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, U.K. W12 0BZ., Wilkinson AJ; Structural Biology Laboratory, York Biomedical Research Institute, Department of Chemistry, University of York, York, U.K. YO10 5DD., Smith DF; Centre for Immunology and Infection, York Biomedical Research Institute, Department of Biology, University of York, York, U.K. YO10 5NG., Leatherbarrow RJ; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, U.K. W12 0BZ., Tate EW; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, U.K. W12 0BZ.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2020 Jul 23; Vol. 63 (14), pp. 7740-7765. Date of Electronic Publication: 2020 Jul 14.

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Akademický článek

Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus.

Autor: Lim CSQ; Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, UK., Ha KP; MRC Centre for Molecular Bacteriology and Infection, Department of Medicine, Imperial College London, London SW7 2AZ, UK., Clarke RS; MRC Centre for Molecular Bacteriology and Infection, Department of Medicine, Imperial College London, London SW7 2AZ, UK., Gavin LA; Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, UK., Cook DT; Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, UK., Hutton JA; Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, UK., Sutherell CL; Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, UK., Edwards AM; MRC Centre for Molecular Bacteriology and Infection, Department of Medicine, Imperial College London, London SW7 2AZ, UK., Evans LE; Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, UK; MRC Centre for Molecular Bacteriology and Infection, Department of Medicine, Imperial College London, London SW7 2AZ, UK. Electronic address: l.evans@imperial.ac.uk., Tate EW; Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, UK. Electronic address: e.tate@imperial.ac.uk., Lanyon-Hogg T; Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, UK. Electronic address: t.lanyon-hogg@imperial.ac.uk.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2019 Oct 15; Vol. 27 (20), pp. 114962. Date of Electronic Publication: 2019 Jun 15.

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