E-DNA IM or ID delivery prime enhances antibody and T cell responses following recombinant gp120 env boost

Autor: Hutnick NA, Karuppiah M, Pollara J, Yan J, Myles DJ, Broderick K, Morrow M, Sardasai N, Montefiori D, Barnett S, Ferrari G, Weiner DB

Publikováno v: Retrovirology, Vol 9, Iss Suppl 2, p P364 (2012)

Externí odkaz: https://doaj.org/article/1799da99e5984e669ba8555d64080dc0

Chemokine-adjuvanted electroporated DNA vaccine induces substantial protection from simian immunodeficiency virus vaginal challenge.

Autor: Kutzler MA; Division of Infectious Diseases and HIV Medicine, The Department of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA., Wise MC; Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, U.S.A., Hutnick NA; Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, U.S.A., Moldoveanu Z; Department of Microbiology and Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA., Hunter M; Tulane National Primate Research Center and the Department of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University, Covington, Louisiana, USA., Reuter M; Department of Microbiology and Immunology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA., Yuan S; Department of Microbiology and Immunology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA., Yan J; Inovio Pharmaceuticals, Plymouth Meeting, Pennsylvania, USA., Ginsberg A; Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, U.S.A., Sylvester A; Inovio Pharmaceuticals, Plymouth Meeting, Pennsylvania, USA., Pahar B; Tulane National Primate Research Center and the Department of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University, Covington, Louisiana, USA., Carnathan D; Department of Microbiology and Immunology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA., Kathuria N; Division of Infectious Diseases and HIV Medicine, The Department of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA., Khan AS; Inovio Pharmaceuticals, Plymouth Meeting, Pennsylvania, USA., Montefiori D; Human Vaccine Institute, Duke University, Durham, North Carolina, USA., Sardesai NY; Inovio Pharmaceuticals, Plymouth Meeting, Pennsylvania, USA., Betts MR; Department of Microbiology and Immunology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA., Mestecky J; Department of Microbiology and Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA., Marx P; Tulane National Primate Research Center and the Department of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University, Covington, Louisiana, USA., Weiner DB; Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, U.S.A.

Publikováno v: Mucosal immunology [Mucosal Immunol] 2016 Jan; Vol. 9 (1), pp. 13-23. Date of Electronic Publication: 2015 May 06.

DNA vaccines targeting heavy chain C-terminal fragments of Clostridium botulinum neurotoxin serotypes A, B, and E induce potent humoral and cellular immunity and provide protection from lethal toxin challenge.

Autor: Scott VL; a Department of Pathology and Laboratory Medicine ; University of Pennsylvania ; Philadelphia , PA USA., Villarreal DO, Hutnick NA, Walters JN, Ragwan E, Bdeir K, Yan J, Sardesai NY, Finnefrock AC, Casimiro DR, Weiner DB

Publikováno v: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2015; Vol. 11 (8), pp. 1961-71.

Inducing humoral and cellular responses to multiple sporozoite and liver-stage malaria antigens using exogenous plasmid DNA.

Autor: Ferraro B; University of Pennsylvania School of Medicine, Department of Pathology and Laboratory Medicine, Philadelphia, Pennsylvania, USA., Talbott KT, Balakrishnan A, Cisper N, Morrow MP, Hutnick NA, Myles DJ, Shedlock DJ, Obeng-Adjei N, Yan J, Kayatani AK, Richie N, Cabrera W, Shiver R, Khan AS, Brown AS, Yang M, Wille-Reece U, Birkett AJ, Sardesai NY, Weiner DB

Publikováno v: Infection and immunity [Infect Immun] 2013 Oct; Vol. 81 (10), pp. 3709-20. Date of Electronic Publication: 2013 Jul 29.

Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.

Autor: Sonnenberg GF; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Monticelli LA, Alenghat T, Fung TC, Hutnick NA, Kunisawa J, Shibata N, Grunberg S, Sinha R, Zahm AM, Tardif MR, Sathaliyawala T, Kubota M, Farber DL, Collman RG, Shaked A, Fouser LA, Weiner DB, Tessier PA, Friedman JR, Kiyono H, Bushman FD, Chang KM, Artis D

Publikováno v: Science (New York, N.Y.) [Science] 2012 Jun 08; Vol. 336 (6086), pp. 1321-5. Date of Electronic Publication: 2012 Jun 06.