8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode

Autor: Paoletti, Julie, Assairi, Liliane, Gelin, Muriel, Huteau, Valérie, Nahori, Marie-Anne, Dussurget, Olivier, Labesse, Gilles, Pochet, Sylvie

Publikováno v: In European Journal of Medicinal Chemistry 29 November 2016 124:1041-1056

Structure-based design of NAD+ analogues targeting bacterial NAD kinases, promising targets for new antibiotics

Autor: Rahimova, Rahila, Nogaret, Pauline, Huteau, Valérie, Leseigneur, Clarisse, Gelin, Muriel, Clément, David, Dussurget, Olivier, Labesse, Gilles, Pochet, Sylvie, Blanc-Potard, Anne-Béatrice, Lionne, Corinne

Publikováno v: The Biochemistry Global Summit, 25th IUBMB Congress, 46th FEBS Congress, 15th PABMB Congress
The Biochemistry Global Summit, 25th IUBMB Congress, 46th FEBS Congress, 15th PABMB Congress, Portuguese Biochemical Society (SPB); IUBMB; FEBS; PABMB, Jul 2022, Lisbon, Portugal. pp.24, ⟨10.1002/2211-5463.13442⟩

International audience; Multi-drug resistance is a major public health problem that requires the urgent development of new antibiotics and therefore the identification of novel bacterial targets. The activity of nicotinamide adenine dinucleotide kina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2100::2299c7dfc656916d9278f64982c90e0b
https://hal.science/hal-03854164

A new synthetic access to furo[3,2- f]chromene analogues of an antimycobacterial

Autor: Alvey, Luke, Prado, Soizic, Huteau, Valérie, Saint-Joanis, Brigitte, Michel, Sylvie, Koch, Michel, Cole, Stewart T., Tillequin, François, Janin, Yves L.

Publikováno v: In Bioorganic & Medicinal Chemistry 2008 16(17):8264-8272

New Chemical Probe Targeting Bacterial NAD Kinase

Autor: Clément, David, Leseigneur, Clarisse, Gelin, Muriel, Coelho, Dylan, Huteau, Valérie, Lionne, Corinne, Labesse, Gilles, Dussurget, Olivier, Pochet, Sylvie

Publikováno v: Molecules
Molecules, 2020, 25 (21), pp.4893. ⟨10.3390/molecules25214893⟩
Molecules, MDPI, 2020, 25 (21), pp.4893. ⟨10.3390/molecules25214893⟩

International audience; Nicotinamide adenine dinucleotide (NAD) kinases are essential and ubiquitous enzymes involved in the tight regulation of NAD/nicotinamide adenine dinucleotide phosphate (NADP) levels in many metabolic pathways. Consequently, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::92108c11464aff1e783cef3d5acf248d
https://hal.science/hal-03030945

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